Harbin Medical University

Crystal structure of 9-(4-bromophenyl)-3,4,6,7,9,10-hexahydroacridine-1,8(2 H ,5 H )-dione, C 19 H 18 BrNO 2

Abstract C 19 H 18 BrNO 2 , monoclinic, P 2 1 / n (no. 14), a = 8.911(2) Å, b = 10.862(3) Å, c = 16.883(4) Å, β = 98.547(5)°, V = 1616.1(7) Å 3 , Z = 4, R gt ( F ) = 0.0449, wR ref ( F 2 ) = 0.1562, T = 296(2) K.

Adaptive intrathecal nanorobotics in mice and nonhuman primates for navigated CNS therapy

Intrathecal delivery for central nervous system (CNS) therapy lacks spatiotemporal control due to spinal canal anatomical constraints, especially at human scale. We developed an adaptive magnetic nanorobotic platform enabling multimode swarm mobility for in vivo spinal canal navi...

A bibliometric analysis of ten years of international research on left ventricular assist devices

To conduct a bibliometric analysis of global Left Ventricular Assist Device (LVAD) research from 2015 to 2024, mapping its developmental trajectory, research hotspots, and academic impact. Publications from 2015 to 2024 were retrieved from the Web of Science Core Collection. Bibl...

A Multi-omics Regulated Cell Death Framework Defines Immune Phenotypes and Guides Precision Therapy in Colorectal Cancer

Colorectal cancer (CRC) is molecularly and immunologically heterogeneous, contributing to variable treatment response. Because regulated cell death (RCD) intersects with tumor metabolism, immune regulation, and therapeutic susceptibility, we built an RCD-centered framework for CR...