University of Gothenburg

Atlas of cell types and regulatory elements underlying human facial diversity

Abstract Human genetic diversity generates an astonishing variety of facial shapes, and craniofacial anomalies rank among the most common birth defects. Identifying the cellular mechanisms that mediate the genome’s influence on facial variation remains a challenge. Here we create...

Screening of Brazilian Isolated Yeasts Reveals Multiple Potential Chassis for Industrial Biotechnology

ABSTRACT The future of sustainable industrial biotechnology relies on microbial hosts that can thrive where conventional strains fail. Although Saccharomyces cerevisiae remains the dominant industrial yeast, its metabolic constraints and stress sensitivity highlight the need for...

Strengthening systems to monitor antibiotics. An action oriented approach

Background Antibiotics have become lynchpins of our modern systems of healthcare, animal health and agriculture. Monitoring the types and volumes of antibiotics distributed, used and discharged across these systems is critical to provide evidence for action. With limited resource...

Science-driven or engagement-driven? Shaping commercialisation pathways in public research organisations

This paper analyses how scientists’ commercialisation pathways differ depending on how researchers balance two distinct orientations towards advancing science: an orientation to expand the pool of scholarly work (science-driven orientation) and an orientation to achieve practical...

Meta-ethnography and policy effectiveness: an Evidential Pluralism perspective

Abstract Evidence-based policy is typically grounded in a narrow conception of evidence, one that prioritises comparative studies and quantitative meta-analyses as the preferred base for establishing causal claims. However, this prevailing theory of evidence—often implicitly adop...

Efficacy of HER2-targeted therapy in early breast cancer 2008–2020 in Sweden in the real-world setting

Abstract Large-scale real-world evidence on outcomes in HER2-positive (HER2 +) early breast cancer (EBC) remains limited. We investigated overall survival (OS) and its prognostic factors in patients with HER2+ EBC. We here analyzed data from 4,638 patients with HER2 + EBC diagnos...

Combined effects of long‑term air pollution exposures on adult active asthma: a quantile g-computation analysis

Abstract Background Air pollution is a well‑established risk factor for the development of asthma, yet most studies examine pollutants individually, failing to capture the health effects of real‑world pollutant mixtures. Assessing long-term multipollutant exposure is essential fo...

Sexual and gender minority parents’ experiences of lactation: a meta-ethnographic review

Abstract Background Although lactation has been widely studied, existing evidence largely reflects heterosexual and cisgender parents’ experiences. Sexual and gender minority (SGM) parents may face distinct embodied, social, and healthcare-related factors that shape lactation and...

A New Product Formula for $$(z;q)_\infty $$, with Applications to Asymptotics

Abstract We express the q -Pochhammer symbol $$(z;q)_\infty $$ ( z ; q ) ∞ as an infinite product of gamma functions, analogously to how Narukawa expressed the elliptic gamma function as an infinite product of hyperbolic gamma functions. This identity is used to obtain asymptotic...

Case-based pharmacotherapeutic learning structured around the prescribing optimization method and the WHO 6-step model: Medical students’ views from an exploratory questionnaire study

Abstract Purpose Pharmacotherapy is a core competence for physicians and case-based learning is a valuable teaching method for developing this competence. This study explored medical students’ views on structuring pharmacotherapeutic education around either the Prescribing Optimi...

Smoking behaviours and attitudes among dental students in three European countries: a multicentre cross-sectional study

Tobacco use remains a major public health concern and a significant risk factor for systemic and oral diseases. Dental students, as future healthcare professionals, are expected to play an important role in tobacco control and smoking cessation. This multicentre study aimed to as...

Beyond the gold standard: evaluating AI for subject indexing of Swedish LGBTQ + fiction

Purpose This study evaluates the potential of large language models (LLMs) for subject indexing of Swedish LGBTQ + fiction using the dedicated QLIT thesaurus, based on Homosaurus. It examines both the quantitative performance and qualitative characteristics of AI-generated subjec...

Studying Physical–Virtual Hybridisation in Everyday Life Through the Time‐Geographic Project Concept

Abstract This study proposes a time‐geographic approach for operationally defining and quantitatively measuring the physical–virtual hybridisation of daily activities. While hybridisation has been proposed to move beyond separating the usage of information and communications tech...

The politics of restricted inclusion: a longitudinal policy analysis of healthcare access for people living as undocumented migrants in Sweden

This study examines how healthcare access for people living as undocumented migrants has been constituted, contested, and reconfigured in Sweden from the early 1990s to the mid 2020s, challenging institutionalist claims that universalist welfare systems reliably generate solidari...

Teachings of Demons in Later Times (1 Tim 4.1–5)

Abstract In this short study, the syntactic structure of 1 Tim 4.1–3a is re-examined to address long-standing interpretative challenges regarding its apocalyptic warning against demonic teachings. A traditional reading of the passage, as reflected in many translations and comment...

Sex and age at exposure influence 131I biodistribution and dosimetry in Sprague–Dawley rats

Abstract Background Assessing the biodistribution and absorbed dose of ¹³¹I is crucial for optimisation of radionuclide therapy, as well as for improving risk assessment following nuclear emergencies. After the Chernobyl accident, an increase in thyroid cancer among children was...

Ultra-fast spin Hall nano-oscillator based microwave spectral analysis

Abstract Ultra-fast spectrum analysis based on rapidly tuned spintronic nano-oscillators has been under development for the last few years and has already demonstrated promising results. Here, we demonstrate an ultra-fast microwave spectrum analyzer based on a chain of five mutua...

Health co-benefits of sustainable dietary transitions to reduced red and processed meat intake in the United Kingdom: a modelling study

Abstract Purpose Reducing meat intake and increasing plant-based food consumption are priorities for chronic disease prevention and environmental sustainability across Europe. Previous modelling has outlined how policy interventions could shift dietary patterns to align with meat...

Letting patients lead? Practitioners’ experiences of using DIALOG + in psychosis outpatient care – patient involvement, collaborative dynamics, and professional roles

Abstract Background Severe mental illness, such as psychosis, significantly affects many areas of life. Involving patients in their care may enhance engagement and support recovery by ensuring that treatment focuses on their expressed needs. DIALOG + is an intervention, supported...

How digital portfolios become governable: a venture design research study of public sector digital development

Purpose Public sector organizations increasingly struggle to govern digital development in a coherent and strategic manner. This paper aims to examine how governance of digital development can be actively specified through the design of a digital solution, rather than merely supp...