Sungkyunkwan University

Integrative Genomic Analysis Reveals Molecular and Clinical Disparities between Bladder and Upper Tract Urothelial Carcinoma in K-MASTER Program

Purpose: The clinical outcome of urothelial carcinoma presents significant variability, reflecting its molecular composition, epidemiologic attributes, and primary site of origin. Despite histological similarities, upper tract urothelial carcinoma (UTUC) and bladder urothelial ca...

Living alone, socioeconomic status, and mortality among older adults: a population-based cohort study

This study examined the association between living alone, socioeconomic status, and mortality among community-dwelling older adults. We analyzed mortality outcomes among 3,771 participants aged ≥ 60 years enrolled in the Korean Longitudinal Study of Aging (KLoSA) beginning in 200...

Maternal diabetes and childhood cancer risks in offspring: a nationwide cohort study

Maternal diabetes is associated with several adverse childhood outcomes, but its link to childhood cancer remains inconclusive. We investigated this in a nationwide birth cohort using the Korean National Health Insurance database. We analyzed women who delivered singletons betwee...

KiGEP: a quantitative algorithm for calculating human kidney similarity and nephrotoxicity in human kidney organoids

Kidney organoids (KOs) are being actively developed and used as models for evaluating nephrotoxicity, which is an important process during drug development. To evaluate human pluripotent stem cell-derived KOs, various lineage markers have been used to confirm KO differentiation v...

Effect of armed conflict on measles surveillance and zero-dose vaccination status in Tigray, Ethiopia, 2018–2024

Abstract Background Armed conflict disrupts health systems, undermining routine immunization and disease surveillance. These disruptions can delay outbreak detection and allow population susceptibility to accumulate unnoticed. This study assessed the impact of the 2020–2022 confl...

Association between stride length variability and osteosarcopenia in community-dwelling older women: a cross-sectional study

Abstract Background Osteosarcopenia, the coexistence of sarcopenia and low bone mass, raises the risk of falls, fractures, and functional decline, yet its diagnosis depends on dual-energy X-ray absorptiometry (DXA) and muscle function testing, which are difficult to apply routine...