University of Naples Federico II

Proposal of partial safety factors for structural assessment of existing Italian highway bridges based on experimental data

Abstract Developed within the Consiglio Superiore dei Lavori Pubblici (Italian High Council of Public Works)–Rete dei Laboratori Universitari di Ingegneria Sismica e Strutturale (Network of University Laboratories of Earthquake and Structural Engineering) research program support...

Schizophrenia research in 2026: report from the annual meeting of the Schizophrenia International Research Society

Abstract SIRS 2026, held under the theme “Schizophrenia Research in the Era of Artificial Intelligence,” brought together researchers, clinicians, and persons with lived experience to take stock of a field whose tools for measuring, predicting, and intervening in psychosis have e...

A game-theoretic assessment of urban road-network vulnerability: a case study of Naples, Italy

Urban road-network vulnerability is difficult to assess when disruption probabilities are unknown and alternative paths perform differently under adverse network conditions. This study proposes a game-theoretic framework in which network users and an adversarial entity interact t...

A Kaizen perspective for managing human-technology continuous improvement in the digital age

Purpose The paper examines how digital technologies are transforming continuous improvement (CI) by altering the cognitive and relational dynamics that have long underpinned Kaizen-oriented learning. Design/methodology/approach This paper adopts a conceptual approach, drawing on...

The Broad Clinical Heterogeneity of TRNT1-Related Autoinflammatory Syndrome: A Comprehensive Review

Mutations in the tRNA Nucleotidyl Transferase 1 (TRNT1) gene have been associated with a systemic autoinflammatory disease (SAID) that presents with a wide clinical spectrum, ranging from severe and fatal forms to milder disorders. We conducted a literature review to provide a co...

Rotating Weyssenhoff fluids in linearized Einstein-Cartan theory

The Weyssenhoff fluid expands the ordinary perfect-fluid description of general relativity by taking into account the intrinsic spin of its constituent particles. Within the linearized regime of Einstein-Cartan theory, we investigate the exterior geometry produced by isolated slo...

Comparison of Biometric Measurements Between Anterior Segment Hyperparallel and Swept-Source Optical Coherence Tomography

Purpose: To evaluate the inter-device agreement between hyperparallel optical coherence tomography (HP-OCT) and swept-source OCT (SS-OCT) in quantitative anterior segment parameters. Methods: Phakic subjects aged ≥40 years were consecutively recruited at a tertiary eye hospital....

Hardware-in-the-loop validation of an MPC architecture for real-time equilibrium control of tokamak plasmas at RFX-mod2

This work deals with the real-time implementation of an equilibrium control system based on Model Predictive Control (MPC) for tokamak plasma operation at RFX-mod2. Such an architecture has been shown to address the challenging asymmetric constraints imposed by the one-quadrant p...

Changes in Mineral Profile of Portulaca oleracea L. Under Foliar Treatment with Sodium Selenate

The mineral composition of edible plants often changes as a result of selenium biofortification, which affects plant species tolerance and adaptability to Se supply, as well as nutritional value. To reveal the peculiarities of macro- and microelements in root–leaf–seed distributi...

Effect of seawater on the reactivity, microstructure, and strength of Roman-inspired lime-pozzolan binders

Roman marine concretes were frequently produced using seawater, yet the influence of seawater on lime-pozzolan reactions remains poorly quantified. In this work, pastes and mortars prepared with slaked lime and a natural pozzolan from the Phlegraean Fields were mixed with either...

Emerging therapeutic strategies and clinical trials in severe asthma management: current evidence and future directions

Introduction Biologic therapies have transformed the management of severe asthma, particularly in type 2-high disease, but important unmet needs remain. Incomplete responses, uncertainty in treatment positioning, and the lack of effective options for non-type 2 or mixed inflammat...

ACTN3 Variants Beyond Performance: Metabolic and Inflammatory Implications

Background: Athletic performance is a result of interaction between genetic and environmental factors, including training, nutrition, rest, hormonal and psychophysiological status. Numerous genes and polymorphisms can influence key physiological processes, such as muscle contract...

Training the Next Generation of Future Surgical Residents: A Scoping Review and Proposal for an Undergraduate Curriculum From the Italian Polispecialistic Society of Young Surgeons

AIM: The transition from medical school to surgical residency is marked by a persistent gap between theoretical instruction and clinical readiness. In Italy, variability in training programs across centers creates persistent gaps in residents’ medical education. Scientific societ...

Revisiting Inherited Metabolic Diseases ( IMDs ) Through the Lens of Selective Autophagy

ABSTRACT Selective autophagy is increasingly recognized as a fundamental quality‐control mechanism that complements bulk autophagy by enabling the targeted degradation of specific intracellular cargos, including mitochondria, endoplasmic reticulum (ER), lipid droplets, glycogen,...

Challenges and strategies for dredged sediment decision management in Venice lagoon (Italy)

This study presents the results of extensive sediment characterization campaigns conducted in 2024-2025 on more than 400 sediment cores collected across the Venice Lagoon, yielding approximately 1400 samples analyzed for chemical contamination and ecotoxicity. Investigated sedime...

Exogrammetry: A novel concept for extraoral relocation of scanning references in digital implant dentistry

Background: Complete-arch implant-position acquisition remains sensitive to large edentulous spans, interrupted reference surfaces, soft-tissue interference, and restricted posterior access. Various scanbody, auxiliary geometric, and photogrammetric approaches address these diffi...

Histatin-Based Metallopeptides Target Secondary Biofilms Derived from Candida albicans Persister Cells in Recurrent Vulvovaginal Candidiasis

Biofilm-associated persister cells contribute to the recurrence and treatment failure of Candida albicans infections. Here, two Histatin 5-derived peptides (P1 and P2) and their silver(I)-coordinated derivatives (M1 and M2) were evaluated against a vaginal C. albicans clinical is...

Risk factors for seroma formation following abdominoplasty: a systematic review and meta-analysis

Abstract Background Seroma is the most common complication following abdominoplasty. However, the risk factors associated with its development remain unclear, with inconsistent findings across studies. Objective To systematically evaluate and quantitatively synthesize risk factor...

Impact of GLP-1 Receptor Agonists on Cognitive Performance in Adults at Risk of Alzheimer’s Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Background/Objectives: Type 2 diabetes, a widely recognized risk factor of Alzheimer’s disease (AD), is mainly due to the role played by insulin resistance on neuronal degeneration. Mild Cognitive Impairment (MCI) also significantly increases the risk of developing AD by approxim...

Impact of surgical antibiotic prophylaxis on postoperative complications following dental extractions in dogs with severe periodontal disease: a retrospective observational study

Abstract Background Periodontal disease is the most prevalent oral disease affecting dogs and cats and often requiring surgical treatment. The use of perioperative surgical antimicrobial (SAP) prophylaxis in dental surgery remains a subject of ongoing debate. Dental extractions a...