King Saud University

Ordinary Steel–Copper Galvanic Cell for Peracetic Acid Activation: A Low-Cost Catalytic Oxidation Process for Sunset Yellow FCF

A commercial steel–copper galvanic cell is introduced, to the best of our knowledge for the first time, as a simple, self-driven, and low-cost platform for peracetic acid (PAA) activation and oxidative degradation of Sunset Yellow FCF (SSY) in water. This azo dye was used as a mo...

Progress in Anti-Obesity Drug Development: A Pharmacodynamics Perspective

Background/Objectives: Obesity is a chronic, multifactorial condition driven by complex neuroendocrine and metabolic pathways that limit the long-term success of lifestyle interventions. Pharmacotherapy has advanced from early monoaminergic agents to incretin-based and multi-rece...

Hydrochemical assessment and monitoring priorities in anthropogenically affected arid urban groundwater systems of Riyadh, Saudi Arabia

Study Region This study investigates arid urban groundwater in metropolitan Riyadh, Saudi Arabia, where limited recharge, intense evaporation, urbanization, agriculture, treated-wastewater reuse, industry, and landfills may alter carbonate and alluvial aquifers. Study Focus Forty...

In vitro and in vivo functional roles of three region 1 promoters in Escherichia coli K1 capsule gene cluster

Capsular polysaccharides are key virulence determinants in extraintestinal pathogenic Escherichia coli , protecting bacteria from host immune defences while modulating interactions with host tissues. In group 2 capsule gene clusters, transcription of region 1 genes required for c...

Hygiene and industrial safety education in Algeria: An assessment of university curriculum and student perceptions

Process safety education is essential for preparing engineers to manage risks in high-hazard industries. In Algeria, process safety competencies are primarily addressed through Industrial Hygiene and Safety (HSI) programs, although no dedicated process safety specialization curre...

From Infection to Oncology: AI-Assisted Drug Repurposing Uncovers Anti-Infective and Excipient-Class Compounds as PPAR-α-Linked Anticancer Agents

Drug repurposing offers an efficient strategy to identify novel anticancer agents from marketed compounds. We screened a library of ~1400 approved drugs using a PPARE–PPAR-α luciferase reporter assay to uncover modulators of lipid metabolism that induce cancer cell death without...

Clinical Factors Associated with Diagnostic Delay in Axial Spondyloarthritis in Saudi Arabia: A Retrospective Cohort Study

Background/Objectives: Diagnostic delay remains a major challenge in axial spondyloarthritis (axSpA), yet factors associated with delay in Saudi Arabia and the Arabian Gulf remain poorly characterized. We examined clinical factors associated with diagnostic delay in a single-cent...

Lash Ptosis and Entropion after Congenital Ptosis Surgery: Mechanisms and Treatment

PURPOSE: This perspective proposes a clinically useful framework for understanding upper eyelid lash ptosis and entropion after congenital ptosis surgery, linking potential mechanisms to prevention and management. METHODS: A focused literature review was performed. RESULTS: Posto...

Unlocking Latent Cycling Demand in Car-Dependent Riyadh, Saudi Arabia: A Weighted Multi-Perspective Planning Framework

Global transitions toward sustainable mobility often encounter structural and behavioural barriers in high-income, automobile-dependent metropolises. This study investigates the behavioural factors and planning preferences influencing bicycle infrastructure development in Riyadh,...

CT-based distribution of paranasal sinus involvement in sinusitis: A retrospective single-centre study

Background Sinusitis is among the most common inflammatory conditions of the paranasal sinuses, and computed tomography (CT) is the reference modality for demonstrating sinus involvement. The maxillary sinus is generally reported as the most frequently affected, but local data fr...

Compact target-aware stability-based feature selection for cross-dataset wearable activity monitoring

Wearable activity-recognition models may lose reliability when transferred across participants, sensor placements, sampling rates, acquisition protocols, and activity definitions. This study evaluates a compact unsupervised target-aware feature-selection strategy for cross-datase...

Identification of small defects in three-dimensional molded objects

The mold filling process can create small defects being trapped within the material, which compromise the strength of the cast piece. Here, we address the inverse problem of identifying the locations of these flaws using boundary measurements. To achieve this, we develop a numeri...

Transitional High-Al to Intermediate-Cr Podiform Chromitites from Wadi Zikt (Khor Fakkan Block, United Arab Emirates): Evidence for Reactive Melt Percolation during Nascent Forearc Evolution

Abstract Podiform chromitites at Wadi Zikt in the Khor Fakkan Block of the United Arab Emirates constitute a previously undescribed occurrence within the mantle section of the Semail ophiolite. We combine field relations, electron-probe microanalysis, in situ LA–ICP–MS mineral an...

Organic–Inorganic Dual‐Nanofiber Interpenetrating Network Scaffolds for Complementary Enhancement of Mechanical Stability and Osteogenic Bioactivity

ABSTRACT Incorporating nanofibers into 3D‐printed scaffolds is an effective strategy to enhance the physicochemical properties and osteogenic bioactivity of bone tissue engineering constructs. In this study, we developed a composite scaffold featuring a dual‐nanofiber interpenetr...

Towards Climate-Resilient Office Façades: Integrating PCM-Enhanced Glazing with Dynamic External Louvres Under Current and Future Hot–Arid Climates

Phase-change material (PCM) glazing and dynamic external shading are promoted as sustainable cooling measures, yet they act on the same solar load and are rarely assessed together under a mandatory energy code. This study aims to evaluate and compare the individual and combined p...

Dimer-interface effects on tetramer stabilization and tryptophan dynamics in allosterically modulated TPH-II

Tryptophan hydroxylase-II (TPH-II) controls the rate-limiting step of neuronal serotonin biosynthesis and plays a central role in neuropsychiatric health. As proper tetramer formation is essential for TPH-II stability and function, targeting its quaternary structure through allos...

Dose Optimization of Cefazolin for Pediatric Patients with Renal Impairment Using Physiologically Based Pharmacokinetic Modeling (PBPK) in GastroPlus

Background/Objectives: Cefazolin is a first-generation cephalosporin antibiotic widely used for the treatment and prophylaxis of bacterial infections in both adult and pediatric populations. It is predominantly eliminated unchanged by the kidneys. Impaired renal function can redu...

Exploring maternal sociocultural beliefs and practices in postpartum and infant care: perspectives of mothers and healthcare providers

Culture shapes beliefs and practices around infant care, affecting maternal and infant wellbeing during the postpartum period. This study explored mothers’ perceptions and beliefs about postpartum and newborn care in Saudi Arabia to identify misconceptions and inform strategies t...

First-principles investigation of hydrogen storage in pristine AlN nanosheets with a biphenylene framework

Abstract One of the most important aspects of the energy transition towards sustainable development is the efficient storage of hydrogen, for which a diverse range of materials is being studied. Here, we investigated the structural and electronic characteristics of biphenylene al...

Regulating the Local Coordination of Cd‐Glutamate Through Ligand Chirality for Efficient Alkaline Hydrogen Evolution

ABSTRACT The rational regulation of local coordination environments in metal‐organic complexes provides an effective strategy for tuning electrocatalytic activity; however, the influence of ligand chirality on hydrogen evolution remains largely unexplored. Herein, we report a ser...