University of Nottingham

Aphasia treatment research: a decision-making tool to guide the design of phased trials from the Collaboration of Aphasia Trialists (CATs) trials for aphasia panel

Background Systematic reviews of randomised controlled trials with meta-analyses indicate that speech and language therapy for aphasia after stroke is effective in improving communication. However, high-quality evidence to identify an intervention’s target population (who), regim...

Psychological interventions to improve maternal mental health and resilience during pregnancy in the COVID-19 pandemic: a systematic review

BACKGROUND: During the COVID-19 pandemic, pregnant women experienced increased psychological distress, while access to routine mental health care was often disrupted. Psychological interventions may provide an effective strategy to support maternal mental health under these circu...

Management of high-risk (B3) breast lesions in symptomatic practice: evidence review and practical recommendations for multidisciplinary care

Borderline breast lesions (B3 lesions, also termed lesions of uncertain malignant potential or high-risk lesions) represent a heterogeneous group of entities associated with variable risks of malignancy. While the management of screen-detected B3 lesions has become increasingly s...

Prospects of green iron- and steelmaking via the FFC Cambridge process

The FFC Cambridge Process promises green iron-/steelmaking, where the respective metal oxides are used as the cathode in a molten electrolyte. Laboratory tests have validated the process at 500–900°C in molten chlorides, carbonates, fluorides or hydroxides. The reduction proceeds...

Swallowing therapy for dysphagia in acute and subacute stroke

RATIONALE: Post-stroke dysphagia ((PSD) impaired swallowing following stroke), increases risk of death, yet the effects of potential treatments are unclear. This review updates the 2018 review. OBJECTIVES: To assess the effects of swallowing therapies on swallowing impairment (SI...

Benefits and challenges of a Patient & Public Involvement (PPI) peer researcher

Involving a patient and public involvement (PPI) peer researcher with lived experience in clinical research is a relatively new concept and to our knowledge, has not been described in adult cardiac surgery. The integration of a PPI peer researcher with a lived experience of a sur...

Midproject Peer Assessment Effect on Group Dynamics and Transferable Skills

Abstract Peer assessment has been widely used in educational settings, particularly in group projects. Despite its known benefits, there is limited evidence on how the design of peer assessment activities influences group dynamics or how it can be used as a mechanism to foster th...

Physicochemical quality and emission characteristics of artisanal‑refined diesel in the Niger Delta region of Nigeria and their air quality implications

This study provides a novel integrated assessment linking the physicochemical properties of artisanal-refined diesel in the Niger Delta region to its combustion emission behaviour. Diesel samples from 30 refining sites in Bayelsa and Rivers States were analysed using ASTM methods...

Extracellular polymeric substances as key enablers for microalgal treatment and valorisation of malting and brewery wastewater

Malting and brewery wastewaters present environmental and economic challenges to the brewing industry due to their high organic loads and variable nutrient content, with chemical oxygen demand (COD) values ranging from 328 to 4500 mg/L and 910 to 8926 mg/L, respectively. Conventi...

Scalable Synthesisof a Masked Thiophenol as an Air-Stable,Odorless Intermediate to the Aurora Kinase Inhibitor Tozasertib (VX-680)

Abstract The use of thiophenols on process scales is fraught with challenges relating to their toxicity, malodor, and air sensitivity. We previously demonstrated that the Ni-catalyzed C–S coupling of aryl iodides and thiourea provides a discovery-scale route to S-aryl isothiouron...

Stability of Medicinal Nanoemulsions to Spaceflight: Insights From the StarMed Experiment

Space missions require liquid drug formulations that remain physically stable and exhibit predictable release under launch, microgravity, and handling stresses. This study examined melatonin‑loaded nanoemulsions flown on the MAPHEUS‑15 sounding rocket, comparing an uncoated nanoe...

The barrier is purely financial: analysis of the acceptance rate and peer review practice of predatory journals using AI generated papers

Unsolicited emails from predatory journals offer a quick opportunity to produce a first author publication for a fee. With increasing emphasis on first author publications for applications, interviews and jobs, the opportunity associated with such journals may encourage some to p...

Accelerated carbonation of recycled concrete aggregates: Binding of CO2 and decalcification of calcium-silicate-hydrate

Recycled concrete aggregates (RCA) are a valuable resource for reuse as aggregates in concrete and asphalt. However, the porous mortar adhering to the original aggregates and microcracks both in the mortar and at the interfaces result in increased water absorption and reduced mec...

Artificial Intelligence in Public Procurement: Aligning Operational Capacity, Legitimacy, and Public Value

ABSTRACT Public procurement is adopting artificial intelligence (AI) more slowly than private‐sector procurement, despite similar operational opportunities. We analyze this gap through Moore's Strategic Triangle (ST), focusing on public value, operational capacity, and legitimacy...

Promoting smoking cessation and preventing relapse to tobacco use following a smokefree mental health in‐patient stay: A multi‐centre randomised controlled feasibility study

Abstract Aims This study assessed the feasibility and acceptability of a new theory‐ and evidence‐based intervention designed to prevent return to pre‐admission smoking behaviours after discharge from a smokefree mental health in‐patient setting in the United Kingdom (UK). Design...

The Impact of Video Game Experience on Surgical Performance: A Systematic Review

OBJECTIVE: To assess whether video gaming experience is associated with improved surgical performance in the surgeon population across laparoscopic, robotic, and other surgical modalities, and evaluate its implications on surgical training and education. METHODS: A structured lit...

Stable isotopes as integrators of soil biogeochemistry and tree growth across contrasting hardwood forest soils

Abstract Background & aims Forest productivity and resilience are influenced by soil conditions; however, the mechanisms linking soil properties, isotopic signatures, and tree growth remain incompletely understood. This study evaluated whether soil carbon (δ 13 C) and nitroge...

Non-medical surgical delay increases one-year mortality following hip fracture

Aims: This study aimed to assess the association between surgical delay due to non-medical reasons and one-year mortality in patients with hip fracture, and to explore whether a dose-response relationship exists between increasing time to surgery and mortality risk. Methods: A re...