Ludwig-Maximilians-Universität München

Ocularity modulates the dominance of spatial over temporal influences in binocular rivalry

The perception of a binocular rivalry (BR) stimulus can be influenced by other stimuli in temporal or spatial proximity. Here, we investigate how spatial (surround inhibition [SI]) and temporal context (flash suppression [FS]) interact. Previously, we modulated these influences b...

Pregnancy establishment in cattle without embryonic interferon tau

In ruminants, embryonic interferon tau (IFNT) is widely considered the indispensable signal for maternal recognition of pregnancy, driving endometrial gene expression to prevent luteolysis. However, this canonical paradigm has never been directly tested using genomic loss-of-func...

Low-Profile Versus Standard-Profile Endograft for Thoracoabdominal and Complex Abdominal Endovascular Aortic Treatment—Multicenter Cohort Study

Objective: The introduction of low-profile stent grafts (LPSGs) has proven to be a useful option despite initial concerns. The aim of this study was to analyze and compare the outcomes of standard-profile stent grafts (SPSGs) versus LPSG in a cohort of patients treated for thorac...

Outcomes of front-line tagraxofusp in patients with blastic plasmacytoid dendritic cell neoplasm (BPDCN) in a real-world scenario

Abstract Tagraxofusp (TAG), a CD123-directed protein-drug conjugate, is approved in front-line and relapsed/refractory blastic plasmacytoid dendritic cell neoplasm (BPDCN). Multicenter real-world outcomes and the contribution of up-front consolidation post-TAG remain less defined...

Serological and transcriptomic response of African fruit bats to immune challenge with recombinant vaccines expressing Ebola or Nipah virus antigens

Abstract Bats are hosts to diverse zoonotic viruses which can cause high case fatality rates in humans. Since detecting viruses in bats is difficult, antibodies are often used for surveillance, though their significance remains unclear in the absence of in vivo immunological stud...

Using multi-trait polygenic scores to predict lithium responsiveness in patients with bipolar disorder

Background The predictive power of polygenic scores (PGSs) for lithium treatment response in bipolar disorder remains limited. Aims To enhance the prediction of lithium responsiveness by developing a multi-trait PGS (mt-PGS) combining genetic information from multiple phenotypes...

Age-related bone mineral density patterns in a large German clinical DXA cohort: device-specific comparisons with international reference populations

In a large German clinical DXA cohort, comparisons with international reference populations were strongly device-dependent. iDXA values were consistently lower, whereas Prodigy Pro values showed closer but age- and cohort-dependent agreement. The data should not be interpreted as...

Diversity and distribution of ticks collected from vegetation and domestic animals in Zambia

Ticks are major vectors of pathogens affecting livestock and human health in sub-Saharan Africa, yet integrated data on tick diversity across ecological gradients remain limited. In Zambia, most studies have focused on livestock-associated ticks, with little emphasis on compariso...

Are childhood diseases associated with Molar-Incisor Hypomineralization? – Results from an observational study

Abstract Objective This observational study aimed to investigate the potential association between reported childhood diseases and medications during early infancy and the later appearance of molar incisor hypomineralization (MIH). Materials and methods As part of a prospectively...

Retrofitting language models to operate over bytes

Abstract Recent advances in artificial intelligence (AI) have largely been driven by large language models, deep neural networks that operate over discrete units called tokens. To represent text, most large language models use words or word fragments as the tokens, known as subwo...

Reference values and prediction equations for six-minute walk distance and stair-climbing test performance in apparently healthy Ethiopian adults

The six-minute walk test (6MWT) and stair-climbing test (SCT) are simple and practical measures of functional exercise capacity. Interpretation of performance requires appropriate population-specific reference values and prediction equations. However, reference data for apparentl...

Impact of on-site mobile CT imaging on prehospital patient management during the Munich Oktoberfest: a retrospective observational before–after study at a mass gathering

Abstract Background Mass gatherings such as the Munich Oktoberfest increase demand on Emergency Medical Services (EMS), particularly for trauma patients requiring imaging. Suspected mild traumatic brain injury (mTBI) often necessitates hospital referral and diagnostic imaging, pl...

Adoption of, attitudes towards, and perceived challenges of digital health in hospice and palliative care among professionals in Germany: a national cross-sectional web-based survey

Abstract Background Digital health technologies may support communication, symptom management, continuity of care, and access to services in hospice and palliative care. National data on their adoption, on professionals’ attitudes, and on perceived barriers are scarce. We examine...

Place and cause of death among people with chronic neurological diseases in Munich: a population-based study using death certificates

Abstract Introduction Access to palliative care is often delayed and fragmented for patients with chronic neurological diseases. This study aimed to characterize the place and cause of death among individuals with chronic neurological diseases to help identify potential gaps in p...

Movement synchrony in psychologically burdened parental couples during early childhood - A Motion Energy Analysis study in standardized conflict discussions

PREPRINT (NOT PEER-REVIEWED YET) Movement synchrony in psychologically burdened parental couples during early childhood - A Motion Energy Analysis study in standardized conflict discussions Anton K. G. Marx1*¶, Anamaria Semm1¶, Mitho Müller1, Lea T. Kaubisch1, Christian F. J. Wol...

Enumeration of Regular Multipartite Hypergraphs

Abstract. We determine the asymptotic number of regular multipartite hypergraphs, also known as multidimensional binary contingency tables, for all values of the parameters.

The tRNA‐Modification Geranyl‐2‐Thiouridine Enables RNA‐Lipid Association

The packaging of RNA in lipid nanoparticles for protection and delivery was key for the development of mRNA vaccines and therapeutics. Formulation requires the addition of a variety of lipids (including cationic) in high amounts to form complexes with the negatively charged RNA....

Junctional plakoglobin regulates intestinal epithelial cell proliferation via MAPK/ERK signaling

Junctional plakoglobin (JUP) is a desmosomal protein essential for epithelial tissue integrity and epithelial-immune cell crosstalk. Although JUP has been implicated in inflammatory processes, its role in intestinal epithelial repair remains unclear. In vitro, loss of JUP in Caco...

Real-time process analysis and optimization of nitroguanidine synthesis in microflow using inline Raman spectroscopy

Non-contact inline Raman spectroscopy is used as a fast, flexible, and safe method for monitoring and optimizing continuous-flow processes involving highly hazardous and corrosive materials. The synthesis of nitroguanidine (NQ), an energetic material, was characterized and optimi...

Selective Ultrafast Excitation and Dephasing of Gap Plasmons into Hot Carriers in Structural Color Generation

Abstract Plasmon-induced hot-carriers generated through Landau damping underpin applications in plasmonic optoelectronics, energy conversion, and photocatalysis. However, it remains unclear whether these carriers retain the spatial localization of their parent plasmon modes or ra...