Nagoya University

A compilation of global bio-optical in situ data for ocean-colour satellite applications – version four

Abstract. A global in situ dataset for validation of satellite products from the ESA Ocean Colour Climate Change Initiative (OC-CCI) is presented. This version of the compilation, with data starting in 1996, extends to 2025, which is important for the validation of recent algorit...

Comparative Analysis of Ion and Electron Contributions to Ionospheric Ionization at Auroral and Subauroral Latitudes

Abstract Electron and proton precipitation into the nightside ionosphere is a key process in magnetosphere–ionosphere coupling. Although auroral electron precipitation at –10 keV is traditionally considered the main driver of auroral emissions, recent studies show that keV electr...

Microsatellite Instability‐High Somatic‐Type Malignancy Arising From a Primary Retroperitoneal Germ Cell Tumor: A Case Report

ABSTRACT Introduction Immune checkpoint inhibitors have shown only limited clinical efficacy in germ cell tumors (GCTs), underscoring the need for predictive biomarkers such as microsatellite instability‐high (MSI‐high). We report a rare case of mixed‐type GCTs treated with chemo...

Asymmetric defect distribution generates bulk Dzyaloshinskii–Moriya interaction in Pt/Co/Pt

The Dzyaloshinskii–Moriya interaction (DMI) in magnetic multilayers plays a pivotal role in spintronic applications by enabling the stabilization and manipulation of chiral spin textures, including chiral domain walls and skyrmions. While interfacial DMI in asymmetric multilayers...

Accurate AtomicDecomposition Method in 3D-RISM Theoryvia Multi-Input Linear Correction: Application to the Protein HydrophobicCore

Abstract Solvation free energy (SFE) is a fundamental thermodynamic quantity governing biomolecular processes in solution. Although the atomic decomposition method derived from the Kirkwood charging formula enables site-resolved evaluation of SFE contributions, its application wi...

Dynamic helical poly[4]helicene nanoribbon

<title>Abstract</title> The precise synthesis of helical graphene nanoribbons (GNRs) with a controlled handedness has a transformative potential as the promising chiral carbon materials. We now report the first synthesis of a dynamic helical poly[4]helicene nanoribbon, a novel cl...

Building a Physics-Aware AI Ecosystem for Solid-State Hydrogen Storage Materials

Abstract Hydrogen storage remains a central bottleneck for scalable hydrogen energy systems due to the multiscale and coupled nature of the thermodynamics, kinetics, and microstructural evolution of hydrogen storage materials (HSMs). Although artificial intelligence (AI) has acce...

Preoperative FIB ‐4 Index as a Potential Factor Associated With Severe Postoperative Complications and Endogenous Organ Failure After Hepatectomy for Hepatocellular Carcinoma

ABSTRACT Background Liver fibrosis influences tolerance to surgical stress, dictating postoperative complication risks after hepatectomy for hepatocellular carcinoma (HCC). While conventional systems assess hepatic function, they may not fully capture structural fibrosis. This st...

The Clinicopathological Characteristics and Prognosis of Cholangiolocarcinoma: A Multicenter Study With a Central Pathology Review

BACKGROUND: Cholangiolocarcinoma (CLC) is a rare liver cancer with ≥ 80% ductular configuration (DC). Given its rarity, its clinicopathological characteristics remain poorly understood, and its status as a distinct disease entity remains controversial. We conducted a nationwide m...

Experimental Development of Gaseous Propellant Mono-Cylindrical Rotating Detonation Engine Film Cooling

Thermal management remains one of the critical challenges in the advancement of rotating detonation engine (RDE) technology for practical propulsion applications. To facilitate progress in this field, this study investigates the use of gaseous film cooling via axial injectors, ai...

A Gradient-CorrectedPolarizable Continuum Model forImproved Reaction Fields at the SCF Level

Abstract We propose an improved model, termed the gradient-corrected PCM (GCPCM), for improving the energy accuracy of the polarizable continuum model (PCM). Our previous study revealed deficiencies of PCM in describing the reaction field, i.e., the electrostatic potential genera...

Fracture laterality as an independent prognostic factor for clinical outcomes after hip fracture surgery

Aims Fracture laterality is routinely recorded in large hip fracture registries for administrative purposes, yet rarely evaluated as a prognostic variable. We aimed to test whether laterality is independently associated with short-term outcomes after hip fracture surgery. Methods...

Evidence for latent regularities in echolocation-guided flight behaviour of bats

Abstract Echolocating bats navigate complex environments with remarkable agility, yet it remains unclear whether their flight trajectories are governed by reproducible internal policies shared within a species and across the controlled environments examined. To address this quest...

Day length may impose an ecological constraint on chick provisioning behaviour in a high-latitude seabird

Abstract Variation in daylight hours may shape light-dependent behaviours both across seasons and among latitudinally distinct breeding colonies. We investigated the influence of photoperiod variation on chick provisioning behaviour in a high-latitude seabird, the Manx shearwater...

Electrochemical Imaging of Hydrogen Evolution Reaction Sites at Transition Metal Dichalcogenide Nanosheets

Understanding spatial heterogeneity in catalytic activity is essential for designing efficient hydrogen evolution reaction (HER) catalysts. In this study, scanning electrochemical cell microscopy (SECCM) was employed to directly image local HER activity on transition metal dichal...

Exceptionally high thermoelectric power factors at low temperatures in heavily doped p- and n-type Ge-rich Ge1−xSnx films

Low-temperature thermoelectric thin films compatible with semiconductor technology are of increasing interest for cryogenic energy harvesting and thermal management of advanced Si-based electronics. Here, we show that heavily doped p- and n-type Ge1−xSnx epitaxial films exhibit e...

LRS1 phosphorylated in response to blue light regulates stomatal opening

Abstract Blue light receptor phototropin is a protein kinase that initiates various blue light signaling pathways, including the phosphorylation and activation of plasma membrane (PM) H + -ATPase for stomatal opening. Activation of PM H + -ATPase drives K + uptake via K + in chan...

Plasticity of extrachromosomal DNA segregation during drug adaptation

Uneven segregation during mitosis is a striking feature of extrachromosomal DNA (ecDNA). Because ecDNA lacks a centromere, it is thought to segregate stochastically, generating intratumoral heterogeneity in genomic copy number. Drug treatment can readily change ecDNA copy number,...

Total Synthesis of HemiketalD2 via a ConvergentCoupling Strategy

Abstract Hemiketal D2 (HKD2) is a recently identified eicosanoid produced from arachidonic acid via a crossover pathway involving 5-lipoxygenase (5-LOX) and cyclooxygenase-2 (COX-2), and has been shown to stimulate angiogenesis by inducing endothelial cell tubulogenesis. However,...

An N-terminal CDC42 T43I variant reveals the mechanism of pyrin inflammasome activation

Heterozygous carboxyl-terminal variants in the RHO guanosine triphosphatase (GTPase) CDC42 are known to cause severe autoinflammatory syndromes. Here, we identified a heterozygous amino-terminal p.T43I (Thr 43 →Ile) CDC42 variant in patients with autoinflammation and uncovered a...