Sungkyunkwan University

Risk Factors for Stereoacuity Impairment in Intermittent Exotropia: Results from a Nationwide Korean Study

Purpose: To identify clinical factors associated with stereoacuity impairment in patients with intermittent exotropia (IXT), with an emphasis on perinatal, refractive, motor, and sensory parameters. Methods: This nationwide cross-sectional study analyzed 5,385 Korean patients wit...

Early On-Treatment Host Fitness Dynamics Refine Prognostic Stratification in Advanced NSCLC Receiving First-Line Immunotherapy

PurposeWe assessed whether baseline and early on-treatment measurements of host fitness using the Prognostic Nutritional Index (PNI) provide complementary prognostic information in advanced non-small cell lung cancer (NSCLC). Materials and MethodsWithin the prospective, multicent...

Nostalgia as an affective driver in running: Associations with intrinsic motivation, serious leisure, flow, and well-being

This study tested an integrated model to examine how nostalgia for running experiences functions as an affective driver promoting intrinsic motivation, serious leisure, flow, and well-being among young adult runners. Cultural differences were explored in these relationships by co...

Closed‐Loop Solid‐State Synthesis Planning for Materials Discovery With Large Language Models

Developing reliable synthesis routes for complex materials remains a major bottleneck in accelerating materials discovery. This study establishes a large language model-based framework for predicting and optimizing synthesis conditions directly from the literature data. Key synth...

Harnessing Li‐Ion Binding Energy for Solvation‐Guided Electrolyte Additive Design and Robust Solid Electrolyte Interphase Reinforcement

The rational design of electrolyte systems is essential for stabilizing the electrode-electrolyte interface to enhance the electrochemical performance of lithium-ion batteries (LIBs). Although conventional strategies focus on the introduction of specific functional moieties, the...

Prenatal PM2.5 exposure drives epigenetic reprogramming of fetal macrophages linked to atopic dermatitis

Abstract Prenatal environmental exposures are increasingly recognized as contributors to atopic dermatitis (AD), yet the underlying mechanisms remain unclear. Fine particulate matter (PM 2.5 ), a complex mixture of airborne pollutants, has been associated with elevated risk of al...

Diffusion-weighted chemical exchange saturation transfer MRI in the human brain at 7T

Metabolite diffusion provides information on unique intracellular environments that are not captured by water diffusion. Conventional diffusion-weighted magnetic resonance spectroscopy (DW-MRS) is a useful tool for probing metabolite diffusion, but lacks spatial information. In t...

Geographic Access to Care and Mortality in Cardiogenic Shock: A Nationwide Cohort Analysis

IMPORTANCE: Timely access to advanced care is critical for patients with cardiogenic shock (CS), yet the impact of regional disparities in hospital arrival time on mortality remains unclear. OBJECTIVES: To investigate whether regional disparities in hospital arrival time are asso...

Alginate-Based Ternary Composites for Water Treatment: Synthesis, Mechanisms, and Applications

Alginate, as a natural polymer, has been widely used in the removal of pollutants in water due to its renewability, biocompatibility and abundant functional groups. However, it still has some limitations such as low specific surface area, poor mechanical strength and single funct...

Machine learning force field molecular dynamics simulation of SEI formation on lithium metal

Abstract Lithium metal batteries represent a cornerstone technology for next-generation energy storage systems owing to their exceptional energy density. However, the extreme reactivity of lithium metal drives continuous parasitic reactions with electrolytes, causing interfacial...

Sulfur‐Free Ultrahigh‐Refractive‐Index Polymers Enabled by Densely Packed Oxygen‐Bridged Dibenzofuran‐Cardo Architectures

ABSTRACT Sulfur‐free polymeric materials simultaneously achieving ultrahigh refractive index ( n > 1.8), low optical dispersion, high visible transparency, and thermal robustness have remained elusive due to the fundamental polarizability–dispersion trade‐off. Here, we introdu...

Electronic‐Geometric Pre‐Compensation Enables Intermetallic RhSb Bimetallenes for Efficient Nitrite Electroreduction

ABSTRACT Sustainable electrochemical synthesis aims to produce high‐value chemicals under mild conditions, but its advancement is hindered by electrocatalyst deactivation caused by the strong adsorption of poisoning intermediates. Strategies that mitigate deactivation by weakenin...

A structured framework for standardizing lifestyle data: core data interoperability (CDI) model with expert validation

Lifestyle factors, such as smoking, alcohol consumption, and physical activity, are among the most critical modifiable risk factors for morbidity and mortality; however, their representation in health data remains inconsistent and unstructured. Although electronic medical record...

RAF1 extrachromosomal DNA amplification confers acquired erlotinib resistance in a non-small cell lung cancer cell model

EGFR (epidermal growth factor receptor)-targeted therapies, which utilize small molecule inhibitors such as erlotinib and osimertinib to inhibit aberrantly activated EGF receptors caused by oncogenic mutations such as L858R and exon 19 deletion occurring primarily in the region c...

Defect-mediated generation–recombination dynamics governing conductance response in floating-body transistors

As CMOS technologies evolve toward ultra-thin floating-body architectures, defect-mediated carrier dynamics increasingly dominate device behavior, challenging conventional linear interpretations of electrical response in nanoscale transistors. In this work, we demonstrate that th...

Synergistic Integration of SrFeO 3 Nanoparticles With Exfoliated MXene (Ti 3 C 2 T x /V 2 CT x ) Nanosheets for High Performance Supercapacitors

ABSTRACT The performance of supercapacitors is often limited by conventional electrode materials, which typically necessitate a compromise between energy density, power density, and cycling stability. While two‐dimensional MXenes offer high conductivity and surface area, their pr...

Retinal disease classification from spectral domain optical coherence tomography using lesion attentive fusion

Retinal diseases such as central serous chorioretinopathy (CSC) and neovascular age-related macular degeneration (nAMD) can cause permanent vision loss, and their diagnosis from three-dimensional spectral-domain optical coherence tomography (SD-OCT) volumes is challenging because...

Optimizationof the Composition of NiFe-PBA Nanomaterialsand Synergistic Enhancement of Electrochemiluminescence from GoldNanoclusters via Pleated Ce-MOF: A New Strategy for S100B Immunoassay

Abstract As a blood biomarker associated with cerebral infarction (CI), the ultrasensitive detection of S100 calcium-binding protein B (S100B) is of great significance for the early warning of CI. Electrochemiluminescence (ECL) technology holds tremendous application potential du...

Phenotyping Sepsis at Emergency Department Presentation Using Early Clinical Data: A Multicenter Cohort Study

Background: Sepsis is heterogeneous, and early emergency department (ED) management is constrained by limited information and dynamic clinical trajectories. Methods: Using the nationwide Korean Sepsis Alliance (KSA) registry, we applied k-means clustering to nine routine ED varia...

Regional brain morphometric correlates of CT-defined metabolic dysfunction-associated steatotic liver disease and hepatic fat burden

Hepatic steatosis is the defining imaging feature of metabolic dysfunction-associated steatotic liver disease (MASLD) and is detected on abdominal CT. Whether CT-defined MASLD and hepatic fat burden are associated with brain morphometric variation beyond cardiometabolic and CT-de...