National and Kapodistrian University of Athens

Web application for retrospective geomagnetic storm detection, main phase analysis and identification of solar wind influence on storm intensity

This work presents a web application for retrospective detection and analysis of geomagnetic storms using hourly Dst and solar wind data from OMNIWeb. The application detects storm events, identifies their main phases, computes solar wind derived parameters during the main phase,...

Classification of Seasonal Allergic Rhinitis Patients by Prospective Patient‐Recorded Symptoms: The @ IT .2020 Project

BACKGROUND: Seasonal allergic rhinitis (SAR) has been so far classified according to frequency and severity by retrospective information based on the ARIA (Allergic Rhinitis and its Impact on Asthma) classification. Electronic symptom diaries (e-Diaries) are feasible tools to col...

Oral health and systemic health outcomes: A call for interdisciplinary action

Abstract Objectives To make the case, from periodontology and dental public health, for interdisciplinary action on oral and systemic health, and to set out recommendations for practice, policy, education, and research. Materials and Methods A joint working group of the European...

Proteolytic enzymes chymotrypsin and papain combined with Alexandrite laser hair removal versus laser hair removal alone for the treatment of facial hirsutism: a randomized comparative study

Laser hair removal is the treatment of choice for reducing unwanted hair in hirsute patients. However, preventing hair regrowth remains a challenge. This study aimed to evaluate the combined effect of laser and enzymatic hair removal. Fifty-nine Greek women with facial hirsutism...

Metal‐Free Decarboxylative Allylation of N‐Protected Amino Acids and Carboxylic Acids via Thioxanthone Photocatalysis

ABSTRACT In response to the growing demand for efficient synthetic methodologies, we report herein a practical and cost‐effective photochemical decarboxylative allylation protocol, utilizing thioxanthone as an affordable organic photocatalyst under blue‐LED irradiation. This meta...

Explainable Optimized Machine Learning for Predicting Student Self-Regulated Learning

This study examined the utility of an optimized, explainable machine learning (ML) model for predicting students’ self-regulated learning (SRL). Participants were 823 middle school students (52.6% girls) from randomly selected public schools who completed in-person measures of re...

Milvexian with Antiplatelet Therapy after Acute Coronary Syndrome Event

BackgroundPatients are at increased risk for recurrent ischemic events after an acute coronary syndrome event. Milvexian, an oral factor XIa inhibitor, may reduce the risk of major adverse clinical events with minimal bleeding risk. MethodsIn this phase 3, randomized, placebo-con...

The efficient star-forming regions of stripped-envelope supernovae

Abstract Massive stars ($\ge 8\, \rm {M}_{\odot }$) play a key role in shaping the interstellar medium of galaxies through stellar feedback. However, how these stars form and evolve before exploding as core-collapse supernovae (SNe) remains elusive. We compute for the first time...

Severity of Reactions in Double-Blind Placebo-Controlled Food Challenges: New Insights From the EuroPrevall Outpatient Clinic Study

BACKGROUND AND OBJECTIVES: Oral food challenge, particularly double-blind placebo-controlled food challenge (DBPCFC), is the gold standard for diagnosis of food allergy, although safety concerns limit its widespread use. Objectives: To evaluate the severity of reactions during DB...

Translation, Cultural Adaptation, and Evaluation of the Psychometric Properties of the Greek Version of the Rapid Weight Loss Questionnaire for Combat Sports Athletes

Rapid weight loss (RWL) is commonly practiced among combat sports athletes to reduce body mass before competition. The Rapid Weight Loss Questionnaire (RWLQ) is a self-report instrument designed to assess weight loss behaviors and practices. This study aimed to translate and cult...

Integrating Instagram into anatomy and histology education: A comprehensive review of current evidence and pedagogical outcomes

Purpose Instagram is a highly popular social media platform, which has been implemented as a teaching modality of several disciplines. We performed a literature review of its use for anatomy and histology teaching, given the lack of reviews with this purpose. Methods We searched...

Verification Index for the Repositioning of a Single Implant Analog in the Correct Place: A Clinical Technical Case Report

Background and Clinical Significance: Implant impressions can present inaccuracies, affected by many factors, such as impression technique, impression material, and parallelism or lack thereof among the implants. The use of a verification index can assess the accuracy of the mast...

Targeting SUV4–20H2-mediated H4K20 methylation restrains growth and migration in pediatric high-grade astrocytomas

Pediatric astrocytomas are characterized by increased molecular and clinical heterogeneity with epigenetic alterations contributing to aggressiveness and therapy resistance. The repressive histone mark H4K20 trimethylation (H4K20me3) and the methyltransferase SUV4–20H2 (KMT5C) ar...

Histological manifestations of vitamin A toxicity in the liver

Vitamin A (VitA) is a fat-soluble micronutrient involved in various physiological processes. Its sustained intake exceeding physiological needs leads to increased hepatic accumulation warranting careful monitoring for potential health implications. Despite being widely studied in...

Impact of Response to Hypomethylating Agent‐Based Therapy on Survival Outcomes in the Context of Baseline Clinical‐Molecular Risk and Transplant Status in Patients With Higher‐Risk Myelodysplastic Syndromes/Neoplasms: An analysis From the International Consortium for MDS (icMDS)

Baseline IPSS-M risk, response to hypomethylating agent (HMA) therapy, and receipt of allogeneic stem cell transplant (allo-HCT) have all been individually shown to impact overall survival (OS) in patients with myelodysplastic syndromes (MDS). However, the prognostic impact of re...

Myeloma Elderly Prognostic Score ( MEPS ): A Proposed Prognostic Score Integrating Age, Renal Function, Performance Status, and Ultra‐High‐Risk Cytogenetics

Established disease-centered prognostic systems may be less tailored to elderly/non-transplant-eligible (NTE) patients with multiple myeloma (MM), in whom host-related factors such as age, performance status, and renal function strongly influence all-cause outcomes. We developed...

Effects of SMILE on intraocular pressure and corneal biomechanics: a systematic review and meta-analysis

Abstract Purpose Small incision lenticule extraction (SMILE) is a popular flapless refractive procedure for myopia and myopic astigmatism, although postoperative corneal biomechanical changes may affect intraocular pressure measurements and glaucoma assessment. This systematic re...

Proteomic Profiling reveals that DPP4 overexpression increases Cell Adhesion, inhibits cell migration, And Restores Androgen Sensitivity in Prostate Cancer

Dipeptidyl peptidase-4 (DPP4), a serine protease with both enzymatic and non-enzymatic roles, has emerged as a context-dependent modulator of tumor progression. In this study, we investigated the expression and function of DPP4 in androgen-sensitive and androgen-resistant prostat...

Adjuvanted Leishmania infantum extracellular vesicles induce protective immunity in experimental visceral leishmaniasis

Abstract The lack of an effective vaccine remains a critical barrier to controlling visceral leishmaniasis (VL), a lethal parasitic disease with expanding global incidence. Here, we evaluate extracellular vesicles (EVs) released by stationary-phase Leishmania infantum promastigot...

Primary Biliary Neuroendocrine Tumors: A Systematic Review of Surgical Management, Oncologic Outcomes and Implications for Personalized Care

Background/Objectives: Primary biliary neuroendocrine tumors (PBilNETs) are exceptionally rare biliary tract neoplasms that are frequently misdiagnosed preoperatively as cholangiocarcinoma because of overlapping clinical and radiological findings. This systematic review aimed to...