Lyon 1 Université

Agreement of Hematologic Measurements Between Jugular and Coccygeal Puncture Sites in Cattle

ABSTRACT Background In bovine medicine, venipuncture is commonly performed at either the jugular or coccygeal vein. Although the coccygeal site is often preferred for practical reasons, sampling sites are inconsistently standardized in scientific studies. It is therefore importan...

Origin of Long‐Wavelength Variations in Crustal Thickness on Rocky Planets

Abstract Long‐wavelength crustal thickness variations are observed on telluric planets, particularly on Mars and the Moon whereas Mercury appears to lack such variations. They may stem from two early‐stage positive feedback mechanisms that can emerge in stagnant‐lid planets. Both...

Early evaluation of the WCT EVI MAP project: implementation, challenges, and emerging impact on evidence-based tumour classification

<ns5:p>Background The WHO Classification of Tumours (WCT) underpins cancer diagnosis globally, but the evidence-base used to inform tumour classification has never been systematically appraised. The WCT EVI MAP project was designed to address this need by developing a structured,...

Imaging in France: 2026 Update

France has seen significant advancements in radiology in recent years, driven by innovations in research and clinical practice. French groups have developed innovative imaging techniques and artificial intelligence applications in the field of diagnostic imaging and interventiona...

The top 10 priorities in palliative care research in France: final results of the AXEPRO study

Prioritizing research is essential to reduce waste, particularly in palliative care, a field with historically limited investment. To identify and rank the top 10 unanswered palliative care research questions in France according to patients, caregivers, healthcare professionals a...

Experimental causal inference from measurements alone in the presence of spatial and temporal quantum correlations

The causal structure of a set of events specifies which events influence which others. Determining this structure, known as causal inference, is a fundamental task in science. Reset-style intervention is commonly used to determine causal structure in classical scenarios. However,...

Simultaneous versus Sequential Cessation of Tobacco and Cannabis: Preferences of Young Adults Who Co‐Use in France

ABSTRACT Introduction Co‐use of tobacco and cannabis is common among young adults and is associated with higher dependence and quitting difficulties. Little is known about the preference for simultaneous or sequential dual cessation in this population. We aimed to explore prefere...

An N-terminal CDC42 T43I variant reveals the mechanism of pyrin inflammasome activation

Heterozygous carboxyl-terminal variants in the RHO guanosine triphosphatase (GTPase) CDC42 are known to cause severe autoinflammatory syndromes. Here, we identified a heterozygous amino-terminal p.T43I (Thr 43 →Ile) CDC42 variant in patients with autoinflammation and uncovered a...

Meltwater transport and mixing-layer growth near the ice–ocean interface

Ice melting into saline water plays a fundamental role in the dynamics near the ice–ocean interface in polar oceans. The physics of meltwater transport involves a non-trivial interplay between the thermodynamics at the interface, hydrodynamic transport in the bulk and the propert...

Microencapsulation of Araucaria angustifolia bract extract: protection and bioaccessibility of phenolic compounds in chitosan-based systems

Abstract Purpose Native to South America, Araucaria angustifolia bracts (an underutilized by-product of seed processing) account for nearly 80% of the pinecone and are commonly discarded. The lyophilized aqueous extract obtained from these residues is rich in phenolic compounds (...

Effects of a virtual reality hypnosis intervention on chronic pain: a user experience and proof-of-concept study

<title>Abstract</title> Chronic pain is a significant public health issue in Canada, with approximately one in four Canadians over the age of 15 living with this condition. Due to its impact on individuals—both physically and psychologically—and its financial burden on the health...

STABILOOP, a cohort trial to assess automated insulin delivery in the management of patients living with type 1 diabetes who are eligible for islet transplantation

A limited subset of people living with type 1 diabetes (T1D) is affected by extreme glycemic lability and frequent unpredictable severe hypoglycemia, significantly impairing quality of life and associated with higher morbidity, mortality, and healthcare costs. Islet transplantati...

Contribution of One‐Electron Oxidation of Purine and Pyrimidine Bases to the Photo‐ and Radiation‐Induced Damage to Cellular DNA

One‐electron oxidants that include type I photosensitizers, biologically relevant carbonate anion radical generators, and high intensity UVC nanosecond lasers are able to ionize in aqueous solution purine and pyrimidine nucleobases. The survey is aimed at critically reviewing the...

No gender differences in predictive processing

Abstract Statistical learning, defined as the implicit extraction of environmental regularities, is considered a fundamental cognitive mechanism that supports predictive processing across individuals, domains, and species. However, whether it is modulated by gender remains unclea...

Vancomycin optimised dosing regimens for critically ill patients receiving renal replacement therapy

Optimal dosing of vancomycin in critically ill patients receiving renal replacement therapy (RRT) is uncertain due to high pharmacokinetic variability. We aimed to develop individualised vancomycin dosing recommendations that optimise efficacy while minimising toxicity. Prospecti...

The Orbitofrontal Expansion for Extending Nasoseptal Flap Reach in the Frontal Sinus

Abstract Skull base defects involving the superior and lateral posterior table of the frontal sinus are challenging to reconstruct due to limited surgical access and restricted reach of available reconstructive options. External approaches are often required, increasing morbidity...

Optimizing Voice-Based Feature Engineering and Machine Learning Pipelines for Early Parkinson’s Disease Detection

Most voice-based Parkinson’s disease studies evaluated a narrow set of models on fixed feature spaces, which limited generalizability and obscured feature–model synergies. Many also neglected fold-wise fitting and runtime measurement, increasing the risk of data leakage and hinde...

Pancreatic panniculitis as the sole manifestation of pancreatic ductal adenocarcinoma: a case report

Pancreatic panniculitis is a rare form of lobular panniculitis characterized by subcutaneous fat necrosis occurring at cutaneous sites distant from the pancreas. It is most often associated with pancreatitis, while pancreatic malignancies — dominated by acinar cell carcinoma — re...