East China Normal University

Context-dependent functional diversity of dorsomedial posterior parietal neurons revealed by single-unit fMRI mapping during naturalistic viewing

Abstract The dorsomedial posterior parietal cortex (dmPPC) plays an important role in episodic processing by integrating sensory, cognitive, and motor information across distributed brain systems. However, how individual dmPPC neurons participate in large-scale functional organiz...

Activity Landscape Roughness Anticipates Machine-Learning Reliability Across Environmental Chemistry Endpoints

Abstract Machine learning increasingly supports chemical risk assessment under REACH, TSCA, and OECD QSAR frameworks, but random-split performance can be optimistic for structurally novel chemicals. We ask whether task difficulty can be anticipated before model training. EnvMolBe...

Pretrained 3D Molecular Representations Enable Data-Efficient Discovery of High-Energy-Density Fuels

High-energy-density hydrocarbon (HEDH) fuels are essential for aerospace propulsion, yet the design of such fuels is limited by the scarcity of reliable property data. In this work, we fine-tuned Uni-Mol, a pretrained three-dimensional (3D) molecular representation learning frame...

A Three-Layered Framework and Measurement Toolkit for Understanding Emotional and Relational Engagement with AI

As generative artificial intelligence (AI) becomes increasingly embedded in emerging adults’ academic, work, and social lives, interactions with AI increasingly involve emotional disclosure and relational engagement beyond instrumental use. However, empirical research has been co...

An ABA /auxin regulatory module controlled by nitrogen governs symbiotic organogenesis in the bryophyte species Ricciocarpos natans

Summary During the terrestrialization of plants c. 470 Ma, overcoming nitrogen limitation was a major evolutionary challenge. While nonvascular plants may acquire nitrogen through rhizoids and surface diffusion, symbiotic interactions likely provide an important strategy to overc...

Butterfly Proboscis‐Inspired Water‐Welding Strategy for Hollow‐Walled Hydrogel 3D Stents With Ultrahigh Mechanical Support Capacity

ABSTRACT Hydrogels have emerged as promising candidates for next‐generation implantable biomedical stents. However, the scalable fabrication of hydrogel three‐dimensional (3D) stents with sufficient mechanical support remains a major challenge, owing to the intrinsic flexibility...

Association between physical fitness index and executive function in Chinese Tibetan adolescents aged 10–12

OBJECTIVE: Examine the associations between Physical Fitness Index (PFI) and specific executive function (EF) subdomains (inhibitory control, working memory, cognitive flexibility) among Tibetan adolescents aged 10-12 years in China's high-altitude areas. METHODS: A total of 376...

Enantioselective and Divergent Synthesis of Propargylamides and Allenamides from Alkynyl Diazoketones and Anilines via Organocatalytic Wolff Rearrangements

Abstract Chiral allenes and alkynes are privileged scaffolds in natural products and pharmaceuticals. Although significant advances have been achieved in catalytic asymmetric synthesis from diazo compounds, selectively achieving high levels of both enantioselectivity and regiosel...

Climate extremes are associated with crime dynamics in China

While the societal implications of climate extremes have received considerable attention, the specific associations with crime dynamics remain unclear. Leveraging a unique nationwide crime panel dataset (over 8.6 million) parsed via large-scale textual analysis, we capture detail...

Overcoming polarization-breakdown trade-off via hydrogen bonding-modulated molecular stacking in high-temperature high-energy-density flexible dielectric

Flexible dielectrics suffer from an inherent polarization-breakdown trade-off. Herein, we propose a hydrogen bonding-modulated molecular stacking strategy to improve high-temperature capacitive energy storage performance. A series of polyetherimide copolymers with tunable hydroge...

Coarse-Grained Nonadiabatic Dynamics in Disordered Condensed Phases

Abstract The mechanisms underlying critical energy-gap fluctuations and nonadiabatic dynamics in disordered condensed phases remain elusive, and their accurate simulation poses a challenge due to the inherent complexity of these systems. In this study, we make the first attempt t...

Perceived school-wide teacher-student relations and teacher job satisfaction: An affective events theory analysis of Shanghai teachers

Teachers’ perceptions of teacher-student relations in their school are linked to their job satisfaction, but whether positive teaching-related emotion constitutes a statistical indirect association between them, and whether school leadership context alters it, remains unclear. Us...

Atomistic simulation of crystal–melt coexistence interfaces under tangential flow

Fluid motion is ubiquitous in solidification, yet its atomistic influence on the immediate solid-liquid interfacial region remains difficult to quantify. Here, we develop an atomistic simulation framework for maintaining solid-liquid coexistence interfaces under imposed tangentia...

Reconfigurable Terahertz Multi‐Harmonic Dual‐Combs

ABSTRACT Dual‐comb spectroscopy, constructed from two frequency combs with slightly different repetition frequencies, enables real‐time and high‐precision measurements without mechanical scanning. In the terahertz (THz) spectral range, dual‐comb techniques provide a powerful tool...

An East Asian blood eQTL meta-analysis highlights ancestry-matched eQTL resources for complex-trait genetics

Abstract Expression quantitative trait loci (eQTLs) link genetic variation to gene regulation and complex traits, yet population-scale blood eQTL resources remain limited in East Asian populations. We mapped cis-eQTLs in 1,005 Chinese individuals and meta-analysed them with a Jap...

How testosterone administration affects social rank perceptions: A double-blind, placebo-controlled study

Navigating social hierarchies is fundamental to human survival and reproductive success, relying heavily on the accurate perception of social rank. However, the neuroendocrine mechanisms underlying this perception remain largely uncharted. Given testosterone’s established role in...

LoMax: LLM‐Driven Local Code Optimization for MaxSAT Solvers

ABSTRACT The Maximum Satisfiability (MaxSAT) problem is a fundamental combinatorial optimization task, and state‐of‐the‐art solvers rely on decades of expert‐engineered heuristics and low‐level micro‐optimizations to achieve competitive performance. While recent Large Language Mo...

Visible‐Light Photocatalytic Functionalization of Aryl Chlorides and Fluorides

ABSTRACT Aryl chlorides and fluorides are inexpensive and readily available feedstocks; however, the high bond dissociation energies and low polarizability of C Ar ─X (Cl, F) bonds have long posed significant challenges to classical thermal activation, which is often harsh and po...

A Triple‐Site Engineered Heterojunction Photocatalyst for Full‐Spectrum NH 3 Synthesis via Synergistic Promotion of Water Oxidation and Nitrate Reduction

ABSTRACT Photocatalytic nitrate reduction reaction (NitRR) represents a sustainable approach to convert nitrate pollutants to valuable NH 3 . However, the performance of state‐of‐the‐art photocatalysts is hampered by insufficient near‐infrared (NIR) light utilization and sluggish...

Sustained algal-bacterial interactions promote accumulation of recalcitrant particulate carbon with accelerated radiocarbon aging signatures

Algal-bacterial interactions regulate the production and fate of marine particulate organic carbon (POC), yet their capacity to generate long-lived carbon sinks remains unclear. Using a two-year, nutrient-self-sustaining co-culture of Synechococcus and its mutualistic microbiota,...