The University of Melbourne

Progress, challenges, and future directions of pancreatic cancer surveillance in high-risk populations

Pancreatic cancer remains one of the most lethal malignancies because most patients are diagnosed with advanced disease, when curative treatment is rarely possible. Population-wide screening is not currently recommended because pancreatic cancer remains relatively uncommon. Early...

Developmental Care and Follow‐Up of Infants Exposed to Alcohol and/or Drugs in Utero: An Australian Benchmarking Survey

AIM: Infants exposed to alcohol and/or drugs (AoD) in utero are at considerable risk for developmental complications which are amenable to early intervention. There are no published guidelines in Australia for the allied health care of infants and toddlers (0-2 years) who have be...

Stochasticity in response to rostrocaudal and mediolateral determinants influences inaccurate specification within kidney organoids

The differentiation of human pluripotent stem cells to kidney requires the accurate recapitulation of complex morphogenetic patterning events within an in vitro environment. Current protocols are assumed to accurately pattern through intermediate mesoderm to kidney with outcomes...

Mild malformation of cortical development with oligodendroglial hyperplasia in epilepsy (MOGHE): genetics, mechanisms and precision therapy

Mild malformation of cortical development with oligodendroglial hyperplasia in epilepsy (MOGHE) is a recently defined malformation of cortical development that is an important cause of childhood-onset drug-resistant epilepsy. Clinically, the epilepsies associated with MOGHE are h...

Inspiration or instigation? Bidirectional links between body-focused content, body image, and disordered eating urges

Using ecological momentary assessment (EMA), we examined the bidirectional relationship between body-focused inspiration content and body image and disordered eating urges, as well as the potential moderating effect of gender on these relationships. Undergraduate men and women (n...

Resistant starch as a dietary strategy for metabolic and gut health: Implications for Asia-Pacific populations.

BACKGROUND AND OBJECTIVES: Metabolic diseases are rising rapidly across the Asia-Pacific region as traditional diets are displaced by refined, low-fibre foods. Resistant starch (RS) is a fermentable dietary component that modulates gut microbial activity and short-chain fatty aci...

When the map is not the territory: a duoethnographic inquiry into language portraits, ideology, and researcher reflexivity

Language portraits are now a routine tool in multilingual identity research. Their conventions have been examined critically within the field, yet the flatter version that circulates in many applied uses has received less of the scrutiny applied to other research instruments. In...

Building the toolkit to address malaria resurgence and radical cure of vivax malaria in Ethiopia: a meeting report

Abstract Ethiopia has experienced a substantial resurgence in malaria in recent years, with increasing case numbers and a growing contribution of Plasmodium vivax in several regions. At the same time, new evidence supporting improved radical cure strategies, including high-dose p...