University of Illinois Chicago

Ready or Hesitant? Pediatric Sedation Confidence Among Senior OMS Residents

PURPOSE/OBJECTIVES: To describe self-reported confidence of final-year oral and maxillofacial surgery (OMS) residents in managing pediatric sedation and to explore associated training-related factors. METHODS: A prospective, cross-sectional, multicenter electronic survey was dist...

Fission yeast RPA–TERT–Tpz1TPP1 complex promotes telomere extension and suppresses telomere recombination

Abstract Telomerase maintains chromosome ends by extending telomeric DNA, yet how recruited telomerase becomes productively engaged remains poorly understood. Recent studies found that Replication Protein A (RPA) contributes to telomerase stimulation through interaction with TERT...

Lessons From the Communication Bridge Trials: Advancing Meaningful Dyadic Interventions Toward Implementation

Purpose: This review describes the historical motivations, development, and evolution of the Communication Bridge (CB) research program, which is designed to maximize quality of life and minimize burden for individuals living with dementia and their communication partners. The CB...

Strong minimality of triangle functions

In this manuscript, we give a new proof of strong minimality of certain automorphic functions, originally results of Freitag and Scanlon (2017), Casale, Freitag and Nagloo (2020), Blázquez-Sanz, Casale, Freitag and Nagloo (2020). Our proof is shorter and conceptually different th...

Efficacy of student developed and led high value care education in preclinical medical students

The Institute of Medicine estimates that, on average, about one third of all healthcare waste is attributed to unnecessary services. High value care (HVC) is a proposed solution to this problem but is currently underrepresented in preclinical undergraduate medical education (UME)...

Laser-processed wickless vapor chambers harness phase change to enable forced-air cooling of high-heat-flux electronics

Traditional electronics cooling approaches often employ fins placed directly on top of heat-generating elements (e.g. CPUs or GPUs). While such methodologies are often sufficient to handle general heat loads, they prove insufficient in scenarios that involve smaller hotspots gene...

Targeting Latent Tuberculosis Using Hypoxia-Activated Prodrugs of Bedaquiline Analogues

Abstract The increasing emergence of antimicrobial resistance (AMR) is reducing the effectiveness of existing antibiotics against bacterial infections, including tuberculosis (TB), a deadly disease caused by Mycobacterium tuberculosis (M.tb). Approximately 90% of infected individ...

Beyond Planar Graphene: Roughness‐Conforming Microlaminates Enable Superior Heat Removal

ABSTRACT The escalating cooling demands of high‐heat‐flux electronic systems require materials that deliver efficient heat spreading, phase‐change enhancement, and scalable manufacturability—capabilities rarely found simultaneously on a single platform. Here, we introduce a micro...

Feasibility and Operator-Reported Utility of Transesophageal Lung Ultrasound As an Adjunct to Resuscitative Transesophageal Echocardiography in the Evaluation of Shock: A Multicenter Observational Study

Objectives: To describe the utilization, feasibility, and operator-reported diagnostic and management impact of transesophageal lung ultrasound (TELUS) integrated into resuscitative transesophageal echocardiography (TEE) for the assessment of mechanically ventilated adults with s...

Artificial Intelligence for Diabetic Retinopathy

This Viewpoint discusses artificial intelligence for treatment of diabetic retinopathy.

Immune Checkpoint B7-H3 Inhibition Reprograms Acute Neuroinflammation and Protects the Brain After Acute Ischemic Stroke

BACKGROUND: The role of immune checkpoint B7-H3 in acute ischemic stroke prognosis and poststroke immunosuppression remains uninvestigated, despite the clinical significance of immune checkpoints with inflammaging and poststroke infections. In this study, we investigated the effe...

Neurobiological and Neuroimmune Mechanisms Linking Chronic Pain, Sleep Disturbances and Mental Health Disorders

Chronic pain, sleep disturbances, and mental health disorders such as anxiety and depression disorders frequently co-occur, forming a self-reinforcing cycle that impairs daily functioning and quality of life. Chronic pain is driven by peripheral and central sensitization, the lat...

ORCHA: A performance portability system for extreme heterogeneity

Heterogeneity is the prevalent trend in the rapidly evolving high-performance computing (HPC) landscape in both hardware and application software. The diversity in hardware platforms, currently comprising various accelerators and a future possibility of specializable chiplets, po...

Superlarge-Bore Versus Large-Bore Aspiration Catheters in Mechanical Thrombectomy: A Multicenter Propensity-Matched Analysis

BACKGROUND AND OBJECTIVES: Aspiration catheters are an integral component of mechanical thrombectomy for acute ischemic stroke (AIS). Following early series demonstrating increasing procedural efficiency and improved outcomes with use of large-bore (LB) aspiration catheters, ther...

Artificial intelligence literacy among U.S. rural medical education students: perceptions, readiness, educational needs, and barriers

Artificial intelligence is increasingly integrated into healthcare. However, formal training in medical education remains limited, especially among Rural Medical Education students. This study examined students’ perceptions of artificial intelligence, their readiness to use it, t...

Metabolic Signatures Associated with COVID-19 Vaccination in Serum from Healthy Individuals

Background: COVID-19 vaccines have proven effective in reducing severe disease and mortality from SARS CoV-2 infection. The underlying molecular mechanisms and alterations in the human serum metabolome influencing the effectiveness and development of immunity remain unclear. Meth...

Utilization of the Functional Lower Extremity Evaluation (FLEE) in Return-to-Sport Rehabilitation Protocol Following Hip Arthroscopy in Collegiate Athletes: A Case Series

Background The Functional Lower Extremity Evaluation (FLEE) is a validated assessment tool designed to assess lower limb function and symmetry. There is a gap in knowledge in return to sport (RTS) regarding the application of the FLEE in RTS rehabilitation protocols following hip...

An Experience-Sampling Approach to Examining Cortisol and Testosterone Profiles in Bipolar and Depressive Mood Disorders

Emotion dysregulation is a core component of bipolar disorder (BD). However, there is a critical gap concerning the measurement of emotion-relevant neuroendocrine processes in this population. The present investigation examined neuroendocrine profiles (i.e., cortisol and testoste...

Evaluation of a community-based education program on maternal and child health needs in a semi-urban locality: a university-community partnership pilot project in Lahore, Pakistan

Pakistan faces high maternal and child mortality rates, with semi-urban and rural areas particularly affected. Community-based initiatives that emphasize local participation can address these challenges by fostering community ownership and sustainability. This study evaluated a c...

The Theological Poetics of Pauline κένωσις in Patristic Authors: A Dialogue with Michael C. Magree ☆

Abstract This review engages in dialogue with Magree's methodological assumptions (literary, rhetorical, philosophical and theological) and approach to the history of reception of this critically important Pauline passage (Philippians 2:7) and then provides a critical assessment...