University of Münster

Multiscale characterization of cortical signatures in positive and negative schizotypy:a worldwide ENIGMA study

Positive and negative schizotypy reflect distinct patterns of subclinical traits in the general population associated with neurodevelopmental and schizophrenia-spectrum pathologies. Yet, a comprehensive characterization of the unique and shared neuroanatomical signatures of these...

Prospects of HIV elimination among men who have sex with men: A systematic review of modeling studies

Abstract Background Despite advances in HIV treatment and prevention, men who have sex with men (MSM) remain disproportionately affected by HIV worldwide. This systematic review summarizes the results of mathematical modeling studies that evaluated whether interventions might eli...

Complementary Indicators of Knowledge Purporting and Their Validity

Overclaiming (OC)—the tendency to claim knowledge one does not possess—is predominantly assessed through self-report Overclaiming Questionnaires (OCQs). However, exclusive reliance on OCQs raises concerns about mono-method bias, limiting our understanding of knowledge purporting...

On the Reciprocal Structure of Adolescent Substance use and Delinquency - Results of a German Longitudinal Study

Abstract In recent years, studies have demonstrated a close relationship between substance use and delinquency among young people. However, the dynamics and directional structure of this relationship have long remained unclear. Studies in the United States suggest bidirectional e...

Variation in meningioma recurrence risk estimates across observational cohorts: the influence of calendar time, WHO classifications, geographical settings, and healthcare systems

Abstract Purpose Recurrence risk estimates underpin meningioma research, including molecular classification and clinical trial benchmarking, yet are often based on retrospective or historical data. The aim of this study was to assess the variation of recurrence risk estimates acr...

Pre-stimulus pupil-linked arousal enhances initial stimulus availability and accelerates decay in iconic memory

Abstract Pupil diameter reflects not only reflexive responses to light but also spontaneous fluctuations in arousal. Such pre-stimulus fluctuations may shape visual performance, yet it remains unclear whether they only affect perceptual sensitivity or decision processes in near-t...

Opening the black box of democracy in international business: polity, politics, and policy distances

In the current context of democratic backsliding, different political systems, such as democracies and autocracies, as well as political differences between democracies, play an important role in shaping economic relationships. Yet, studies of political factors in international b...

The SiO 2 abundance on the surfaces of the Moon and Mercury

The SiO2 abundance on rocky planetary surfaces is a key indicator for planetary crust composition and magmatic evolution. The Christiansen Feature (CF) in the mid-infrared provides a mineralogically grounded proxy for the abundance of SiO2. Here, we present a new experimental cal...

Plasma proteomes of obesity and allometric body shapes in the EPIC cohort

Abstract General obesity (high body mass index, BMI) affects circulating proteins. Obesity-related outcomes, however, differ by body shape but waist and hip circumferences cannot distinguish abdominal from general obesity. We therefore used the allometric body shape index (ABSI),...

Phospholipase D2 acts upstream of PI4P 5-kinases in the response of neurons to extracellular viscosity

The formation of an axon during neuronal differentiation is determined by the competition of positive and negative signals that promote and inhibit extension, respectively. Several biochemical signals have been identified that promote axon extension, but it is just beginning to b...

Grassland destruction causes shifts in plant traits that persist during recovery

Old-growth grasslands assemble over millennia and support high biodiversity and many ecosystem services, but continue to undergo widespread destruction for production of crops, timber, and minerals. How biodiversity recovers after grassland destruction and the functional conseque...

Observers exhibit greater caution and faster evidence accumulation when identifying joint versus individual actions

Coordination requires anticipating and adapting to others' actions in real time. While research has shown that observers predict observed solo actions, little is known about how predictive processes change when observing joint actions. We tested whether, for joint actions, observ...

Microstructural insights into fast ion transport in solid electrolytes via multiscale modeling

Abstract Improving solid electrolytes is critical for high-performance all-solid-state batteries, yet the microstructural features that enable fast ion transport remain poorly understood. Here, we use multiscale modeling to resolve polycrystalline ion transport from atomic-scale...

Reversible Switching due to Attraction and Repulsion: Clusters, Gaps, Sorting, and Mixing

Abstract. We describe a phase transition in continuum limits of interacting particle systems that exhibits a vertical bifurcation diagram. The transition is mediated by a competition short-range repulsion and long-range attraction. As a consequence of the transition, infinitesima...

Transport of cytotoxic cyanine dyes coupled to siRNA into hematopoietic cancer cells with CD20-, CD22- or CD33-targeting ELART nanocarriers

Abstract The efficient and safe transfection of hematopoietic cells is a major hurdle that limits efficacy of therapeutic approaches like RNA-interference. We therefore used our modular EL ectrostatic A ntibody si R NA T argeted therapy platform (ELART) to develop nanocarriers de...

Disequilibrium between chloroplast proton motive force and ATP levels in Arabidopsis

Abstract Current dogma holds that CO 2 fixation by photosynthesis requires additional ATP production via PGR5-dependent cyclic electron transfer (PGR5-CET) to augment the NADPH and ATP produced by linear electron transfer (LET). Here we use the MgATP 2− fluorescent biosensor ATea...

Up and Downthe Hill-Plot: Hydrides of CeGe–Structureand Magnetism

Abstract The hydrogenation behavior of FeB type CeGe was investigated. Hydrogenation (deuteration) produces mixtures of two modifications, similar to hydrides of other FeB type phases LnTt (Ln = La, Ce, Nd; Tt = Si, Ge). P-CeGeD0.75(2) (Pnma, a = 8.1603(5) Å, b = 4.0938(3) Å, c =...

HydrogenBonding Networks Formed by Hydroxyl-FunctionalizedN-Heterocyclic Carbenes on Ag(111)

Abstract N-Heterocyclic carbenes (NHCs) have emerged as robust alternatives to thiols for metal-surface functionalization, offering strong σ-donor character, high thermal stability, and tunable molecular design. Despite advances in NHC surface engineering, the formation of ordere...

The transcription factor NF-Y promotes myeloid cell survival and protects from inflammatory vascular disease

Abstract Background Myeloid cells orchestrate vascular inflammation through transcriptional programs that regulate their maturation, effector function, and survival. While lineage-determining transcription factors establish myeloid identity, understanding of the transcriptional r...

A joint geophysical-geochemical deep-mantle zoning map beneath East Africa and the Indian Ocean

Geochemical signatures of hotspot lavas suggest that their mantle sources are compositionally distinct, but their source locations remain elusive. Mapping hotspots to their deep origins is complicated by the presence of interconnected, low–seismic velocity networks in the mantle,...