Lyon 1 Université

Biodegradability test on a corn starch based compostable plastic bag: impact of moisture on CO2 emissions, microbial communities, and enzymatic activities

Compostable plastics are often considered as a solution for minimizing plastic contamination due to their biodegradation capacity in composting processes. However, the standards evaluating their biodegradability do not encompass the variability of uncontrolled composting systems,...

Determining a graph from its reconfiguration graph

Given a graph G and a natural number k , the k -recolouring graph C k ( G ) is the graph whose vertices are the k -colourings of G and whose edges link pairs of colourings which differ at exactly one vertex of G . Recently, Hogan et al. proved that G can be determined from C k (...

Silent signals: how bodily cues and age influence speech adaptation

Abstract Do real-time visual cues of listening effort and expectations on the listener's perceived age drive speech adaptations? In experiment 1, young adults read sentences to a listener shown via a head-mounted display. Participants were told their voices were heard under noisy...

Marine‐Derived Type I Collagen From Scyliorhinus canicula : Extraction, Characterization, and Biomedical Applications

ABSTRACT Marine‐derived biomaterials have attracted increasing interest as sustainable and biocompatible alternatives to terrestrial sources. In this study, type I collagen (Coll‐I) was extracted from the skin of Scyliorhinus canicula using an acid‐solubilization method, 7.08% ±...

Patients’ and oncologists’ perspectives on shared decision-making and treatment communication in HR+/HER2 − advanced breast cancer: a multicountry survey

Hormone receptor–positive (HR+), human epidermal growth factor receptor 2-negative (HER2−) breast cancer (BC) represents approximately 70% of all cases. In locally advanced or metastatic stages (laBC/mBC), patients’ quality of life (QoL) often worsens, making shared decision-maki...

Use of cardiac magnetic resonance imaging after hospitalization for acute heart failure: insights from the French nationwide OFICA-2 cohort

Abstract Background Cardiac magnetic resonance (CMR) has a central role in the management of patients with acute heart failure (AHF), but timely access remains heterogeneous. We investigated real-world CMR use in patients hospitalized for AHF and its associations with demographic...

Associations between reduction of hypotension and treatment intensity in hypotension prediction index studies

BACKGROUND: The Hypotension Prediction Index (HPI) is developed for proactive prevention of hypotension and existing meta-analyses report reduced hypotension with HPI-guided management in comparison with a strategy based on MAP alerts of 65 mmHg. Still, validation studies suggest...

Two‐Block Paths in Oriented Graphs of Large Semidegree

ABSTRACT We study the existence of oriented paths with two blocks in oriented graphs under semidegree conditions. A block of an oriented path is a maximal directed subpath. Given positive integers and with , we establish a semidegree function that guarantees the containment of ev...

Targeting Both Oncogenic Signaling and Dependence Receptor Function is Required to Fully Suppress MET Exon 14 Skipping-Driven tumorigenesis

Abstract Receptor tyrosine kinases (RTKs) classically function as oncogenic drivers that promote survival and proliferation upon ligand binding. A subset of RTKs can also function as dependence receptors, inducing apoptosis in the absence of their ligands. Genetic alterations tha...

Antifibrotic therapy in patients with pleuroparenchymal fibroelastosis: a multicentric observational study

Pleuroparenchymal fibroelastosis (PPFE) is a rare interstitial lung disease characterized by upper-lobe predominant pleural and subpleural fibrosis and associated with poor prognosis. No evidence-based medical therapy is currently established, and lung transplantation remains the...

Coupling between statistical learning and interference suppression

Abstract In an ever-changing environment, synchronizing automatic and controlled behaviors is essential for successful adaptation. Yet, the relationship between these behaviors is often debated, partly because of the diverse approaches used to investigate them. The present study...

Longitudinal evidence for decreasing statistical learning abilities across childhood

Abstract Statistical learning enables us to identify patterns in our environment and predict future events, thereby supporting a range of motor, cognitive, and linguistic skills. Despite its significance, the developmental trajectory of statistical learning has remained unclear d...

A Frank-Wolfe-based primal heuristic for quadratic mixed-integer optimization

Abstract We propose a primal heuristic for quadratic mixed-integer problems. Our method extends the Boscia framework – originally a mixed-integer convex solver leveraging a Frank-Wolfe-based branch-and-bound approach – to address nonconvex quadratic objective functions and constr...

Pattern-Anchored Diagnosis of Oral Epithelial Dysplasia: A Position Paper From COST Action INTERCEPTOR Working Group 2

Abstract Purpose Oral epithelial dysplasia (OED) is the principal histopathological marker for malignant risk stratification in oral potentially malignant disorders (OPMDs). Current World Health Organisation (WHO) three-tier and other binary grading systems are limited by modest...

Frequency and laminar profile of feature-specific visual activity revealed by interleaved EEG–fMRI

Abstract The role of cortical oscillations in brain function has been extensively debated, resulting in a variety of theoretical frameworks. Using inter-leaved simultaneous EEG-fMRI, we examined the layer-specific relationship between oscillatory activity and visual processing. W...

Oscillatory Traveling Waves During Visual Entrainment in Autistic and Non-Autistic Adults

Neural oscillations and traveling waves play a crucial role in cognition. In scalp electroencephalography (EEG), waves typically travel along the anterior-posterior axis: forward waves (occipital-to-frontal) predominate during sensory stimulation, while backward waves (frontal-to...

Novel Conductometric Chemosensor Based on Methylenebis(Phosphonic Acid)-Modified Calixarene for L-Arginine Determination

This study reports the synthesis of a novel methylenebisphosphonic acid calix[4]arene derivative and its application as a receptor layer in a conductometric chemosensor for the highly sensitive detection of L-arginine. The synthesized calixarene contains two methylenebisphosphoni...

Early mechanical changes of limb muscle in septic shock assessed by dual-plane shear-wave elastography

Abstract Background Septic shock induces skeletal muscle wasting and neuromuscular dysfunction, contributing to ICU-acquired weakness (ICUAW) and poor recovery after critical illness. Conventional ultrasound primarily captures structural changes but provides limited insight into...

Design and analytical validation of Nexthyro 2.0, a custom next-generation sequencing panel integrating DNA mutation profiling and RNA fusion detection for routine thyroid pathology specimens

Abstract The increasing role of molecular testing in thyroid pathology, from the pre-operative stratification of indeterminate fine-needle aspiration (FNA) categories to the management of advanced carcinomas, has prompted the development of institution-specific custom NGS solutio...

Selective culling and the potential persistence of lumpy skin disease in cattle herds: insights from a mechanistic transmission model

Abstract The first epidemic of lumpy skin disease (LSD) in France was detected in June 2025, with a total of 117 outbreaks recorded by the end of the year. This fast-spreading vector-borne disease of cattle prompted the implementation of strict control measures, including total d...