Jilin University

Developing an explainable machine-learning model for short-term identification of neonatal cholestasis in preterm infants: a retrospective matched case-control study

Neonatal cholestasis (NC) is an important hepatobiliary complication in preterm infants, but its short-term identification before the first clinical diagnosis remains challenging. We aimed to develop an explainable machine-learning model for short-term identification of NC using...

Parametric design method for a hydrodynamic torque converter and its hydrodynamic-cavitation characteristics analysis

As a fluid transmission device, the hydrodynamic torque converter (HTC) achieves flexible transmission through energy conversion between impeller cascades and fluid. High-speed, high-power operating conditions and highly twisted cascade systems lead to highly developed three-dime...

Enhanced Performance and Stability of Paper‐Based Cs 3 Cu 2 I 5 Photodetectors via PVK In Situ Encapsulation

ABSTRACT The quest for resilient photodetectors in flexible electronics is met with the challenge of perovskite instability under mechanical stress and environmental conditions. This study introduces a Cs 3 Cu 2 I 5 /poly(N‐vinylcarbazole) (PVK) photodetector on paper, where PVK...

A Charge Supplement Strategy Enhanced Non-contact Triboelectric Sensor for In Situ Blade Lift Monitoring of Unmanned Aerial Vehicles

Real-time monitoring of blade lift is critical for the flight stability and safety of unmanned aerial vehicles (UAVs); however, conventional electronic speed controller estimation methods exhibit limited accuracy, high hardware costs, and susceptibility to signal drift. To addres...

Alliance orientation and radical innovation of new ventures in emerging economies: The role of organizational agility and digital technology adoption

New ventures in emerging economies often face substantial challenges in pursuing radical innovation, particularly under conditions of resource scarcity and environmental volatility. Integrating dynamic capability theory with the capability hierarchy perspective, this study examin...

Efficacy and Safety of Recibokibart, an Interleukin-36 Receptor Antibody, in Generalized Pustular Psoriasis: A Phase 2 Randomized Trial

BACKGROUND: Generalized pustular psoriasis (GPP) is a rare, severe inflammatory skin disease characterized by acute flares. Recibokibart is a humanized IgG1 monoclonal antibody targeting the interleukin-36 (IL-36) receptor. In a phase 1b open-label study, a single intravenous dos...

Waveform-preserving source-independent wave-equation-based local-scale traveltime inversion: Application to the SEG Chevron 2014 blind test dataset

Summary Full Waveform Inversion (FWI) leverages the amplitude and phase of full wavefield seismic data to obtain high-resolution subsurface structures by minimizing an objective function. However, FWI encounters severe cycle-skipping issues when the seismic data lack low-frequenc...

Neoadjuvant Anbenitamab and HB1801 in ERBB2 -Positive Breast Cancer

IMPORTANCE The combination of neoadjuvant taxanes with trastuzumab and pertuzumab remains the cornerstone treatment strategy in ERBB2 -positive breast cancer. Anbenitamab (a ERBB2 -biparatopic antibody that induces profound receptor clustering) and HB1801 (a solvent-free albumin-...

Exploring baryon semileptonic decays through polarization and entanglement

Abstract The unitarity of the Cabibbo–Kobayashi–Maskawa (CKM) matrix is a cornerstone of the standard model (SM). Precise tests of this unitarity require independent determinations of its elements, such as | V us |, which governs the transition between strange and up quarks. Curr...

A Hybrid CNN-Transformer Network for Linear Noise Suppression in 3D Seismic Data

Abstract 3D seismic data acquisition, processing, and analysis have become increasingly prevalent in modern geophysical exploration. However, various types of coherent noise, especially linear noise, can cause serious interference and effective noise reduction techniques are crit...

Palmitic Acid Inhibits the Proliferation and Hypertrophy of Antler Chondrocytes by Disrupting Mitochondria-Associated Endoplasmic Reticulum Membrane Function

As the only mammalian appendage capable of complete regeneration, deer antlers serve as an invaluable model to investigate cartilage regrowth, but the underlying mechanism remains unclear. This study revealed that addition of palmitic acid (PA), an abundant long-chain saturated f...

Enhanced Ultraviolet Circularly Polarized Light Detection through Tuning Constitutional Isomers in Chiral Benzo[ ghi ]perylenetriimides

ABSTRACT Chiral perylene diimides (PDIs) are promising candidates for circularly polarized light (CPL) detection due to their intrinsic chirality, outstanding photothermal stability and tunable molecular structures. However, the photocurrent dissymmetry factor ( g ph ) of CPL pho...

Controlling the Dynamic Conversion Process of the Water Molecules on the Electrolyte Interface for Producing Free Water

ABSTRACT Proton exchange membrane water electrolysis (PEMWE) is a highly promising green hydrogen production method and technology, and it is also one of the important means for scientists and engineers to achieve carbon reduction, carbon emission, and carbon neutrality. Years of...

Metabolic profiling reveals spatially-distinct reprogramming of host central carbon metabolism during Trichinella spiralis infection

The metabolic interplay between Trichinella spiralis (Ts) and its host remains a critical but underexplored aspect of trichinosis pathogenesis. Understanding how the parasite manipulates host metabolism is key to developing new diagnostic and therapeutic strategies. We employed t...

Mechanobiology of orofacial tissues: principles, mechanisms, and therapeutic applications

The orofacial system is constantly subjected to complex and dynamic mechanical forces and exhibits highly specialized mechanosensory and mechanoresponsive behaviors. However, current studies are mostly limited to single tissues or specific pathway analyses, which are insufficient...

Prescribed-Time Adaptive Robust Force Control of a Pump-Controlled Active Suspension Actuator for Rapid Pressure Build-Up

To address insufficient effective flow, delayed force response, and degraded tracking accuracy of pump-controlled active hydraulic suspension actuators during rapid pressure build-up and frequent reversal, a prescribed-time adaptive robust force control method based on a fixed-ti...

A phase III clinical trial of PXT3003 in Chinese patients with Charcot-Marie-Tooth disease type 1A

Charcot-Marie-Tooth disease type 1A (CMT1A) is the most common inherited peripheral neuropathy and currently lacks disease-modifying therapy. PXT3003, a low-dose oral combination targeting PMP22 overexpression, has shown efficacy in two trials, while one recent confirmatory trial...

Epigenetic reprogramming in SCNT embryos: from inefficient remodeling to precision enhancement

Somatic cell nuclear transfer (SCNT) is a unique reproductive engineering technique capable of conferring totipotency onto a somatic cell genome. It holds significant promise for animal germplasm conservation, livestock industry advancement, and biomedical research. Despite succe...

Human umbilical cord mesenchymal stem cell-derived exosomes alleviate neurocognitive disorders in chronic obstructive pulmonary disease by suppressing neuroinflammation

Abstract Background Patients with chronic obstructive pulmonary disease (COPD) frequently suffer from COPD-related neurocognitive disorders (COPD-NCDs), which severely impair their quality of life. Neuroinflammation is a key pathological mechanism, but effective therapies are sti...

Application of a Bioactive Compound 2,4-Di-tert-butylphenol in Nanoemulsion Form for Shelf-Life Extension of Cherry Tomatoes: From Microbial Inactivation to Quality and Safety Evaluation

Postharvest spoilage of cherry tomatoes caused by pathogenic microorganisms and oxidative browning leads to significant economic losses and food waste. Natural bioactive compounds are gaining increasing attention as alternatives to synthetic pesticides. In this study, a nanoemuls...