University of Colorado System

A trace pairing and Elliott invariant for groupoid homology

Abstract For an étale groupoid, we define a pairing between the Crainic–Moerdijk groupoid homology and the simplex of invariant Borel probability measures on the base space. The main novelty here is that the groupoid need not have totally disconnected base space, and thus the pai...

Engineered Deoxyribonucleic Acid-Tunable Spheroid Platform for Analysis of Tumor-Macrophage Interactions

Abstract Tumor architecture strongly influences immune cell behavior, yet the individual contributions of cell-cell spacing and hypoxia remain difficult to isolate in vivo. Here, we use a DNA-programmable 3D tumor spheroid platform to generate 4T1 spheroids with tunable intercell...

Autoencoder Neural Networks for Representations of Periodic Orbit Families

Traditional methods for parameterizing and storing periodic orbit families use discretized representations of the family. In this work, continuous parameterizations of periodic orbit families in the Earth/Moon system are developed using techniques from machine learning. Autoencod...

Sleep MAPP: a decision support tool for guideline-concordant sleep care in the polytrauma/traumatic brain injury system of care

OBJECTIVE: First, to summarize the development of Sleep MAPP, a decision support tool designed to facilitate guideline-concordant sleep disorder care in the Veterans Health Administration (VHA) Polytrauma/Traumatic Brain Injury System of Care (PSC). Second, to assess usability, a...