Harbin Medical University

Associations of key diet-quality indexes with trajectory of multimorbidity: a prospective study in the UK Biobank

Dietary patterns have been associated with the morbidity and mortality of individual non-communicable diseases(NCDs). However, the impacts of baseline dietary patterns among the initially healthy population on the progression from healthy to first non-communicable disease (FNCD),...

Latent profiles of health empowerment and associated factors among older adults hospitalised with stroke: a single-centre cross-sectional study

This study aims to explore the health empowerment of elderly ischemic stroke patients in China and analyze its associated factors. Ischemic stroke patients hospitalized in the Department of Neurology and Rehabilitation of a tertiary hospital in Daqing from June 2025 to March 2026...

Magnetotactic bacterial-reprogrammed TCR-macrophages for durable anti-tumor photoimmune therapy

Macrophage have shown great promise in the clinical treatment for head and neck cancer (HNC). However, macrophage therapies confront significant hurdles due to a deficiency of tumor-specific targets and tumor resistance. Herein, we report the development of a magnetotactic bacter...

Crystal structure of 9-(4-bromophenyl)-3,4,6,7,9,10-hexahydroacridine-1,8(2 H ,5 H )-dione, C 19 H 18 BrNO 2

Abstract C 19 H 18 BrNO 2 , monoclinic, P 2 1 / n (no. 14), a = 8.911(2) Å, b = 10.862(3) Å, c = 16.883(4) Å, β = 98.547(5)°, V = 1616.1(7) Å 3 , Z = 4, R gt ( F ) = 0.0449, wR ref ( F 2 ) = 0.1562, T = 296(2) K.

Adaptive intrathecal nanorobotics in mice and nonhuman primates for navigated CNS therapy

Intrathecal delivery for central nervous system (CNS) therapy lacks spatiotemporal control due to spinal canal anatomical constraints, especially at human scale. We developed an adaptive magnetic nanorobotic platform enabling multimode swarm mobility for in vivo spinal canal navi...

A Multi-omics Regulated Cell Death Framework Defines Immune Phenotypes and Guides Precision Therapy in Colorectal Cancer

Colorectal cancer (CRC) is molecularly and immunologically heterogeneous, contributing to variable treatment response. Because regulated cell death (RCD) intersects with tumor metabolism, immune regulation, and therapeutic susceptibility, we built an RCD-centered framework for CR...

A bibliometric analysis of ten years of international research on left ventricular assist devices

To conduct a bibliometric analysis of global Left Ventricular Assist Device (LVAD) research from 2015 to 2024, mapping its developmental trajectory, research hotspots, and academic impact. Publications from 2015 to 2024 were retrieved from the Web of Science Core Collection. Bibl...