Nagoya University

Validation and refinement of a biomarker panel for frailty assessment and prediction of muscle weakness in older adults

Abstract Frailty is a complex geriatric syndrome characterized by age-related declines in physiological function and cognitive reserve. To promote early prevention and intervention, minimally invasive and objective biomarkers that can detect frailty progression are required. We a...

Development Process of Convective Cells in Coastal and Inland Areas Within a Snow Streak: a Case Study Using X-Band Polarimetric Radar in the Ishikari Plain, Japan During a Winter Monsoon Surge

Abstract Snow streaks associated with winter monsoon surges frequently produce coastal snowfall over the Ishikari Plain, Hokkaido. However, the processes responsible for inland precipitation containing graupel remain less well understood than those in coastal areas. This study in...

REAP1/AtSWAP70 integrates RAB5 and ROP signalling during sexual reproduction

Small GTPases of the Ras superfamily are critical regulators of diverse cellular processes. While crosstalk between their signalling pathways has been documented in animals, similar mechanisms remain unexplored in plants, where small GTPases have undergone unique evolutionary div...

Robotic 3-DoF rotation of oocytes driven by acoustic microstreaming

The rotational operation of oocytes plays a critical role in embryo engineering, particularly in assisted reproductive technology, cloning, and gene research. The conventional manual method relies heavily on operator experience and repetitive trial-and-error processes, while exis...

Late middle Pleistocene fossil coral reef growth history in the subtropical Northwest Pacific

Abstract During the Middle and Late Pleistocene, the Earth experienced rapid millennial-scale climate and sea-level fluctuations associated with 100 kyr-glacial-interglacial cycles. However, understanding of the timing and amplitude of these changes, and their impact on coral ree...

Employment Status, Self-Rated Health, and Stress Among Family Caregivers of Community-Dwelling Care Recipients in Japan

Background/Objectives: With population aging, increasing attention has been directed toward family caregivers balancing paid employment and caregiving responsibilities. This study aimed to investigate the association between employment status and self-rated health and stress amon...

Prognosis and risk factors by histologic type of malignant ovarian germ cell tumors in Japan: a JSOG gynecologic tumor registry-based study

Objective: This study evaluated prognosis and risk factors for overall survival (OS) in malignant ovarian germ cell tumors (MOGCTs) using data from the Japan Society of Obstetrics and Gynecology tumor registry.Methods: Data from 1,538 MOGCT patients (2004MOGCT patients ( -2019) )...

Building-level demolition and material output forecasting using 4d-GIS: a case study of Kitakyushu City, Japan

Abstract This study proposes a disaggregated modeling approach to estimate building-level demolition probabilities and project future material output. Many existing Material Stock and Flow Analysis (MSFA) studies rely on aggregated spatial units at national, prefectural, or munic...

Intramolecular Hydride Transfer Racemization Coupled with Enzymatic Kinetic Resolution Enables Asymmetric Syntheses of Caged Compounds

Abstract Caged molecules featuring the pentacycloundecane framework and related substructures represent an exciting class with numerous potential applications, yet reports of their asymmetric syntheses are scarce. In this work, we report a method for the asymmetric synthesis of t...

The equalities of interleaving distances and cohomology interleavings of spaces over $$BS^1$$

Abstract The cohomology interleaving distance (CohID) is defined and considered in the category of persistent differential graded modules over a field. As a consequence, we show that, in the category, the distance coincides with the homotopy commutative interleaving distance , th...

Left Bundle Branch Capture During Left Bundle Branch Area Pacing: A Diagnostic Accuracy Systematic Review

ABSTRACT Background Left bundle branch area pacing (LBBAP) does not necessarily achieve true left bundle branch (LBB) capture, and misclassifying left ventricular septal pacing (LVSP) as LBB capture may bias procedural decisions and outcome interpretation. We evaluated the diagno...

Do Readers Simulate the Color of Inferred Objects? Influence of Sentence Typicality and Context Position

Embodied cognition assumes that language processing involves sensory, motor, and affective representations. However, further empirical research is required to reveal how embodied representations are used in language processing. This study investigated whether readers could repres...

Demographic and clinical characteristics of rapidly progressive glomerulonephritis in renal vasculitis in the Japan renal biopsy registry

This study evaluated the clinical and demographic characteristics of biopsy-proven rapidly progressive glomerulonephritis (RPGN), with histological evidence of renal vasculitis. We focused on five vasculitis-related nephritides: MPO-ANCA, PR3-ANCA, anti-GBM, IgA vasculitis (IgAV)...

The parent bodies of Ryugu and Ivuna formed before those of other carbonaceous chondrites

Most carbonaceous chondrite (CC) meteorites contain abundant chondrules, millimeter-scale spherical inclusions of previously molten material. Ivuna-type carbonaceous chondrites (CIs) do not contain chondrules, nor do samples of the carbonaceous asteroid Ryugu. CIs and Ryugu share...

DeepLabCut-based automated system reveals diverse temperature tolerance among medaka strains and related Oryzias species

Abstract Temperature is a critical environmental factor influencing the physiology and behavior of ectothermic animals, yet conventional methods for evaluating thermal tolerance in fish rely on subjective manual observation of loss of equilibrium (LOE), limiting experimental thro...

The first four ground-level enhancements in the 1940s: investigation, digitization and analysis of forgotten data

Intense solar eruptions occasionally accelerate solar energetic particles (SEPs) and trigger ground-level enhancements (GLEs). Among the 77 known GLEs, the first four #1- 4, in the 1940s, took place before the advent of the standard neutron monitors (NMs) and were missing from th...

Reassessment of a cosmic ray increase event in 1279/1280 CE using carbon-14 records of tree rings.

Extreme solar energetic particle events (ESPEs) rarely occur on the Sun, as known from cosmogenic isotope proxies, the primary being 14C measured in tree rings. Several such events have been identified in tree-ring 14C data as sharp spikes. The most recent spike, around 1279 CE,...

Longitudinal hemifield-specific macular ganglion cell complex thinning and its association with arterial stiffness in eyes without baseline glaucomatous abnormalities

PURPOSE: To characterize longitudinal hemifield-specific changes in macular ganglion cell complex (GCC) thickness in eyes without baseline glaucomatous abnormalities and to evaluate whether arterial stiffness, assessed by brachial-ankle pulse wave velocity (baPWV), is associated...

Preferences and reasons for clothing colors in women patients and survivors of breast cancer in Korea

Purpose Clothing color can affect the psychological aspects in female patients and survivors of breast cancer; however, little is known regarding their preferences and reasons for choosing specific clothing color. This study aimed to explore the factors influencing their clothing...

Visualizing electron flow at transition states by natural reaction orbitals

Transition-state analysis in quantum chemistry provides structural and energetic information but does not directly reveal how electron density is redistributed at the onset of bond reorganization. Although frontier-orbital theory is highly effective for predicting reactivity from...