University of Lausanne

Family migration and gender inequality in housework: Evidence from China

While the impact of family migration on paid work is well-documented, its potential influence on housework remains largely unknown. This study examines the effect of couple migration on the division of housework in China, focusing on changes in housework hours for both female and...

A validated amplicon panel for parentage reconstruction and selection monitoring in whitefish (Coregonus spp.)

Abstract Fish populations are notoriously difficult to monitor because their aquatic habitats limit observation. While physical or chemical tagging (e.g., adipose fin removal or Alizarin Red S staining of bones) can reduce growth or survival or requires sacrifice, genetic tools o...

Early Introduction and Prolonged Full‐Dose Anakinra Reduce Recurrence Risk After Discontinuation in Recurrent Pericarditis: An International Multicenter Cohort

Background Anakinra is effective in recurrent pericarditis, yet optimal treatment duration and strategies for safe drug discontinuation remain uncertain. Identifying predictors of sustained remission after discontinuation is important for clinical management. Methods We retrospec...

Design and validation of a GMP-compliant manufacturing platform of extracellular vesicles from mesenchymal stromal cells

There is growing interest in mesenchymal stromal cell-derived extracellular vesicles (MSC-EVs) as key components in the development of next-generation regenerative cell-free therapies; however, their clinical translation remains limited by a lack of validated clinical-grade manuf...

Airflows redefine the cost of aerial transport in the wild

Fuel economy matters to both animals and machines, as the cost of transport can determine where, when, and how far locomotion is possible. However, established estimates of these values for animal flight come from laboratories and treat the atmosphere as constant, even though fre...

The Relationship Between a Wildlife Conservation Project Involving Scientist-Farmer Collaboration and Farmers’ Attitudes and Behaviors Towards Conservation Science and the Environment in Switzerland

Considering agriculture’s significant contribution to the environmental crisis, farmers play a crucial role in conservation. It is thus important to explore the drivers motivating them towards sustainable practices. Farmer-scientist collaboration is a promising tool to promote pr...

Chronic alanine aminotransferase elevation in people with HIV : Time trends over 22 years and genetic predisposition

Abstract Introduction Chronic elevation of alanine aminotransferase (cALT) is common in people with HIV. Published reports on cALT prevalence time trends have not been uniform. It is unknown whether genetic background is associated with cALT in people with HIV. Methods cALT was d...

Why don't all birds lay early? Causes and consequences of breeding timing for a long‐lived migratory seabird

The relationship between earlier laying and higher breeding success is well-established in avian species. However, a wide distribution of breeding timings is often maintained within a population, and the causes and consequences of this variation require further exploration, parti...

Dispersal diversity buffers species vulnerability to local extinction

Abstract Predicting species persistence within ecological communities is a fundamental challenge for both empirical and theoretical ecology. Existing methods span from mechanistic models, whose parameters are difficult to estimate from data, to statistical tools whose context-spe...

Limited global awareness of invasive alien species and little support for their management

Invasive alien species (IAS) are one of the main drivers of global change and can cause a wide range of negative ecological and social impacts. Addressing these impacts requires management actions, which can fail to be effective when not supported by the public. Here, we conducte...

Antarctic sea ice over the past 130 000 years – Part 2: A review of its role in the Earth system

Abstract. Antarctic sea-ice cover reached historically low levels in 2023, consistent with the simulated decrease in sea-ice extent in response to anthropogenic warming. Antarctic sea ice is closely linked to multiple components of the Earth system, thus its demise could precipit...

Exploring feature variability in digitally captured signatures—Part II : Discrimination between genuine and simulated signatures and the effects of collection sessions and writing position

Abstract This study investigated the discrimination between genuine and simulated digitally captured signatures (DCSs) to support their forensic examination. The dataset included genuine questioned signatures from 65 writers, collected across multiple sessions and in three writin...

The local networks of Swiss banking elites: from embeddedness to disengagement, 1890–2020

This visualisation examines the changing local networks of Swiss banking elites between 1890 and 2020. Drawing on data from Switzerland’s three main cities, it reconstructs interlocking directorates linking 301 banking elites to major local institutions. It reveals a long-term sh...

BET inhibition induces coordinated repression of the stem cell-related HOX signature in GB uncovering an epigenetic vulnerability

Abstract Background Glioblastoma (GB) is the most aggressive primary brain tumor, characterized by therapy resistance, attributed to a multitude of epi-genetic changes resulting in phenotypic plasticity with altered cell states. To uncover druggable epigenetic vulnerabilities, we...

Cutaneous Lymphoma International Prognostic Index and Risk Stratification in Advanced Mycosis Fungoides and Sézary Syndrome

Importance Risk stratification in advanced mycosis fungoides and Sézary syndrome (MF/SS) remains suboptimal given that current TNMB (tumor, node, metastasis, blood) staging has limited prognostic value for clinically relevant outcomes. Objective To determine whether the Cutaneous...

MOSAIC: Intra-tumoral heterogeneity characterization through large-scale spatial and cell-resolved multi-omics profiling

Understanding the tumor microenvironment has the potential to significantly advance precision oncology, but this effort has been hampered by the scarcity of consistent large data sets. Here, we introduce MOSAIC (Multi-Omics Spatial Atlas in Cancer), a multi-center clinical omics...

Infiltration between the popliteal artery and the capsule of the knee ( IPACK ) vs. selective tibial nerve block for analgesia after anterior cruciate ligament reconstruction: a randomised controlled trial

Summary Introduction Infiltration between the popliteal artery and the capsule of the knee (IPACK) and the selective tibial nerve block both provide analgesia for the posterior aspect of the knee after anterior cruciate ligament reconstruction. This randomised controlled triple‐b...

Simultaneous T 1 and T 2 Mapping in the Brain With QuantoRAGE : An MP2RAGE Variant Using T 2 ‐Prepared Inversion

ABSTRACT Purpose To develop and validate a repeatable and reproducible approach, QuantoRAGE, for simultaneous whole‐brain T 1 and T 2 mapping using adiabatic magnetization preparation. Methods QuantoRAGE is a 3D FLASH‐based sequence using an adiabatic T 2 ‐prepared inversion foll...

Information‐Theoretic Framework for Allosteric Communication Pathway Prediction From Protein Structure

ABSTRACT Allosteric communication is fundamental to the function of proteins, but identifying the residue‐level pathways through which signals travel and their directionality is still a major challenge. Here we present a multi‐metric information‐theoretic framework that identifie...

Outcomes of Long‐Term Absorbable Mesh Use for Ventral Hernia Repair in Immunosuppressed Patients

BACKGROUND: Immunosuppressed patients are more at risk of perioperative infections. In case of ventral hernia repair, the use of a long-term absorbable mesh could potentially decrease the infectious risk in these patients. This study aimed to assess the short- and mid-term outcom...