RWTH Aachen University

Modified bauxite residue blended cements – The effects of Na- and Al-rich pozzolans on phase assemblage and pore solution composition

Several thermochemical treatments were developed to transform bauxite residues (BR) into reactive SCMs: co-calcination, vitrification and reductive smelting. This study investigates the impact of these treatments by comparing activated BR blended cements (10 to 50 wt.% SCM) obtai...

Cross-sectional relationships between memory scores and neurodegeneration biomarkers in patients with suspected cognitive impairment

INTRODUCTION: We aimed to examine whether additional metrics derived from the CERAD Word List Memory Test (WLMT) such as acquisition patterns, error frequencies, and consolidation efficiency, are associated with cerebrospinal fluid (CSF) biomarkers of amyloid and tau pathology, a...

Simplification and the level of protection—primary law limits and legislative discretion in the Food and Feed Safety Omnibus

Abstract Background On 16 December 2025, under the label “Simplification Omnibus”, the European Commission tabled a legislative proposal (COM (2025) 1030 final) that simultaneously amends various legal acts in the area of food and pesticide law. As regards plant protection produc...

Integration of proteomic aging clocks in a phase 2a clinical trial supports simultaneous geroprotective assessment

Abstract Drugs for aging-related diseases may modulate aging itself, but standard clinical trial designs cannot detect such effects. Aging clocks could close this gap, but epigenetic models often yield inconsistent, hard-to-interpret results. In contrast, proteomic clocks, by tra...

NFDI4ING Fiona Summer School "Driving RDM": 0. Cover

NFDI4ING is the National Research Data Infrastructure for the Engineering Sciences. To educate Research Data Management (RDM), NFDI4ING's archetype Fiona conducts a summer school as practice-oriented training. Following the slogan "Driving RDM", a small-scale data-driven engineer...

In-situ synthesis of gold nanoparticles within a self-assembled multiblock copolymer matrix for electrospun hybrid nanofibers

Abstract Nanostructured materials (NMs) are a key subject in contemporary technological advancements due to their unique optical, electrical, and catalytic properties. Thus, this work investigates the fabrication and functionalization of nanofibers obtained from polystyrene- bloc...

Climate-responsive robotic brickwork for monolithic building envelopes

Abstract This research aims to reconcile geometric complexity and environmental performance in robotic bricklaying by proposing an integrated design-to-fabrication methodology for site-specific, monolithic building envelopes. As a sustainable alternative to contemporary multi-lay...

Machine learning is good for physics—and vice versa

Abstract Scientific AI is rapidly transforming fundamental physics research and challenging defining aspects of the fundamental physics methodology. We discuss opportunities and dangers of this transformation and find exciting benefits from a close interaction between AI and fund...

Cononsolvency‐Assisted Fabrication of Hydrogels and Microgels With Tunable Porosity, Diffusivity and Stiffness

ABSTRACT Porous materials including hydrogels offer high potential for applications requiring controlled mass transport, cell infiltration, and mechanical properties, such as tissue engineering, drug delivery, or soft robotics. We report a facile method for the synthesis of hydro...

Signals of Communicative Intent Enhance the Impact of Emotional Messages from Human Speakers, While Effects for Robots are Attenuated

Abstract The present work investigated humans’ responses to robots’ verbal emotional expressions. To this end, the interplay of agent characteristics and signals of communicative intent on emotional word processing was examined. In two behavioral studies (N1 = 36, N2 = 72), parti...

Well-Posedness of the Linear Regularized 13-Moment Equations Using Tensor-Valued Korn Inequalities

Abstract. In this paper, we finally prove the well-posedness of the linearized R13 moment model, which describes, e.g., rarefied gas flows. As an extension of the classical fluid equations, moment models are robust and have been frequently used, yet they are challenging to analyz...

Volumetric and functional connectivity alterations of the thalamus and thalamic nuclei groups in drug-resistant focal epilepsy: A 7T MRI study

Abstract Purpose Through its global and extensive connections with multiple brain structures, the thalamus can play an important role in seizure propagation. This study investigated volumetric and functional connectivity alterations of the thalamus and more specifically the thala...

Periodic reassessment or permanent approval? A critical analysis of the EU Commission’s proposal to reform pesticide and biocide authorisation in Europe

Abstract On 16 December 2025, the European Commission published proposal COM(2025) 1030 within the Food and Feed Safety Simplification Omnibus, aiming to amend Regulation (EC) No 1107/2009 on plant protection products and Regulation (EU) No 528/2012 on biocidal products. The prop...

Material and grinding behavior analysis of cemented carbides with cobalt-reduced and cobalt-free binder materials

Abstract Manufacturing companies require large numbers of high-performance cutting tools, which are often made from cemented carbides due to their high hardness and toughness. Cobalt (Co) is typically used as a binder because of its favorable mechanical properties and the high so...

Operational Degradation of Flooded Lead–Acid Storage Under Frequency Containment Reserve: Long-Term Evidence from a Hybrid Multi-Technology BESS

Flooded lead–acid batteries continue to operate in utility-scale battery energy storage systems (BESSs), yet their long-term degradation under grid-frequency regulation remains poorly characterized by field evidence. This paper presents an eight-year, multi-indicator degradation...

Cullin 3 ubiquitin ligase regulates redox defense and metabolic programs in proximal tubule cells

Abstract Background Chronic kidney disease (CKD) is characterized by proximal tubule (PT) stress, oxidative injury, and metabolic dysfunction. Human kidney single-nucleus RNA-sequencing (snRNA-seq) identified enrichment of ubiquitin-dependent protein catabolic processes in injure...

Dystonia 3×3: A Training Guideline for Beginners in Botulinum Neurotoxin Treatment of Cervical Dystonia

Cervical dystonia (CD) is a hyperkinetic movement disorder characterized by involuntary muscle contractions leading to abnormal postures of the head and neck. The injection of botulinum neurotoxin type A (BoNT-A) into the muscles involved is the treatment of choice for CD. BoNT-A...

Integrative Muscle-Adipose Score (IMAS)

OBJECTIVE: To investigate the potential of integrating muscle and fat compartments into a novel and unified score for outcome prediction in a bicentric European cohort of LT recipients. BACKGROUND: Body composition (BC) reflects nutritional status and metabolic reserves and influ...

Weakening Local Chemical Bonds for Enhanced Thermoelectric Performance in YbMg 2 Sb 2 Zintl Compounds

ABSTRACT Alloying is a well‐established strategy for reducing lattice thermal conductivity ( κ L ) and enhancing thermoelectric performance of materials, typically explained by the Klemens model, which describes the point‐defect phonon scattering via mass and size contrasts. Yet,...

The Global Epidemiology of Metabolic Dysfunction-Associated Steatotic Liver Disease: Regional Hotspots, Trends, and Future Projections

Purpose of Review This review highlights the global prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD), assesses comparability of the former definition of non-alcoholic fatty liver disease (NAFLD)-era estimates with the 2023 steatotic liver disease (SL...