The University of Texas at San Antonio Health Science Center

Multi-Institutional Data for Faculty Well-Being Improvements Within and Across Medical Schools

Importance Burnout, engagement, and satisfaction vary in prevalence and correlate with organizational performance in US medical colleges. Large-scale improvements have been elusive. Objective To quantify rates of well-being and its organizational correlates so to help identify op...

Promoting Employment Participation for People with Mental Health Challenges through Photovoice Exhibits: A Survey Study

Date presented: April 25, 2026 Primary Author and Speaker: Jennifer Ruiz-Sandoval, jennifer.m.ruiz14@outlook.com

Geographic Differences in Rehabilitation Delays for Older Adults Across Rehabilitation Service Areas During the COVID-19 Pandemic

Date presented: April 24, 2026 Primary Author and Speaker: Snaghun Nam, nams@uthscsa.edu

Impact of Extent of Surgical Resection on Survival in Patients With High-risk Neuroblastoma

Objective: The impact of extent of resection of the primary tumor on outcomes in patients with high-risk neuroblastoma (HRNB) remains uncertain. We evaluated this issue in patients with HRNB treated on a prospective trial of multimodality therapy. Summary of Background Data: Pati...

ERX 208 induces endoplasmic reticulum stress and suppresses DNA damage repair to enhance chemotherapy sensitivity

Abstract Ovarian cancer (OCa) remains the most lethal gynecologic malignancy, driven in part by intrinsic and acquired therapeutic resistance to DNA damaging chemotherapies. We previously identified that ERX-208 targets the protein encoded by Lysosomal acid lipase (LIPA) to induc...

Latexin deletion in the bone marrow niche suppresses leukemia via LIFR downregulation and immune activation

Acute myeloid leukemia (AML) is the most common adult leukemia diagnosis. Bone marrow (BM) niche significantly influences the initiation and progression of AML. However, our knowledge about the effect of leukemic niche on leukemia stem cells (LSC) and leukemogenesis is limited. I...

Intracytoplasmic sperm injection utilization relative to reported male factor infertility prevalence and its association with preimplantation genetic testing use: a national clinic-level study

PURPOSE: Intracytoplasmic sperm injection (ICSI) is frequently used in assisted reproductive technology practice beyond cycles with reported male factor infertility (MFI). We conducted a hypothesis-generating clinic-level analysis to characterize the relationship between reported...

Mediating effect of pro-inflammatory cytokines in the association between depression, anxiety, and cardiometabolic disorders in a multiethnic US population

Abstract Neuroinflammation is associated with depression and anxiety risk, both of which demonstrate a bilateral relationship with cardiometabolic disorders. Systemic inflammation was also commonly described in patients with cardiometabolic disorders. It is, thus, unclear whether...

“Gender-based violence is the last thing they will think about”: a qualitative study on multilevel factors affecting gender-based violence screening and response in HIV care, Uganda, 2023

Uganda’s Ministry of Health (MOH) adopted the World Health Organization’s guidelines to incorporate routine gender-based violence (GBV) screening, counseling, and referrals in health care settings, including HIV care; however, considerable implementation barriers exist. This stud...

Real‐world outcomes of nivolumab‐ AVD and brentuximab vedotin‐ AVD in paediatric and adult advanced‐stage Hodgkin lymphoma

Summary Brentuximab vedotin (BV)‐doxorubicin, vinblastine and dacarbazine (AVD) and nivolumab (N)‐AVD have transformed the frontline treatment of advanced‐stage Hodgkin lymphoma (HL), yet real‐world comparative data remain limited. In this multicentre retrospective study across 1...

Assessing the role of plan complexity and target geometry through multi‐institutional gel based end‐to‐end QA in multi‐focal single isocenter stereotactic radiosurgery

BACKGROUND: Single-isocenter stereotactic radiosurgery enables efficient treatment of multiple brain metastases (SI-MBM SRS), but demands high geometric accuracy. Plan complexity metrics are increasingly used as indicators for quality assurance (QA) performance, however their app...

Associations of Brain Structure and Neuropsychological Function With Artificial Intelligence Estimates of Biological Vascular Age

BACKGROUND: Accelerated vascular aging, assessed as artificial intelligence–based vascular age (AIVA), is associated with small vessel disease that may impact brain structure and neuropsychological function. METHODS: In a cross-section of Framingham Heart Study participants, AIVA...

Pneumolysin Attenuates Lethal Streptococcus pneumoniae Superinfection Following SARS-CoV-2 Infection

Streptococcus pneumoniae (Spn) is a common bacterial co-infection in patients with respiratory viral infections, including influenza and SARS-CoV-2, and is associated with increased morbidity and mortality. However, the mechanisms underlying the severe disease caused by SARS-CoV-...

The Relationship Between Incarceration History and Dental Care and Oral Health in the United States: A Scoping Review

OBJECTIVES: To conduct a scoping review of observational quantitative studies examining the association between prior incarceration and (1) dental care use, (2) dental insurance coverage, and (3) oral health outcomes among US adults. METHODS: A search strategy was implemented acr...

Microbial Dysbiosis, Infection, and Immunometabolic Signaling in Polyendocrine Metabolic Ovarian Syndrome (Formerly PCOS)

Polyendocrine metabolic ovarian syndrome (PMOS), recently proposed as a new name for polycystic ovary syndrome (PCOS), is a heterogeneous endocrine–metabolic disorder characterized by hyperandrogenism, ovulatory dysfunction, and variable ovarian morphology. Low-grade inflammation...

Functional antibody responses and protection against symptomatic dengue

Exposure to dengue virus (DENV) triggers the development of anti-viral antibodies that may contribute to either protection or disease progression. Antibodies exist in different isotypes and subtypes, with diverse specificities and functions. IgG antibodies are produced during pri...

Landscape of approaches for streamlining pre-analytical and early analytical variables for solid tumor next-generation sequencing: A Genomics Organization for Academic Laboratories consortium report

The scope of pre-analytical and early analytical methods used in clinical molecular laboratories can have vast effects on the quality and turnaround time for solid tumor next-generation sequencing assays. To learn more about various approaches, a survey of 24 academic laboratorie...

Arthroscopic Bankart Repair With Hill‐Sachs Remplissage Shows Low Recurrence and Excellent Outcomes for Primary and Revision Surgery at Midterm Follow‐Up

Purpose To assess midterm outcomes, including recurrence and patient‐reported measures, after arthroscopic Bankart repair with remplissage in both primary and revision cases. Methods A retrospective, single‐surgeon review was performed on patients who underwent arthroscopic Banka...

Plasma Aβ42/Aβ40 predicts longitudinal amyloid pathology and clinical progression in amyloid-PET negative individuals with subjective cognitive decline

Early detection of amyloid-β (Aβ) pathology is critical for timely intervention in Alzheimer’s disease (AD). Changes in plasma Aβ42/Aβ40 levels appear early in the AD continuum, but whether they precede amyloid deposition detected by Aβ-PET requires further research. Data from 16...

Nutritional optimization for older adults undergoing hip fracture surgery: a randomized controlled pilot trial

Objectives: To identify the incidence of malnutrition in elderly patients with hip fracture, evaluate the impact of a nutritional intervention, and assess feasibility of study design. Design: Randomized controlled pilot trial. Setting: Level 1 trauma center. Patients/Participants...