University of British Columbia

Frozen Brain-MRI Foundation Models Are Site Fingerprints

Frozen foundation-model (FM) embeddings are increasingly used as off-the-shelf brain-MRI representations, on theassumption that they capture anatomy. We audit what they actually encode and find that acquisition site is a large,intrinsic component of the representation. Across two...

Identifying a Gap in Antiphospholipid Antibody Syndrome Testing in Young Patients with Thrombotic and Obstetric Events

Objectives Antiphospholipid antibody syndrome (APS) is an autoimmune disease characterized by thrombosis and/or certain obstetric complications in the presence of persistent antiphospholipid antibodies (aPL). In previous studies, 17% of patients <50 years old who experienced a...

Telephone versus in-person administration of the Early Childhood Development Index 2030: a crossover study, Brazil, Canada, India and Malawi.

Objective: To examine agreement between telephone and in-person administration of the Early Childhood Development Index 2030 (ECDI2030) survey. Methods: -tests and intraclass correlation coefficients. Findings: : -0.36), regardless of modality. However, pooled and stratified intr...

Moving Equity into Practice: Evaluation of an Online Asynchronous Continuing Medical Education Program for Rheumatology Care

Objectives Persistent health inequities exist in the diagnosis, treatment, and outcomes of rheumatologic diseases among at-risk populations in Canada. Prior research identified barriers and facilitators experienced by at-risk populations in Canada when accessing rheumatology care...

Performance of the 2025 ASAS-Spartan Revised Classification Criteria for Axial Spondyloarthritis in a Canadian Multicenter Inception Cohort with Psoriasis, Uveitis, or Colitis Presenting with Undiagnosed Back Pain

Objectives To test the performance of the 2025 ASAS-SPARTAN Revised Classification Criteria for Axial Spondyloarthritis (axSpA)[1] in a multicenter inception cohort of patients with undiagnosed chronic back pain attending dermatology, ophthalmology, and gastroenterology clinics w...

Dog ownership and healthy brain aging: a pilot study

Background Dog ownership may benefit brain and cognitive health by supporting physical activity and social connectedness, among other mechanisms. Studies that include brain health outcomes ( e.g. , neuroimaging outcomes) are lacking. As the population ages, studies investigating...

Protocol for induction and quantification of injury-primed axon outgrowth in adult mouse DRG neurons

Adult dorsal root ganglion (DRG) neurons provide a powerful model to study axon growth. Dissociated lumbar L3-L5 DRG neurons extend axons de novo in culture, enabling the measurement of baseline outgrowth. Here, we present a protocol for inducing and quantifying injury-primed axo...