Lanzhou University

Efficacy and Safety of DVDMS ‐Photodynamic Therapy for Dysphagia in Advanced Esophageal Cancer: A Phase II Clinical Trial

ABSTRACT Photodynamic therapy (PDT) is a localized treatment for esophageal stenosis and dysphagia in advanced cancer. This study evaluated the efficacy and safety of Cosiporfin sodium (DVDMS)‐mediated PDT for dysphagia in advanced esophageal cancer. In this Phase II trial, patie...

$$P_{c}(4312)$$, $$P_{c}(4440)$$, and $$P_{c}(4457)$$ productions in $$e^{+} e^{-}$$ collisions

Abstract In the present work, we propose to investigate the productions of $$P_{c}(4312)$$ P c ( 4312 ) , $$P_{c}(4440)$$ P c ( 4440 ) , and $$P_{c}(4457)$$ P c ( 4457 ) in the $$e^{+} e^{-} \rightarrow p \bar{p} J/\psi $$ e + e - → p p ¯ J / ψ process by utilizing an effective L...

Research advances in metal halides for flexible indirect X‐ray imaging

Abstract In recent years, metal halides (MHs) have emerged as ideal materials for indirect X‐ray detection scintillators due to their superior radiation luminescence properties, tunable luminescence, and low‐cost fabrication. However, rigid scintillators often suffer from dark co...

Beyond the Clock: Reprogramming Fertility in Diminished Ovarian Reserve

Diminished Ovarian Reserve (DOR) is a significant manifestation of female reproductive aging that profoundly impacts fertility and quality of life. In recent years, the emergence of aging reprogramming technologies has provided new insights into the mechanisms underlying DOR and...

Indole-3-propionic acid is an endogenic agonist of hypoxia-inducible factor-1α to protect the heart against hypoxia

Abstract Tryptophan catabolism by the gut microbiota is increasingly recognized as a hub connecting environmental challenges to cardiovascular health. By systematically profiling tryptophan metabolites in humans who had moved from low altitude to an altitude of 4300 m and in mice...

Planetary albedo change exacerbates surface warming: a perspective from cloud-type changes

Abstract. Persistent global warming is modulated by cloud changes, yet the specific contributions and associated controlling factors remain inadequately quantified. Using CERES radiation data with a surface energy-balance framework, we quantify the contribution of cloud radiative...

Functional niche partitioning influences species turnover across supraglacial microbial communities on the Longxiazai glacier, Tibetan Plateau

Glaciers represent unique ecosystems harboring diverse microbial communities that dominate biomass and drive biogeochemical cycling across supraglacial habitats. These microbes transform deposited modern and ancient carbon/nitrogen, and these elements are subsequently transferred...

Thinner roots were more efficient to increase soil organic carbon and benefited fungal necromass in an alpine meadow

Abstract Microbial necromass is a key regulator of soil organic carbon (SOC) stability in terrestrial ecosystems, and its formation is directly linked to microbial life cycles. Soil microbes are closely associated with plant community composition and the related root functional t...

A New Method of Solving the Time-Fractional Mixed Nonlinear Diffusion and Diffusion-Wave Equation

It is well known that meshless methods are effective for solving fractional differential equations on both regular and irregular domains. However, many commonly used basis functions such as Legendre wavelets and B-splines are naturally defined on rectangular domains, which limits...

Mixed Cropping Improves Soil Fertility via Enhancing Plant Facilitation in Alpine Artificial Grassland

By enhancing plant complementarity and facilitation, mixed cropping may accelerate soil fertility recovery and improve grassland ecosystem resilience. Nevertheless, the impacts of mixed cropping on soil fertility over a single growing season, and the underlying plant–soil interac...

Revisiting the critical role of stabilized Criegee intermediates (sCIs) in sulfuric acid formation: coupling mechanistic updates with interpretable machine learning

Abstract. Sulfuric acid (H2SO4) is a key driver of atmospheric new particle formation and subsequent growth, playing a critical role in the formation of sulfate aerosols. While stabilized Criegee intermediates (sCIs) are recognized to be one of the free radicals oxidated sulfur d...

Exploring baryon semileptonic decays through polarization and entanglement

Abstract The unitarity of the Cabibbo–Kobayashi–Maskawa (CKM) matrix is a cornerstone of the standard model (SM). Precise tests of this unitarity require independent determinations of its elements, such as | V us |, which governs the transition between strange and up quarks. Curr...

Elemental Cycling in Forest Soils

Soil is one of the most important natural resources on Earth; it is crucial for maintaining ecosystem stability and human survival [...]

Recent Advances in Caries Prevention and Non-Invasive Management: From Ecological Modulation to Precision Interventions

Background: Dental caries remains a globally prevalent biofilm-mediated disease driven by microbial dysbiosis and progressive enamel demineralization. The traditional “drill and fill” paradigm has increasingly given way to biologically informed preventive frameworks emphasizing e...

Simultaneous adjustment of accelerator alignment reference networks based on the classical stochastic model

Simultaneous adjustment is a critical technique for constructing high-precision accelerator alignment reference networks, which integrates measurements from multiple laser trackers. To address the specialized stochastic model used by the Unified Spatial Metrology Network (USMN) i...

Dataset Construction of CO2 Flux over Shifting Sand in the Taklimakan Desert and Assessment of Carbon Sequestration Capacity

Desert ecosystems, which cover extensive global regions, play an essential yet often-overlooked role in sequestering atmospheric CO 2 at substantial yet gradual rates, primarily due to insufficient monitoring, data scarcity, and limited research attention. Current assessments of...

Cyclic steepest descent is R-superlinearly convergent for almost every initialization on two-spectrum quadratics

We completely classify cyclic steepest descent (CSD) on strictly convex quadratics whose Hessian has exactly two distinct eigenvalues. At the beginning of each cycle CSD recomputes an exact steepest-descent stepsize and reuses it for m updates. For every m >= 2, write A = aP + bQ...

Cyclic steepest descent is R-superlinearly convergent for almost every initialization on two-spectrum quadratics

We completely classify cyclic steepest descent (CSD) on strictly convex quadratics whose Hessian has exactly two distinct eigenvalues. At the beginning of each cycle CSD recomputes an exact steepest-descent stepsize and reuses it for m updates. For every m >= 2, write A = aP + bQ...

Black hole entropy beyond the wald term in nonminimally coupled gravity: a covariant phase space decomposition

Abstract We study the entropy of static, spherically symmetric black holes in diffeomorphism-invariant theories with nonminimal matter–curvature couplings, using the covariant phase space formalism. For regular bifurcate Killing horizons, the Iyer–Wald construction gives the stan...

A counterexample to R-superlinear convergence of cyclic steepest descent

Cyclic steepest descent recomputes an exact steepest-descent stepsize once per cycle and reuses it for m updates. Dai's ICM 2022 survey states that this method is likely to converge R-superlinearly on n-dimensional convex quadratics when m is at least (n+1)/2. We show that the co...