University of Münster

Changes in retinal layer thickness during and after pregnancy in a healthy Caucasian cohort

Purpose Structural retinal changes have been reported in pregnant women compared with non-pregnant controls, yet longitudinal optical coherence tomography (OCT) data across pregnancy and postpartum are limited. This prospective study quantifies retinal OCT metrics in healthy preg...

Hydroalkylation and hydroacylation of trifluoromethyl olefins by N-centered direct hydrogen atom transfer photocatalysis

The selective functionalization of trifluoromethyl olefins, while keeping the essential trifluoroalkyl moiety intact, remains a synthetic challenge. In this study, we report the use of an acridinium amidate as a direct hydrogen atom transfer (d-HAT) photocatalyst for the mild and...

Supporting AI Readiness Through Digital Workflows in Materials Science

Materials science produces heterogeneous data across experiments, simulations, and industrial processes that often remain bound to local formats, manual procedures, and project‐specific software. Digital workflows address this fragmentation through explicit, repeatable, and machi...

Diagnosing autoimmune encephalitis in psychiatry: clinical recommendations and unresolved challenges from the GENERATE network

Psychiatric syndromes can be caused by underlying autoimmune encephalitis (AE). This represents a diagnostic challenge at the interface of psychiatry and neurology. While AE mostly manifests with a combined, complex neuropsychiatric syndrome, some patients with AE may (initially)...

Transposable elements as evolutionary catalysts of ant macrodiversity

Transposable elements (TEs) are key contributors to genome evolution, yet their macroevolutionary roles in adaptive radiations remain poorly understood, as high-quality genomic resources at sufficient phylogenetic breadth and appropriate comparative methods have been lacking. Her...

Cohesion Policy and Economic Growth in EU Regions

Abstract EU Cohesion Policy (CP) absorbs roughly one-third of the EU budget. This article reviews the causal evidence on the effects of CP on the economic growth and convergence of EU regions. The verdict is positive but modest: GDP multipliers are around one euro of output per e...

Thermal conductivity of carbon nanotube-filled diblock copolymer composites

We investigate the influence of microphase-selective localization and aggregation of carbon nanotubes (CNTs) on the thermal conductivity of CNT-filled symmetric diblock copolymer (DBC) composites. A phase-field description of the DBC morphology is combined with Monte Carlo simula...

Future GLP-1 receptor co-agonists and their cardiac effects

Agonists at glucagon-like-peptide-1 receptors (GLP-1R) are becoming approved drugs to treat not only type 2 diabetes and obesity but also cardiac diseases such as coronary heart disease, myocardial infarction and heart failure. Agonism at the GLP-1R can be combined with agonism a...

Contractile effects of Aficamten in the human atrium

Abstract Aficamten is an approved drug to treat hypertrophic cardiomyopathy. Aficamten desensitizes bovine myofilaments against calcium cations. In isolated animal cardiac preparations, aficamten reduced force of contraction (FOC) but its effects on isolated human cardiac prepara...

Accelerated erosion of the Eastern European Alps since ~ 3 Ma: a response to climatic cooling?

Global cooling and repeated glaciations during the late Cenozoic are inferred to have altered the topography of many mountain belts by enhancing the rates of erosion and valley incision. However, quantifying these changes in erosion rate and local relief has proven challenging. I...

Diboron‐Embedded Heteroacenes With Systematically Varied Central π‐Skeletons and Fusion Modes

ABSTRACT Diboron‐embedded heteroacenes with systematically varied central π‐skeletons and fusion modes were synthesized via one‐pot cyclative borylation using benzene, thieno[3,2‐ b ]thiophene, or dithieno[3,2‐ b :2′,3′‐ d ]thiophene cores, affording six derivatives with C 2h or...

Supercritical Fluid Chromatography for Expedited Sample Clean‐Up in Isotope Ratio Mass Spectrometry Including Cholesterol as New Endogenous Reference Compound

ABSTRACT Doping control samples showing elevated urinary concentrations and concentration ratios of testosterone or testosterone metabolites are forwarded to isotope ratio mass spectrometry‐based determinations in order to differentiate between naturally elevated concentrations a...

Psychotherapy remission prediction models show limited cross-clinic generalizability in routine outpatient care

Abstract Clinical prediction models for psychotherapy outcomes have the potential to assist therapists in planning a patient’s individual treatment, but their clinical utility depends on maintaining predictive performance across settings. We assessed prediction of post-treatment...

Borosulfates Hosting Se 4 2+ Ions—Crystal Structures, Chemical Bonding, Optical Spectroscopy, and Magnetism

ABSTRACT Despite consistent growth in the number of compounds known to host homo‐ and hetero polycations of group 16 elements, only two, Se 4 [HS 2 O 7 ] 2 and Se 4 [S 4 O 13 ], provided an exclusively oxidic coordination environment, the former being the first structural charact...

A conceptual model and supporting approach for EU taxonomy alignment with green BPM

Abstract Increasingly, companies are obliged and incentivized through regulations to consider the impact of their business processes on the environment, in order to promote sustainable business practices. In particular, the EU Taxonomy for Sustainable Activities outlines criteria...

Not my democracy: conceptions, discontent, and participation in Europe

Abstract Citizens differ not only in how strongly they support democracy, but also in what they expect democracy to be. Yet we know less about whether these democratic expectations shape satisfaction with democracy (SwD) and, through it, political participation (PP) in establishe...

Evidence for early and late prediction error-associated ERP responses during probabilistic cueing

Probabilistic relationships are omnipresent in our sensory environment. According to some predictive coding models, the processing of deviations from expectation should be accompanied by enhanced neuronal responses, reflecting a prediction error, while expected stimuli should lea...

Microglia and border-associated macrophages play opposite roles in cerebrovascular and leukocyte responses under systemic inflammation in male mice

Microglia closely associate with the vasculature, but their roles in leukocyte trafficking and cerebral blood flow (CBF) during systemic inflammation are unclear. We show that sustained systemic inflammation leads to altered microglia-vascular interactions, leukocyte recruitment...

The detrital zircon Hf and O isotope signals recorded in Paleozoic Saxothuringian clastic rocks of Germany: insights into the Eburnean and Cadomian orogenies

Saxothuringian sandstones of the Armorican Terrane Assemblage reflect a dichotomous detrital zircon age provenance signal representing the Eburnean Orogeny on the West African Craton (2200–2000 Ma) and the Cadomian Orogeny of northern Gondwana (750–540 Ma). We present O isotope d...

Photo-guided azopolymer hydrogel actuators

Amorphous azopolymers are fascinating materials that can be deformed in arbitrary directions by light. However, they are so far used mostly for microfabrication, to anisotropically reshape dry polymer structures - essentially as a post-processing fabrication step. This is because...