Institution
The University of Texas at San Antonio Health Science Center
Recent research
- BiologyOpen access
Structural variants (SV), genomic alterations spanning more than 50 base pairs, can significantly impact gene expression and protein function. However, their contribution to Alzheimer’s disease (AD) remains poorly understood. Leveraging a novel SV calling pipeline, we identified...
- Health & MedicineOpen access
Towards Automating Junctional Hemorrhage Control Using AI for Interpretation of Human Tissue
Junctional hemorrhage has a high fatality rate due to how difficult it is to control rapid bleeding from major vessels. The available methods to stop junctional blood loss are prone to placement errors as well as failure during transport and during prolonged field care. On the ba...
- BiologyOpen access
Non-enzymatic hepatic ABHD6 interacts with Akt-FoxO1 axis to regulate metabolic health
The enzymatic role of ABHD6 in insulin secretion and resistance is well documented. However, its non-enzymatic function, especially its effects on metabolic health, including selective hepatic insulin resistance and metabolic dysfunction-associated steatotic liver disease (MASLD)...
- Health & MedicineOpen access
Bile acids (BAs) play critical roles in regulating glucose, lipid and energy metabolism, but its effects on type 2 diabetes is not very clear, we studied the effects of ursodeoxycholic acid (UDCA) intervention on blood glucose and related metabolic indexes in type 2 diabetes rats...