Nanjing University

Photo‐Generated 1 O 2 Triggers In Situ RNA Crosslinking for High‐Contrast Tumor MRI and Effective Tumor Suppression

ABSTRACT High‐contrast imaging and effective treatment of hepatocellular carcinoma (HCC) remain challenging, largely due to the limited tumor selectivity of existing contrast agents and the absence of stable and broadly conserved therapeutic targets. Herein, we report a photoacti...

Orientation-tunable correlated Chern insulating states in chiral twisted double bilayer graphene proximitized by WSe2

Moiré flat bands in graphene systems proximitized by transition-metal dichalcogenides (TMDCs) provide a setting where spin-orbit coupling (SOC) can reshape band topology. The crystallographic alignment angle Φ between TMDC and graphene layers is predicted to tune the balance of I...

Bidirectional Multi‐Channel Programmable Metasurface for High‐Security Wireless Information Steganography

ABSTRACT With inherent abilities of directly modulating digital information on reflection and transmission properties, programmable metasurfaces have been extensively explored in wireless communications. However, realizing multi‐channel metasurface‐based wireless communication th...

Selective Recovery of Lithium from Spent LiFePO4 Cathode Powder Using the [BSO3HMIm]HSO4–H2O2 System

Abstract The recycling of spent LiFePO4 cathodes is critical for meeting the growing demand for lithium and reducing dependence on primary mining. Conventional hydrometallurgical routes are typically limited by high reagent consumption, poor selectivity, and secondary pollution,...

Association of transglutaminase-2 with contrast-induced acute kidney injury in Chinese patients with acute coronary syndrome: a prospective cohort study

BACKGROUND: To investigate the dynamic changes in serum and urinary Transglutaminase-2 (TG2) levels in acute coronary syndrome (ACS) patients and their association with contrast-induced acute kidney injury (CI-AKI), thereby providing novel clinical evidence for risk prediction of...

Revisiting the productide (Productidina, Strophalosiidina) brachiopod fauna from upper Visean (Mississippian) reefs in Belgium and UK: systematics, palaeoecology and evolutionary implications

The Asbian (upper Visean, Mississippian) reefs of North Yorkshire, Derbyshire (UK) and Visé (Belgium) host rich brachiopod faunas studied since the 19th century. This paper revises the productide brachiopods, which dominate the benthic assemblages in both abundance and diversity....

“Good Me” and “Bad Me” Function in the Relationship Between Child Neglect and Adolescents’ Social Networking Addiction

This two-wave longitudinal research aims to investigate the temporal relationship of child neglect on adolescents’ social networking addiction through the mediating mechanism of inferiority and the moderating effect of self-compassion and left-behind status. A total of 629 Chines...

Genetic links between IIIE iron meteorites and the core of the HED parent asteroid

Rocky planets formed through the differentiation of planetesimals into metal‑rich cores and silicate mantles, yet direct evidence linking these complementary reservoirs remains scarce. Here we show that IIIE irons and howardite-eucrite-diogenite (HED) meteorites are genetically l...

Controlled flight of high-thrust ultralight ion-propelled microrobot with integrated sensing

Ion wind technology holds potential for the miniaturization of flying microrobots, generating thrust without mechanical moving parts, enabling simplified and light designs free from high-frequency actuators. Nevertheless, two fundamental challenges have limited its practical impl...

Intranasal Delivery of Gallium–Quercetin Nanoparticles for Multi‐Target Ferroptosis Inhibition in Parkinson's Disease

ABSTRACT Ferroptosis contributes to Parkinson's disease (PD) through interconnected processes including iron dysregulation, oxidative stress, and mitochondrial dysfunction, yet current therapies targeting single pathways remain insufficient. Herein, we developed gallium–quercetin...

MBNL1 hijacks a structured single-stranded distal DNA element to sustain FLT3 expression in KMT2A-rearranged leukemias

The molecular mechanisms by which KMT2A-rearranged (KMT2A-r) leukemias maintain the oncogenic FLT3 expression remain largely unclear, limiting therapeutic opportunities. Here, we identify the RNA binding protein MBNL1 as an unexpected positive regulator of FLT3 by DepMap dataset...

Distinct Yet Coordinated: Pattern of Leaf and Root Fungal Endophyte Communities in an Alpine Meadow

Leaf and root fungal endophytes (LFEs and RFEs) represent essential yet distinct components of the plant holobiont, but their ecological relationships remain poorly understood. Here, we investigated the community structure of LFE and RFE across 45 plant species in an alpine meado...

Exploring non-linear influences of urban environment on urban vitality using multi-source geographic big data

Urban vitality (UV) is a crucial indicator of the prosperity, livability, and sustainability of cities, yet its complex and non-linear relationship with the urban environment (UE) remains underexplored. Therefore, taking Nanjing as the study area, this study integrated multi-sour...

Geosynthetic reinforcement and drainage in fine-grained embankments under rainfall

The increasing use of locally sourced fine-grained soils in embankment construction increases susceptibility to rainfall-induced instability due to low permeability, high water retention and limited shear strength. This study investigates the coupled reinforcement–drainage behavi...

Modifying Surfactants Within Divergent Pores of Cluster‐Based Metal‐Organic Frameworks for Syngas Electrosynthesis

ABSTRACT The electrochemical reduction of CO 2 to syngas (CO and H 2 ) provides a potential pathway for synthesizing fuels, but the ability to modulate the syngas composition across a wide range using a catalyst of invariant composition faces considerable difficulties. Herein, we...

Assessing EFL Learners’ Phraseological Competence Through Association Measures: The Role of Reference Corpus Selection

ABSTRACT Association measures, such as pointwise mutual information (PMI), have been widely used to explore learners’ phraseological competence. Yet, the validity of PMI‐based evaluations critically depends on the reference corpus employed, and the extent to which this methodolog...

Refined Multi-Source Satellite and Reanalysis Diagnostics Reveal Topographic Anchoring and Thermodynamic Control of the Tibetan Plateau Ozone Valley

The Tibetan Plateau ozone valley is a prominent summertime ozone minimum in the Northern Hemisphere upper troposphere–lower stratosphere (UTLS), with implications for regional radiative balance and climate. Although previous studies emphasized large-scale circulation during the A...

Phage as a prospective arsenal against superbugs

The escalating crisis of antimicrobial resistance (AMR) necessitates the urgent development of alternatives to traditional antibiotics. Bacteriophage (phage) therapy, which utilizes viruses that specifically infect and lyse bacteria, has re-emerged as a promising therapeutic stra...

Apoptosis of Mdm2-deficient osteocytes enhances osteogenesis through TRPM8-enriched apoptotic vesicles

During homeostasis, osteocyte apoptosis is typically associated with bone loss through enhanced osteoclast recruitment and bone resorption. However, whether apoptotic osteocytes also regulate bone formation remains elusive. Here we report that conditional deletion of Mdm2, an E3...

Understanding and Detecting Android R8 Compiler Bugs

Android apps currently dominate the smartphone app market, and their reliability will significantly affect user experience and even induce security risks. Since Android Gradle Plugin 3.4.0 (April 2019), the R8 compiler serves as the default infrastructure in the Android build pro...