University of Nottingham

The ‘legging up’ burden: Hidden struggles of model minorities in racialized mentoring at work

Drawing on contemporaneous microstoria narrated by Black model minorities (BMMs), this paper theorizes the legging up burden: the implicit expectation that BMMs, positioned as token representatives of their race, will provide mentoring and support to organizational members with w...

Strategic roadmap for delivery of clinical trials in rare childhood central nervous system (CNS) tumours: a multi-stakeholder consensus

Abstract Rare paediatric central nervous system (CNS) tumours comprise a biologically-heterogeneous group of low-incidence diseases that present significant challenges to both therapeutic development and clinical research, limiting the availability of high-quality evidence to gui...

P1.201. Textbook Outcome After Oesophago-Gastric Cancer Surgery: Temporal Change Over 24 Years and Association With Survival

Abstract Topic Esophageal Cancer: Surgical Treatment of Esophageal Cancer – early outcomes and complications Background Outcomes after oesophago-gastric cancer surgery have improved over the last two decades, but it is unclear whether this reflects fewer complications, improved s...

Patient and public involvement and engagement in co-designing guidance for mental health professionals supporting neurodivergent children and young people in child and adolescent mental health services

Abstract Background Neurodivergent children and young people, including those with autism, attention-deficit/hyperactivity disorder and intellectual disability, experience higher rates of mental health difficulties than their neurotypical peers. Despite this increased need, many...

P1.200. Reducing Failure to Rescue Improves Long Term Survival After Oesophago-Gastric Cancer Surgery

Abstract Topic Esophageal Cancer: Surgical Treatment of Esophageal Cancer – early outcomes and complications Background Outcomes after oesophago-gastric cancer surgery have improved over time, and this is likely to be multifactorial. In addition to better oncologic treatments, sa...

Urinary Extracellular Vesicles as a Source of Biomarkers for Kidney Allograft Rejection: A Systematic Review

BACKGROUND: Kidney transplant rejection remains a leading cause of graft loss, and diagnosis still depends largely on invasive biopsies. Urinary extracellular vesicles (uEVs) offer a potential noninvasive alternative for detecting allograft rejection through molecular profiling o...

Languages and Concepts of European Civil Wars, 1917–39: An Introduction

Abstract This introduction opens a special issue on ‘Languages and Concepts of European Civil Wars, 1917–39’. Drawing on case studies of Russia, Finland, Ireland, Austria and Spain, the issue examines civil war as a struggle over language and political identity. Its articles cons...

Both CD8+ and CD4+ T regulatory cells are associated with poor survival in colorectal cancer

Abstract Previous studies in colorectal cancer have linked high levels of FoxP3 + regulatory T-cells (Treg) (CRC) to favourable prognosis. However, this contradicts the well-established immunosuppressive function of Treg. We resolved this conundrum using multiplex immunohistochem...

Practitioner psychologists’ experiences of delivering a cognitive behavioural therapy informed crisis intervention for psychosis in inpatient settings: a mixed methods investigation within the CRISIS study

Abstract Objectives Cognitive behaviour therapy for psychosis (CBTp) should be delivered in psychiatric inpatient settings, yet little is known about therapists’ perspectives on delivering it. This study examined therapists’ perspectives on delivering a crisis-focused CBTp-inform...

Maximizing stem body size may reduce the risk of postoperative periprosthetic fractures

Aims: There is concern around an increased risk of postoperative periprosthetic fracture (POPPF) with cemented polished taper slip (PTS) femoral components. We hypothesized that femoral constructs resulting in increased load on the cement mantle would be associated with higher PO...

Globalization and Market Power

ABSTRACT We use a large episode of trade liberalization in Spain to test a rich set of channels linking trade and markups. The effect of reductions in import tariffs on firm‐level and aggregate markups is pro‐competitive, but there are offsetting effects via other channels. We sh...

Air quality assessment in the context of landfill mining activities

Landfill mining (LFM) is a strategy aimed at mitigating any remaining potential adverse environmental impact of landfill sites whilst also recovering untapped commodities and energy for utilisation, as well as freeing up land resources for beneficial use. Many studies have highli...

Building a Physics-Aware AI Ecosystem for Solid-State Hydrogen Storage Materials

Abstract Hydrogen storage remains a central bottleneck for scalable hydrogen energy systems due to the multiscale and coupled nature of the thermodynamics, kinetics, and microstructural evolution of hydrogen storage materials (HSMs). Although artificial intelligence (AI) has acce...

EmotionaL and Language Recovery in Aphasia (ELLA): Codesigning and Proof-of-Concept Testing a Novel Intervention

Purpose: People with aphasia are at risk of becoming depressed, anxious, and isolated. They want therapy to focus on improving communication, confidence, and finding ways to live well; family members want to be involved in the therapy process. We aimed to codesign and test a nove...

Quantifying the Equine Pain Response to Paracetamol Administration in Horses With Chronic Lameness Already Receiving Non‐Steroidal Anti‐Inflammatories

ABSTRACT Paracetamol is used in horses alongside non‐steroidal anti‐inflammatories (NSAIDs) for multi‐modal analgesia; however to date there are few studies published which have investigated its analgesic effect in the horse. Horses were recruited to this study from a population...

Insulin resistance is associated with mammary mitochondrial dysfunction at the onset of human lactation

Insulin resistance (IR) has emerged as a risk factor for lactation insufficiency and delays the onset of milk secretion after childbirth, termed secretory activation (SA). This may cause inadequate infant weight gain and early breastfeeding cessation. However, the mechanisms unde...

Order amidst chaos: recognising patterns in the geography of out of area housing

One aspect of the UK housing crisis is the high number of households living in temporary accommodation. This paper looks at temporary accommodation households placed ‘out of area’ into other local authority areas. Whilst this may appear to be a chaotic picture of households being...

Assessing iron, zinc and calcium bioaccessibility using the INFOGEST method: Challenges and opportunities

Abstract Iron, zinc and calcium are essential minerals required for key physiological functions, including oxygen transport, immune function, enzymatic activity and bone health. Despite their importance, deficiencies remain widespread globally, driven in part by the poor bioavail...

In children requiring emergency vascular access, are intraosseous lines associated with significant long-term complications?

Intraosseous (IO) access is a technique increasingly used within trauma and emergency settings where immediate vascular access is required. It provides an effective alternative to intravenous access, particularly in paediatric patients where intravenous access is difficult, or wh...

Comparing experience intensity of AR and VR for contrasting phobia stimuli

Abstract Exposure-based therapy is a common psychological intervention for phobias and anxiety disorders, and exposure-based therapy using virtual reality (VR) and augmented reality (AR) have been evaluated as practical extensions of this method, producing similar experiences thr...