University of Bern

Empagliflozin in GSD-Ib: Long-term safety and sustained recovery of neutrophil function including NET formation

Glycogen storage disease type Ib (GSD-Ib) engenders neutropenia and severe neutrophil dysfunction, leading to recurrent infections and inflammatory complications. Recent studies have identified intracellular accumulation of 1,5-anhydroglucitol-6-phosphate (1,5-AG6P) as a key mech...

Physical activity participation in wheelchair sports groups: analysis of individual, interpersonal and club-related characteristics among individuals with physical disabilities

Abstract Background Physical activity is vital for individuals with physical disabilities, yet participation in organized sport remains low even though it significantly promotes physical and mental health, as well as social participation. This study applies a social-ecological mo...

Alignment-free convolutional neural network classification of glycemic states in type 1 diabetes from GC–IMS breath spectra

Abstract Reliable detection of glycemic dysregulation, particularly hypoglycemia, is essential for people with diabetes, yet current approaches rely on capillary blood sampling or require subcutaneous sensor insertion. Breath analysis offers a non-invasive alternative by capturin...

A high-resolution perspective on climate drivers of lake stratification and phototrophic community dynamics in Late Glacial Central Europe

Abstract. Predicting the trajectory of aquatic deoxygenation under global warming requires a mechanistic understanding of lacustrine responses to rapid climate shifts. We investigated how climate-driven changes in catchment vegetation and local iron-rich lithology regulated lake...