University of Freiburg

Network meta-analysis and diffusion

We show that the covariance matrix of the treatment effect estimates in a network meta-analysis can be obtained without matrix inversion using a geometric series of diffusion matrices. This property extends to the hat matrix and provides a connection between parameter estimation...

NMSSMScanner: Efficient scans in the NMSSM parameter space proof of concept

We present the first version of the new scanning tool NMSSMScanner that allows to perform efficient scans in the complex multi-parameter space of the Next-to-Minimal Supersymmetric extension of the Standard Model (NMSSM) while taking into account all relevant constraints. As a pr...

Responsible agrivoltaics in temperate Europe: Making systems work for plants, people, and climate

Societal Impact Statement Agrivoltaics, the co‐location of solar panels and crops, is increasingly promoted to expand renewable energy without compromising agricultural areas. However, systems that are poorly designed impact productivity, landscape, and ecology, and face public c...

Coordination-Controlled Stability of Pd Single-Atom Catalysts under Electrochemical Conditions

Abstract Single-atom catalysts (SACs) maximize atom utilization and site-specificity for diverse chemical and electrochemical transformations. While activity and selectivity have been optimized through advanced synthetic methods, the electrochemical stability of SACs remains insu...

Synthesis and Polymerization of a Lactone Building Block Derived From Cashew Nut Shells

The biorenewable feedstock cardanol, a phenol compound substituted with an unsaturated C15 hydrocarbon chain, was selectively transformed into a cyclohexanone derivative through partial hydrogenation. Subsequent conversion via Baeyer-Villiger oxidation (BVO) gave a lactone produc...

An Efficient Mixed‐Integer Formulation and an Iterative Method for Optimal Control of Switched Systems Under Dwell Time Constraints

ABSTRACT This paper presents an efficient mixed‐integer nonlinear programming (MINLP) formulation for systems with discrete control inputs under minimum dwell time (MDT) constraints. By viewing such systems as switched systems, the problem is decomposed into a sequence optimizati...

Mass movements in the southern Black Forest, Germany

This dataset provides a geomorphological inventory of 158 mass movements larger than 5000 m² mapped within the Last Glacial Maximum extent of the Late Pleistocene Feldberg ice cap in the southern Black Forest, southwest Germany (48°N, 8°E). The dataset is a zip file that contains...

Forest carbon certification under climate and mortality uncertainty: ecological and economic trade-offs of management scenarios in Freiburg, Germany

Abstract Background Forest carbon certification could help finance the transformation of climate-sensitive stands, but early interventions may reduce biomass and timber revenue before carbon and ecological benefits emerge. Evidence that jointly evaluates forest growth, hydrologic...

Raman Spectroscopy of Laser-Micro-Annealing-Induced Structural Changes in Ti-6Al-4V

This short study presents the results of micro-Raman investigations performed on the alloy Ti-6Al-4V, which was additively manufactured via metal fused filament fabrication (MF3). Local laser micro-annealing was applied at different power intensities to distinct regions. The appl...

Forest management, climate change, and roe deer: A conceptual model of how silvicultural systems shape habitat, population density, and browsing impacts

Management of roe deer in European forests may be challenging due to their impact on tree regeneration and potential negative effects on tree species composition, forest resilience and various ecosystem services including timber production. However, silvicultural practices themse...

Fine Tuning of Thermal Activation and C,H-Insertion Crosslinking of Phenyl Diazo Ester Polymers

Abstract We describe the synthesis and crosslinking of polymers containing substituted phenyl diazo ester moieties. The diazo groups, which are dormant at room temperature, can be thermally activated to generate carbenes by releasing nitrogen. This subsequently causes C−H inserti...

Prognosis of acute symptomatic seizures and impact of prolonged treatment with anti‐seizure medication

Abstract Objectives Acute symptomatic epileptic seizures (ASySs) occur in temporal proximity to acute brain insults. Given their low risk of subsequent unprovoked seizures, current guidelines recommend either no treatment with anti‐seizure medication (ASM) or early discontinuatio...

The ECOSENSE forest: a distributed sensor and data management system for real-time monitoring of ecosystem processes and stresses

Abstract. Forests provide crucial ecosystem services, but are vulnerable to climate-related physical and biological stresses, such as droughts, pests and pathogens. The rapid climate change currently observed increases the pressure on forest ecosystems, with already drastic conse...

One‐Step Access to Ultra‐Bright Macrocyclic Oligo‐BODIPYs Featuring Long‐Lived Cyclic Excitons

ABSTRACT The controlled organization of chromophores into defined assemblies with collective photophysical properties is a key concept for natural and artificial photonic systems. A template‐free, one‐step synthesis affords a series of methylene‐bridged macrocyclic oligo‐BODIPYs...

Remote sensing and deep learning for standing dead-tree detection and mapping: a review of advances, challenges, and future directions

Standing dead trees are visible indicators of tree mortality and an important transitional component linking forest disturbance to future lying deadwood, habitat availability, and carbon storage. As drought, insect outbreaks, pathogens, and climate extremes intensify tree mortali...

Data driven approach to identify vulnerable plaques in carotid atherosclerosis using computed tomography imaging and computational fluid dynamics: A pilot study

The current clinical gold standard for identifying vulnerable plaque is plaque Magnetic Resonance Imaging (MRI). However, owing to its limited availability, many patients do not have access. This pilot study aims to explore whether computational fluid dynamics (CFD) modelling, es...

Agreement of markerless and marker-based joint kinetics in team sport-specific change-of-direction movements

Abstract Markerless (ML) motion capture is a practical alternative to marker-based (MB) systems, yet its ability to estimate joint kinetics during team sport-specific movements remains unclear. This study evaluated the agreement between ML and MB lower extremity joint moment esti...

Sitagliptin for Acute Graft-Versus-Host Disease Prevention in Alternative Donor Transplantation: A Randomized Phase III Trial

PURPOSE This trial evaluated whether the addition of sitagliptin to antithymocyte globulin (ATG)–based prophylaxis reduces the incidence of acute graft-versus-host disease (aGVHD) after alternative donor hematopoietic stem-cell transplantation. METHODS This prospective, multicent...

Everything you always wanted to know about sleep, but you were afraid to ask: expert concise guide and recommendations on assessing sleep-wake disturbances within a psychiatric context in contemporary times

OBJECTIVE: While disrupted sleep has long been linked to mental disorders there has been a notable decrease in interest and sleep-wake disorders have received low priority in psychiatric care. The aim of the paper was to present a concise guide for evaluating common sleep-wake di...

Organic–Inorganic Dual‐Nanofiber Interpenetrating Network Scaffolds for Complementary Enhancement of Mechanical Stability and Osteogenic Bioactivity

ABSTRACT Incorporating nanofibers into 3D‐printed scaffolds is an effective strategy to enhance the physicochemical properties and osteogenic bioactivity of bone tissue engineering constructs. In this study, we developed a composite scaffold featuring a dual‐nanofiber interpenetr...