King Saud University

Enhanced prediction of monthly reference evapotranspiration by optimizing SVR with the bagging algorithm in Indian Punjab

In this study, support vector regression (SVR) was enhanced with the Bagging (B-SVR) algorithm for monthly ET0 prediction at Ludhiana and Faridkot stations. The three different scenarios (S1, S2, and S3) were developed to predict monthly ET0 at study locations. The outcomes of th...

Metabolic Signatures Associated with COVID-19 Vaccination in Serum from Healthy Individuals

Background: COVID-19 vaccines have proven effective in reducing severe disease and mortality from SARS CoV-2 infection. The underlying molecular mechanisms and alterations in the human serum metabolome influencing the effectiveness and development of immunity remain unclear. Meth...

Oxygen-vacancy mediated charge dynamics in nano-engineered Ba/Co-doped MTiO₃ electron transport layers for enhanced organic solar cells

Engineering oxide electron-transport layers (ETLs) through defect and interfacial electronic-state control is an effective strategy for reducing charge-collection losses in inverted organic solar cells (OSCs). Herein, a hierarchical TiO₂/CoTiO₃ (CTO) bilayer ETL was developed by...

Innovative reinforced concrete-filled steel tube system: experimental and analytical flexural investigations

This study proposes an innovative reinforced concrete-filled steel tube (RCFST) system, wherein the steel tube is only extended over a limited span length. The flexural behavior of the proposed RCFST beams was experimentally investigated to consider two key design parameters — wi...

Gene flow, kinship, and source population assignment in Chrysomya blow flies

Abstract Blow flies of the genus Chrysomya are among the earliest colonizers of human remains and are important forensic indicators in Africa and the Middle East. However, the population genetic structure of Old World Chrysomya species in North Africa remains poorly understood. W...

Integrated experimental and computational exploration of 1,8-naphthyridine hydrazones as promising topoisomerase II-targeting anticancer agents

DNA topoisomerase II (Topo II) is essential for maintaining DNA topology during replication, transcription, and chromosome segregation. Its increased expression is associated with tumor progression, which makes it an appealing target for anticancer therapy. However, clinically us...

Medication reconciliation documentation and documented discrepancies in a tertiary Saudi hospital: a retrospective observational study

Abstract Introduction Medication reconciliation is a key patient-safety process during transitions of care, but its routine documentation and associated medication-list findings are not well described in Saudi tertiary hospital practice. This study aimed to characterize medicatio...

Sociodemographic factors and career growth as determinants of staff retention among nurses in a military hospital in Saudi Arabia

Nurses are the backbone of healthcare systems, and their retention remains a critical global challenge, as high attrition leads to a loss of expertise, continuity of care, and patient trust. The main objective of this study is to examine whether sociodemographic factors and caree...

Understanding the effect of various Chip breakers’ configurations and feed rates in high-speed drilling of Ti-6Al-4V alloy

Abstract High-speed machining (HSM) has emerged as a compelling paradigm in modern manufacturing industries owing to its potential to enhance productivity, improve surface integrity, and reduce overall machining time. However, the application of HSM remains limited primarily due...

Genome-Wide Analysis of Alternative Splicing Identifies a Prognostic Signature in ER-Positive Breast Cancer

Background/Objectives: Alternative splicing (AS) contributes substantially to transcriptomic diversity and has emerged as an important regulator of cancer progression. However, the genome-wide characterization of AS events specific to estrogen receptor (ER)-positive breast cancer...

Intranasal and Oral Pharmacological Sedation in Pediatric Dentistry: A Thematic Scoping Review of Efficacy, Recovery, and Safety Outcomes

Introduction: Conscious sedation (CS) is commonly recommended in pediatric dental clinics to manage uncooperative and anxious patients. Various routes of drug administration have been introduced to achieve effective CS. Among these, the intranasal (IN) route has gained popularity...

Perspectives of nursing among male pre-nursing students: a Q-methodology study

Nursing continues to face workforce shortages globally, and increasing the participation of men has been identified as one strategy for strengthening workforce capacity. In Saudi Arabia, efforts to expand and sustain the national nursing workforce have highlighted the importance...

Tomato leaf waste extract as corrosion inhibitor for copper–nickel alloy in H2SO4 medium

Abstract The tomato leaf waste extract (TLWE) was obtained through a decoction process and its effectiveness as a corrosion inhibitor on a copper–nickel alloy in sulfuric acid was assessed. Electrochemical measurements demonstrated that the extract functions as a mixed inhibition...

Evaluating ChatGPT’s Effectiveness for Arabic Dry Mouth Patient Education

Background/Objectives: The present study aimed to assess the understandability and actionability of Arabic text generated by a large language model for commonly searched Arabic queries on dry mouth. Methods: Using Google Trends, the top 10 searches worldwide related to ‘oral dryn...

Targeting Overweight and Obesity Phenotypes for Secondary Prevention of Cardiovascular Disease: A Call to Action for the Middle East and Beyond

ABSTRACT Although there are conflicting clinical data on the efficacy of weight reduction in reducing secondary events in patients with comorbid overweight and obesity (OAO) and cardiovascular disease (CVD), there is excellent epidemiological and biological evidence of a cause–ef...

Candidate epistatic mutation clusters in occult hepatitis B virus genotype D: a critical narrative review of the evidence gap and a proposed testable framework

Hepatitis B virus (HBV) genotype D is the dominant genotype across the Middle East. It forms the background against which diagnostic assays, blood-screening algorithms, and vaccination programmes operate in the region. Occult hepatitis B infection (OBI), the presence of replicati...

Fundamental Insights Toward Efficient Hydrogen Storage: Materials Design Considerations in Nanostructured and Polymer–Hybrid Systems

Hydrogen is a promising alternative energy source as the world moves toward decarbonization by reducing reliance on traditional fossil fuels. This review encompasses a comprehensive study of emerging materials for hydrogen storage, beginning with the physical and thermodynamic pr...

Single-photon double ionization of ozone: experiment and theory

Abstract The triatomic molecule ozone (O3) is of outmost physical and chemical importance in the atmospheres of our Earth and other planets. Beyond its environmental significance, a detailed understanding of the electronic structure and ionization dynamics of ozone is essential f...

Fine Tuning of Ag3PO4/g-C3N4 Hybrid Nanostructure Catalyst for Natural Sunlight-Assisted Cationic Dye Neutralization

Photocatalysis is a promising route for the environmentally friendly destruction of organic pollutants and recycling the polluted water in industrial contexts for future environmental challenges. In this novel research work, the coupling of definite proportions of silver phosphat...

Associations of screen time and physical activity with motor control, mood, and cognitive states in adolescents following acute high-intensity interval training

Excessive screen time and insufficient physical activity are increasingly common among adolescents and have been linked to adverse physical and psychological health outcomes. This school-based cross-sectional study examined associations between sedentary screen time, physical act...