Manipal Academy of Higher Education

Fetal atrial strain: a scoping review of physiology, methods, and clinical applications

Abstract Background The evaluation of fetal cardiac function is moving towards the angle-independent myocardial deformation techniques, including the atrial strain obtained with speckle-tracking echocardiography. Angle-independent myocardial deformation techniques are gaining inc...

Design and experimental validation of dual-feed cavity-backed slot antenna diplexer for millimeter-wave dual-band 5G applications

Abstract This article presents the development of a novel cavity-backed dual-feed miniaturized antenna with an intrinsic self-diplexing property for millimeter-wave dual-frequency 5G applications. The proposed device is designed using a rectangular substrate integrated cavity loa...

A comprehensive review of deepfake generation methods, detection strategies and open challenges in multimedia and Internet of Things systems

Abstract Deep Learning (DL) has driven extensive progress in Artificial Intelligence (AI) and data analysis in areas such as communication and computer vision but this progress also increased misuse. A significant example is deepfake technology, which produces highly realistic fa...

Bulk and single-cell multiomics insights into theca cell and granulosa cell dysfunction in polyendocrine metabolic ovarian syndrome

Abstract Polyendocrine metabolic ovarian syndrome (PMOS) is a heterogeneous disorder marked by a variety of clinical, hormonal, and metabolic disorders of an endocrine nature, affecting women of reproductive age and causing anovulatory infertility, metabolic dysfunction and hormo...

Translational design of multifunctional novasomes for theranostic-driven precision therapy of cutaneous oncology

Cutaneous oncology needs to be treated locally with maximal exposure to the target with minimum systemic toxicity. Novasomes, surfactant-rich vesicles, have proven to be promising theranostic carriers for both topical and intralesional delivery. This review aims to establish a tr...

Terminology for describing the 24-h cycle of physical activity, sedentary behaviour, and sleep: a scoping review

Abstract Background Physical activity, sedentary behaviour, and sleep are three behaviours which occupy the 24-h cycle and interact to influence a multitude of health outcomes. Different terms are currently used to describe these behaviours collectively (e.g., movement behaviours...

Successful caesarean section under spinal anaesthesia in a pregnant woman with guillain–barré syndrome: a case report from a resource-limited setting

Guillain-Barre syndrome (GBS) is a rare but serious neurological condition due to autonomic instability, decreased respiratory function, and unpredictable medication responses, which can make pregnancy difficult and provide considerable anaesthetic issues. We report a case of a 2...

A comparative evaluation of deep learning architectures, loss functions, and ensemble strategies for underwater fish species classification

Abstract The accurate classification of underwater fish species is important for biodiver-sity monitoring, sustainable fisheries management, and aquaculture. However, underwater fish classification remains challenging due to class imbalance, varying imaging conditions, and high v...

Association of small nerve fiber dysfunction on pain characteristics in type 2 diabetes mellitus individuals with chronic low back pain

Abstract Type 2 diabetes mellitus (T2DM) is associated with small nerve fiber (SNF) dysfunction. Quantitative assessment of thermal perception thresholds is a validated method for evaluating SNF dysfunction. Pain characteristics such as numbness and pain irritability are commonly...

Ears for examinations: a multicentre quasi-experimental evaluation of AI-generated revision podcasts on learning outcomes and retention among medical students

Abstract Background Medical curricula overload necessitates efficient, self-directed learning strategies that can utilize ‘dead time’ for study. AI-generated audio offers a scalable resource for this purpose, yet evidence regarding its efficacy in low-resource settings is limited...

Generalizations of Certain Summation Formulas Involving the Generalized Hypergeometric Function via Eslahchi and Masjed-Jamei

Classical summation theorems for generalized hypergeometric series constitute an important tool in the study of special functions. Motivated by earlier generalizations of these theorems, this paper derives several new summation formulas for generalized hypergeometric functions by...

Acute respiratory distress syndrome in scrub typhus: a systematic review and meta-analysis

PURPOSE: Acute respiratory distress syndrome (ARDS) is an important complication of scrub typhus and is associated with substantial mortality. The primary objective of this systematic review and meta-analysis was to estimate the proportion of hospitalised patients with microbiolo...

Effectiveness of Intra-Socket Application of Dexamethasone- and Hyaluronic Acid-Soaked Gelfoam in Mandibular Third Molar Surgery

Abstract Background Extraction of impacted mandibular third molars are commonly associated with postoperative pain, facial swelling, and trismus. Local intra-socket drug delivery provides targeted therapy with minimal systemic drug exposure. This study compared the efficacy of de...

Rebuilding green trust in the electric vehicle sector: a resilience theory perspective on post-greenwashing recovery strategies

Purpose The electric vehicle (EV) industry plays a pivotal role in global sustainability goals; however, its credibility has been undermined by greenwashing, misleading environmental claims that erode consumer trust. This study aims to examine how EV brands can restore trust afte...

TRAIL splice variant TRAILshort disrupts T cell receptor signaling and promotes immune tolerance in vivo

TRAIL is a TNF family ligand that trimerizes TRAIL-R1 (DR4) or TRAIL-R2 (DR5) to induce apoptosis, necroptosis, and/or NF-κB activation in receptor-bearing cells. We previously identified TRAILshort as a splice variant of TRAIL that lacks cysteine 230, cannot trimerize, and acts...

Corporate social responsibility and sustainable consumption behavior influencing consumer purchase intensions in FMCG sector

Abstract The excessive use and mismanagement of environmental resources have led to the rapid depletion of natural ecosystems, highlighting the urgent need for sustainable consumption practices. In response to increasing environmental concerns and global initiatives such as SDG 1...