Tongji University

Institutional complexity and entrepreneurial work in grassroots cultural heritage: Evidence from Hanfu entrepreneurship in China

Abstract Cultural heritage entrepreneurship (CHE) often requires entrepreneurs to reconcile authenticity claims with commercial imperatives. This challenge is especially pronounced in grassroots heritage revivals where heritage meanings are contested and cultural authority is une...

Analysis and Considerations to Lessen Visual Clutter: Multidimensional Associations Between Streetscape Visual Clutter and Urban Perceptions in Shanghai

Visual clutter can affect attention, cognitive load, and environmental evaluation, yet streetscape studies often treat visual complexity as a broad construct without distinguishing visual richness from competition among visual features. Shanghai was selected because its dense, he...

Artificial intelligence empowers full-stack histopathological diagnosis and prognosis of renal cell tumor: a multi-center study with external validation

BACKGROUND: The rapid advancement of digital pathology has opened unprecedented opportunities for intelligent diagnosis in renal cell tumor. However, there remains a significant gap in the availability of reliable deep learning models capable of comprehensive kidney cancer detect...

Leveraging Deep Reinforcement Learning to Facilitate the Transition from Knowledge Diversity to Knowledge Creation in Construction Project Teams

Abstract Knowledge diversity is essential for innovation in construction project teams, yet translating it into tangible outcomes remains challenging. Traditional management theories and static methods often fail to provide dynamic solutions. This study addresses the issue throug...

The landscape and plasticity of transposable element expression in an adult stem cell of high physiological and clinical significance

Abstract Transposable elements (TEs) contribute to diverse aspects of stem cell biology, particularly in germline and pluripotent stem cells, which typically exhibit more open chromatin. In human adult stem cells (ASCs), however, a comprehensive framework describing the landscape...

BCL9 inhibition promotes fibroblast lipogenesis by regulating macrophage–fibroblast interactions to attenuate pulmonary fibrosis

Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal interstitial lung disease with an urgent need for novel therapeutic strategies. M2 macrophage-derived TGF-β1 promotes fibroblast myogenesis, contributing to IPF pathogenesis. Targeting macrophage polarization and fibr...

Conformal principal-asymptotic nets: Parametric design and modular construction of elastic gridshells

Current modular design approaches often rely on numerical optimization to satisfy fabrication constraints, which can be computationally intensive and sensitive to initial geometric conditions. This work introduces a parametric design algorithm based on Conformal Principal-Asympto...

Wingtip Vortex Statistics and Multiscale Evolution in Grid-Generated Turbulent Flow

Freestream turbulence (FST) exerts a pronounced influence on the evolution of wingtip vortices through interactions between multiscale vortex structures. In this study, the vortex statistics and multiscale dynamics of an isolated wingtip vortex subjected to three levels of FST ar...

Smart Urban Agriculture in Transition: A Systematic Review of ICT Integration, Applications, and Challenges

This paper systematically reviews the emerging field of smart urban agriculture, defined as the integration of information and communication technologies (ICTs) into food production practices within and around built-up urban areas. Although urban agriculture and digital agricultu...

Detailed study of non-equilibrium characteristics of quasi-neutral TNSA plasmas

In an experiment performed in November 2022 at the petawatt (PW) laser facility at Vega III located in Salamanca-Spain, we have studied the successful production of several radioisotopes using protons accelerated by the Target Normal Sheath Acceleration (TNSA) mechanism (Rodrigue...

Layered double hydroxide-based ROS-scavenging nanozyme hydrogels re-establish osteoimmune-angiogenic coupling for osteoporotic bone repair

Abstract Background Osteoporotic bone defects (OP-BDs) present a significant clinical challenge because of a pathological microenvironment characterized by severe oxidative stress, persistent inflammation, and disrupted metabolic coupling between osteoblasts and osteoclasts. To o...

Structure-based design of peptide inhibitors targeting the SPSB2–iNOS interaction: a computational approach to modulating nitric oxide signaling

Dysregulation of inducible nitric oxide synthase (iNOS) plays a central role in inflammatory diseases, cancer, and neurodegeneration due to excessive nitric oxide (NO) production. Suppressor of Cytokine Signaling Box Protein 2 (SPSB2) is a key negative regulator of iNOS through s...