Nanjing University

Calcium-Associated Cellular Integrity and MAPK/cAMP Signaling Are Associated with Low-Temperature Acclimation in Schizophyllum commune 20R-7-F01

Temperature is a critical environmental factor affecting fungal growth, morphogenesis, and reproduction. Schizophyllum commune, a model basidiomycete fungus, exhibits remarkable developmental plasticity under environmental fluctuations; however, the mechanisms underlying its adap...

Role of desolvation on biomolecular liquid–liquid phase separation

Abstract Biomolecular condensates play essential roles in cellular organization and are implicated in diverse pathological processes. Their formation is driven by liquid-liquid phase separation (LLPS), a process that requires coordinated multistep desolvation of biomolecular chai...

Employee Creativity in Project-Based Organizations: Inhibited or Promoted by Organizational Controls?

Creativity and control are both vital to creative project-based organizations: The former enables innovation, adaptability, and problem-solving in uncertain or novel conditions, whereas the latter ensures alignment, stability, and goal-directed execution within constraints. Never...

Gate-tunable large second-order and third-order nonlinear Hall effect in topological insulator BiSbTeSe 2

The nonlinear Hall effect (NLHE) holds significant promise for next-generation electronic device applications, and it is essential to explore and engineer a strong and highly tunable NLHE. In this work, we report large second-order and third-order NLHEs in dual-gated BiSbTeSe2 de...

Evaluation of the Global Fibrinolytic Capacity of Whole Blood

Abstract Assessment of the global fibrinolytic capacity of whole blood is of great clinical value for the diagnosis of bleeding and thrombotic disorders, the guidance of therapeutic decision-making, and prognosis monitoring. However, due to the complexity of the fibrinolytic syst...

Local Correlation-Based Machine Learning Enables Coupled-Cluster-Level Energetics for Thousand-Atom Molecular Systems

Abstract Data-intensive molecular workflows increasingly require consistent energies for many molecules and configurations. High-accuracy data are much scarcer because the small energy differences governing conformational preferences and molecular recognition can require an accur...

Improved estimation of net ecosystem CO 2 exchange over North America using LSTM-based flux upscaling (2001–2021)

Accurate estimation of regional-scale terrestrial carbon budgets is of great importance but remains challenging. With particular advantages, the Long Short-Term Memory (LSTM) network method shows potential for improving regional carbon budget upscaling estimations. Here, using LS...

Cross-Channel effects of online reputation and offline event participation in B2B Platforms: Synergy or Attenuation?

This study examines how online reputation and offline event participation jointly relate to seller performance on B2B platforms. Although omnichannel research often predicts online–offline synergy, the interaction between these channels remains underexplored in B2B platform setti...

A nuclear clock synchronized to 229Th

Abstract Atomic clocks have made time and frequency the most precisely measured quantities in physics, progressing from microwave standards that realize the SI second 1 to optical clocks with unprecedented precision 2 . A nuclear clock transfers the frequency reference from an el...

Predicting regional gray swans via translocation: AI weather models and Dubai’s unprecedented 2024 rainfall

Artificial intelligence (AI) models have transformed weather forecasting, but their skill for unprecedented weather extremes is unclear. Here, we analyze GraphCast, AIFS, and FuXi forecasts of the unprecedented 2024 Dubai storm, which had twice the training set’s highest rainfall...

Bony labyrinth taxonomic identification and long-term evolution of livestock in the Southwest and Central Asia

Abstract Southwest and Central Asia were pivotal regions for the domestication and dispersal of domestic herbivores. Here we investigate long-term variation in bony labyrinth morphology of domestic bovids (sheep, goats and cattle) across the last 10 000 years. We focused on the o...

MOF-mediated cascade photoreactions under nanoconfinement for defluorination of per- and polyfluoroalkyl substances

Heterogeneous catalytic degradation of per- and polyfluoroalkyl substances (PFAS) through cleavage of the strong C-F bonds offers a robust and sustainable approach for mitigating their global threat to ecosystems and human health. However, current reduction or oxidation methods g...

Symmetry-engineered and electrically tunable in-plane anomalous Hall effect in oxide heterostructures

The anomalous Hall effect has long served as a cornerstone for uncovering low-dissipation quantum phenomena and powering Hall-based functionalities, yet its tunability and device application are constrained by the orthogonal relationship among electric field, Hall current, and ou...

Research on deep learning-based missing echo restoration method for weather radar mosaic data

Radar mosaic data represent a critical and widely utilized resource in weather forecasting. Nevertheless, the frequent occurrence of regional radar echo gaps, caused by factors including radar hardware malfunctions, data delivery delays, and software processing errors – each cont...

The total serum N-glycome landscape of hematological malignancies

A holistic and dynamic view of the glycomic landscape in hematological malignancies (HMs) remains poorly characterized, hindering clinical the application of glycomics in HMs. We launched a large-scale analysis of multicenter cohorts, combining retrospective (n=1,370) and prospec...

Preclinical Evaluation of 68Ga-Labeled Heterodimers for Dual Integrin αvβ3 and PARP1-Targeted Tumor Imaging

Abstract Tumor heterogeneity limits the diagnostic performance of molecular imaging probes targeting a single biomarker. Here, we report the design, synthesis, and preclinical evaluation of 68Ga-labelled heterodimeric radiotracers co-targeting integrin αvβ3 and poly(ADP-ribose) p...

Distinct Dependencies of Tropical Cyclone Inner‐Core and Outer‐Region Precipitation on Translation Speed and Intensity

Abstract This study analyzes how tropical cyclone (TC) precipitation in the inner core (IC) and outer region (OR) varies with translation speed and storm intensity using satellite‐derived precipitation data. Inner core precipitation initially increases with translation speed but...

Ultrasensitive Electrochemiluminescence Aptasensor With DNA Nanotetrahedron Amplification for Multilevel Detection of cTnI From Cells to Patients

ABSTRACT Accurate detection of myocardial injury (MI) biomarkers for assessing anticancer drug‐induced cardiotoxicity has long been constrained by insufficient capture efficiency and limited assay sensitivity. To address this challenge, we developed an electrochemiluminescence (E...

Characteristics and Ambient Conditions of Mesoscale Convective Systems Moving Offshore in the Yangtze‐Huai River Basin, East China

Abstract This work for the first time studies the characteristics and environment conditions of mesoscale convective systems (MCSs) that move offshore (i.e., land to sea, LS) in the Yangtze‐Huai River Basin (YHRB), East China. In the warm season (April–September), LS MCSs account...

Consistent estimates of carbonyl sulfide and methane stratospheric lifetimes retrieved from AirCore profiles at different latitudes

Stratospheric loss is a major sink for both carbonyl sulfide (COS) and methane (CH 4 ), but their stratospheric lifetimes and sinks remain poorly constrained because high-resolution observations of their vertical distributions in the lower stratosphere are sparse. Here, we estima...