University of Münster

From innovation to integration: what German mental health professionals think about peer-led youth discovery colleges

Abstract Mental health challenges among children and adolescents are increasing in Germany, highlighting the need for innovative, recovery-oriented approaches that complement existing mental health services. Discovery Colleges (DCs), a youth adaptation of the Recovery College mod...

On the Moufang condition for polar spaces

Abstract We provide direct constructions of nontrivial root elations of thick generalized quadrangles embedded in thick polar spaces of higher finite rank and show that all of these can be expressed as self-projectivities of length 4. This reveals a connection between the little...

Ferritin Complex Vaccine against Influenza A Using Screened Immunogenic Sequences from Fv-Antibody Library

Abstract A ferritin-based influenza A vaccine was developed. The immunogenic sequences of the nucleoprotein (NP) were screened using an autodisplayed Fv-antibody library, and the paratopes with a high-affinity binding affinity were analyzed through docking simulations. The result...

The Perfectionistic Self-Presentation Scale—Short Form (PSPS-SF): Development and Validation

This study aimed to develop and evaluate the psychometric properties of a brief version of the Perfectionistic Self-Presentation Scale (PSPS), a measure of the interpersonal expression of perfectionism. Adult participants (N = 2223; Mage = 36.67) from three samples completed all...

Multi-Methodological Characterization of Sleep Deprivation: From Standard EEG Power Spectra to Aperiodic Dynamics in Humans and Mice.

Sleep deprivation is a potent, rapid-acting therapeutic intervention for major depressive disorder, yet its underlying neural mechanisms remain poorly understood, hindering the development of predictive biomarkers. Here, we systematically characterize the electro-physiological si...

Tearing Down Scientific Boundaries: Frontiers in Medicinal Chemistry 2026

The Frontiers in Medicinal Chemistry (FiMC) was held in Münster from March 24 th to 27 th as the largest international Medicinal Chemistry conference in Germany. Welcoming more than 240 participants from around 20 countries, it was a vibrant conference, celebrating the community...

Nonlinear Responses of Anaerobic Methane Oxidation to Water Table Drawdown in Peatlands

Abstract Anaerobic oxidation of methane (AOM) serves as a key methane (CH4) sink that attenuates methane emissions from peatlands. Climate change has induced widespread water table drawdown in peatlands, but the response of AOM to the water table depth (WTD) and the temperature s...

Computer-Assisted Proofs for Geometry Optimization: From Crystallization to Carbon Nanotubes

Abstract. We present a framework based on computer-assisted proofs that turns geometry optimization simulations for atomistic structures into mathematical proofs. Starting from a numerically computed approximation of a local minimizer or saddle point, we use validated numerical c...

Exploring the Possibility of Extrinsic Anion Vacancies in Li6PS5Cl

Abstract The search for superionic conductors requires a deep understanding of the underlying crystal structure and local dynamic processes. Therefore, cationic and anionic substitutions are typically performed to monitor the resulting changes in the structure and ionic transport...

Pre-ejaculate – an overlooked body fluid with high amounts of DNA

Pre-ejaculate is a clear, sperm-free liquid secreted by the male bulbourethral glands. Since it is currently not a subject of routine forensic testing, pre-ejaculate is often overlooked. The aim of this study was to characterize the forensic value of pre-ejaculate: Pre-ejaculate...

Adenylation Domain Engineering Enables Biosynthesis of an Improved Polymyxin Antibiotic

ABSTRACT Polymyxins are potent nonribosomal peptide antibiotics, yet their clinical use is limited by a narrow therapeutic window and nephro‐/neurotoxicity. Conventional efforts to improve these agents rely on the incorporation of nonnatural building blocks that cannot be accesse...

Widefield optical coherence tomography angiography of fellow eyes in patients with Coats Disease

PURPOSE: Recent advances in retinal imaging have revealed vasculostructural alterations in fellow eyes of patients with Coats disease, thereby challenging the traditional concept of Coats disease as a strictly unilateral disorder. To further explore the phenotype of this retinal...

Social comparison threat and coping: affective, cognitive and behavioral outcomes in response to false performance-related feedback

Abstract Background Social comparisons shape our behavior. The general comparative processing model (gComp) suggests that evaluating one’s attributes against salient upward social standards elicits motivational appraisal ranging from threat to challenge, each typically associated...

A preliminary antimicrobial investigation of lactobacillus bulgaricus probiotic supernatants as an intracanal medication against mature E. faecalis biofilm in an ex-vivo dentin blocks model

AIM: To provide a preliminary assessment of the antimicrobial potential of Lactobacillus bulgaricus probiotic against mature Enterococcus faecalis biofilm in dentin model under ex-vivo conditions using confocal laser scanning microscopy (CLSM). METHODS: Lactobacillus bulgaricus a...

The Proteinase Activated Receptor-2 mediates Protective Immunity in Early Experimental Leishmaniasis

Resistance to Leishmania (L.) major depends on the development of a L. major-specific Th1 response, while Th2 differentiation results in susceptibility. We previously showed that the early microenvironment of infected skin delivers important signals for T cell differentiation. We...

Philophrosyne beckeri gen. et sp. nov., a microfossil with possible affinities to oomycetes from the Lower Devonian Rhynie cherts

Abstract The Lower Devonian Rhynie cherts contain a wide variety of microfossils with possible affinities to fungi or fungus-like organisms, only a fraction of which have been described and critically evaluated. Philophrosyne beckeri gen. et sp. nov. occurs in accumulations of de...

Robust circular cluster-based statistics for respiration-brain coupling

The rapidly developing research field of brain-body neuroscience faces methodological challenges, as analysts continue to develop new analysis strategies for robust statistics in the absence of established best practices. This quest for robust statistics is further complicated by...

When are digital services taxes optimal? Output taxes and profit shifting

Abstract Motivated by the introduction of digital services taxes (DSTs) in several European countries and the widespread use of revenue-based taxes where profit taxation is imperfect, this paper studies whether targeted output or commodity taxes can serve as surrogate profit taxe...

Exploring baryon semileptonic decays through polarization and entanglement

Abstract The unitarity of the Cabibbo–Kobayashi–Maskawa (CKM) matrix is a cornerstone of the standard model (SM). Precise tests of this unitarity require independent determinations of its elements, such as | V us |, which governs the transition between strange and up quarks. Curr...

Chronic exposure to aflatoxin B1, ochratoxin A, and citrinin in women and children and associated health risk characterization: blood biomonitoring evidence from rural Bangladesh

Abstract Dietary exposure to mycotoxins—including aflatoxins (AFs), ochratoxin A (OTA), and citrinin (CIT)—represents an important health risk, particularly in low-resource settings with widespread food contamination. This study investigates mycotoxin exposure among 712 participa...