RWTH Aachen University

Zincblende-/Diamond-Structure Nanocrystals: Analytic Surface Energies by Size, Shape, and Surface Orientation

Abstract Recently, the universal analytics for the intrinsic shape of zincblende (zb) and diamond-lattice nanocrystals (NCs) were described [AIP Adv. 6, 085306 (2016)], determining exact numbers for their internal atoms NNC, internal bonds Nbnd, and interface bonds NIF as a funct...

Harmonization, interoperability and an open architecture for all the stakeholders of a pan-European electrical system: the vision of the project OneNet

This work offers an overview of the essential findings of the project OneNet, which aims to enable a pan-European electrical system where the heterogeneous landscape of stakeholders, markets and platforms across Europe can openly participate at all levels. The paper outlines the...

Understanding spatial and temporal evolution of progressive excavation damage zone in granitic rocks – development of a novel mine-by and laboratory experimental framework at the BedrettoLab

Abstract. The brittle damage around tunnels in the form of spalling is common in massive crystalline rocks subjected to high in-situ stresses. Understanding the short-term development and long-term evolution of the Excavation Damage Zone (EDZ) is particularly important for deep g...

Active hazardous slow faults drive drainage evolution in the Atacama Desert

This is a preprint of manuscript soon to be sumbitted to a peer-review journal. The Atacama Desert of the Central Andean forearc is the driest non-polar region on Earth, where extremely low erosion rates preserve geomorphic markers over Myr timescales. Between 19°S and 20°S, subt...

Construction of personal health knowledge graphs for clinical data harmonization in breast cancer

Integrating heterogeneous personal health data and maintaining clinical registries for breast cancer management is labor-intensive. This study presents an AI-powered virtual assistant transforming identifiable breast cancer patient data into interoperable personal health knowledg...

Bounty Hunter: Autonomous, Comprehensive Emulation of Multi-Faceted Adversaries

Adversary emulation is an essential procedure for cybersecurity assessments such as evaluating an organization’s security posture or facilitating structured training and research in dedicated environments. To allow for systematic and time-efficient assessments, several approaches...

Identifying aspects of social sustainability in the context of digitalised production: a scoping review

While numerous studies investigate the social impacts of digital technologies in production, the literature lacks a comprehensive and explicit identification of the aspects constituting social sustainability in this context. As these impacts are context-dependent and vary across...

Integration of Polymer Optical Fibers in Nonwoven Geotextiles for Continuous Strain Monitoring

Geotextiles are often used in large scale civil engineering projects, such as dams and embankments. Failure of these structures can lead to significant economic losses as well as mortal danger. Still, current monitoring solutions of such structures often rely on discontinuous, ex...

$$\phi $$-Extropy in Discrete and Continuous Settings

Abstract The concept of $$\phi $$ ϕ -extropy is introduced as a generalization of extropy for discrete random variables, in analogy with Khinchin’s $$\phi $$ ϕ -entropy. The $$\phi $$ ϕ -extropy framework replaces the logarithmic function in the classical (Shannon) extropy defini...

Neuromonitoring of perioperative microembolization and its association with postoperative stroke after carotid endarterectomy

Abstract Purpose This study aims to assess whether perioperative microembolization can identify patients at risk for postoperative stroke. Methods A total of 257 carotid endarterectomy procedures in 254 patients were analyzed (154 symptomatic, 103 asymptomatic). Neuromonitoring,...

Nanofinishing of wool and blended fabrics with TiO 2 for UV protection and photoyellowing reduction

The effectiveness of nanocrystalline titanium dioxide (TiO 2 ) (P-25) in enhancing protection against ultraviolet rays and reducing photoinduced yellowing was evaluated through its application to wool fabrics and wool blends (such as wool–polyester and wool–polyester–spandex). Th...

One‐Step Access to Ultra‐Bright Macrocyclic Oligo‐BODIPYs Featuring Long‐Lived Cyclic Excitons

ABSTRACT The controlled organization of chromophores into defined assemblies with collective photophysical properties is a key concept for natural and artificial photonic systems. A template‐free, one‐step synthesis affords a series of methylene‐bridged macrocyclic oligo‐BODIPYs...

FIND: a phase-II study to evaluate the efficacy and safety of erdafitinib in FGFR-altered NSCLC

Abstract Introduction: FGFR alterations occur in approximately 2% of non-small cell lung cancer (NSCLC) patients, predominantly in squamous cell histology (sqNSCLC). We evaluated the efficacy of the selective FGFR1-4 inhibitor erdafitinib in patients with FGFR-altered NSCLC. Meth...

A Finite‐Strain Phase‐Field‐Regularized Elastoplastic Damage Model for Polypropylene

ABSTRACT A rotation‐free finite‐strain phase‐field‐regularized elastoplastic damage formulation is presented for the tensile failure simulation of polypropylene (PP). The bulk response is represented by a hyperelastic–isotropic–plastic material branch formulated in a corotated in...

New potassium binders: we need them - we do not need them

Abstract New potassium binders may facilitate contemporary chronic kidney disease care by controlling hyperkalemia and thereby facilitating the continued use of kidney- and cardioprotective therapies, particularly renin-angiotensin-aldosterone system inhibitors. The opposing view...

Intraoperative ventilation settings in Germany: an observational multicentre cross-sectional study

Intraoperative lung protective ventilation and, in inhalational anesthesia, minimal fresh gas flow (FGF) are recommended. It remains unclear how these recommendations are transferred to clinical routine. We aimed to assess corresponding anesthesia practices in Germany and raise a...

Pre-ECMO characteristics, organ dysfunction and exploratory mortality prediction in COVID-19 versus non-COVID-19 ARDS treated with veno-venous ECMO: a retrospective cohort study

Abstract Objective The transferability of pre-ECMO characteristics and established mortality prediction tools across COVID-19 (C-19) and non-COVID-19 (nC-19) acute respiratory distress syndrome (ARDS) remains uncertain. We compared clinical characteristics, organ dysfunction, res...

Flexibility of the TRMT10C N-Terminal Domain Helix Explored by Molecular Dynamics Simulations

Abstract The human mitochondrial tRNA methyltransferase TRMT10C contains a 41-residue long positively charged α-helix in its N-terminal domain, interacting with tRNAs from the anticodon to the T-loops. Here, we investigated the flexibility of this N-terminal long α-helix using co...

Asymptotic-Preserving Schemes for the Initial-Boundary Value Problem of Hyperbolic Relaxation Systems

Abstract. In this work, we present a numerical method for the initial-boundary value problem (IBVP) of first-order hyperbolic systems with source terms. The scheme directly solves the relaxation system using a relatively coarse mesh and captures the equilibrium behavior quite wel...

Adaptive Catalytic Synthesis of Aromatic and Aliphatic Amines via CO2-Induced Feedback Inhibition Using Standard Hydrogenation Catalysts

Abstract Adaptive catalytic systems, able to adjust or be adjusted reversibly in their performance, are finding increasing interest in science and technology. Yet, their development is currently associated with sophisticated catalyst designs integrating catalytic and stimuli-resp...