East China Normal University

A Cumulative Ordered Spike-and-Slab Prior for Adaptive Dimension Selection in Joint Latent Space Models

Network models are increasingly vital in psychometrics for analyzing relational data, which are often accompanied by high-dimensional node attributes. Joint latent space models provide an elegant framework for integrating these data sources by assuming a shared underlying latent...

Automated pancreatic segmentation and regional fat quantification suggest tail fat association with type 2 diabetes

Abstract Accurate pancreatic segmentation and quantitative assessment are crucial for investigating diabetes pathogenesis. Despite advancements in deep learning, regional segmentation remains challenging due to the organ’s anatomical complexity. This study established a two-stage...

GPR87 protects UVB-damaged skin by coordinating antioxidant, DNA repair, and anti-inflammatory responses via Nrf2 and PI3K/AKT-NF-κB pathways.

data further showed that GPR87 deficiency aggravated inflammatory responses and cyclobutane pyrimidine dimer (CPD) accumulation while attenuating apoptosis in skin cells. Moreover, GPR87 facilitated CPD clearance by regulating the expression and ubiquitination of XPC, a key compo...

Abuse, neglect, and adolescent depression: distinct symptom networks and potential intervention targets

Childhood abuse and neglect may be associated with depressive symptoms through distinct developmental pathways, yet little is known about whether depressive symptom networks differ across trauma profiles. This study compared depressive symptom networks across abuse-only, neglect-...

Global Projections of Coral Reef Sediment Dissolution in the 21st Century

Abstract Coral reefs build carbonate frameworks, but ocean acidification threatens to reverse this role by accelerating dissolution of permeable reef sediments. We combined Earth system model projections across five emission pathways with an aragonite saturation state‐dissolution...

Maternal childhood maltreatment and adolescent internalizing problems: Intergenerational pathways via emotion regulation difficulties and offspring maltreatment

Background Research has established the intergenerational transmission of maternal childhood maltreatment to offspring internalizing problems. However, the potential indirect pathways underlying this intergenerational association remain under-explored, particularly regarding how...

From Potential to Reality: Gaps in Realizing Human–AI Complementarity in Educational Tasks

Human–artificial intelligence collaboration (HAIC) is emerging as a transformative approach in education, yet empirical evidence regarding its impact on educational task performance remains limited. This study adopts a complementarity perspective and distinguishes three types of...

Mammalian DNA maintenance methylation depends on histone but not PAF15 ubiquitination

In mammals, DNA methylation is an essential inheritable epigenetic modification maintained by the DNMT1-UHRF1 machinery in a UHRF1 E3 ubiquitin ligase-activity-dependent manner. UHRF1-catalyzed histone ubiquitination and PAF15 ubiquitination have been proposed to recruit DNMT1 to...

Adversarial attacks on medical hyperspectral imaging exploiting spectral-spatial dependencies and multiscale features

Abstract Medical hyperspectral imaging (MHSI) has demonstrated considerable promise in disease diagnosis by capturing spectral-spatial information of tissues. While deep learning has substantially improved MHSI classification accuracy, its robustness remains limited due to the we...

Cu-Catalyzed Cross-Coupling of (Hetero)Aryl Halides with Malonates: One-Pot Assembly of α-Arylacetic Acid Scaffolds

Abstract A direct synthesis of α-arylacetic acids from (hetero)aryl chlorides and bromides and malonates via Cu/oxalamide-catalyzed cross-coupling with tandem hydrolysis and decarboxylation is described. Enabled by tailored oxalamide ligand L4, the reaction proceeds smoothly unde...

SelO functions as a tumor suppressor through AMPylating Cdk5rap3

Cell fate is governed by signaling pathways involving diverse protein modifications. However, how protein AMPylation mediates signal transduction in mammalian cells remains largely unexplored. We demonstrate that the protein adenylyltransferase, SELENOO (SelO), is induced by chem...

Topological Reinforcement of Rhizosphere Microbial Networks Facilitates the Invasive Superiority of Spartina anglica

Rhizosphere microbial interaction patterns underpin the resilience and dominance of invasive plants in fluctuating coastal salt marshes. We compared the rhizosphere microbial communities of the invasive Spartina anglica and the native Spartina maritima across varying distances fr...

Comparing different pathways to primary mathematics teaching using teacher competence measurement of the TEDS research program

Abstract Teacher shortages are a major challenge worldwide, especially in mathematics. In response, many countries have implemented measures to recruit graduates from fields other than mathematics teaching for alternative pathways into the teaching profession, offering an alterna...

Experimental evolution reveals biphasic adaptation of Bacillus subtilis to long-chain fatty acid stress

Gram-positive bacteria like Bacillus subtilis are typically sensitive to long-chain fatty acids (LCFAs), which serve as both nutrients and antimicrobials, posing an ecological paradox regarding their survival in lipid-rich environments. We experimentally evolved B. subtilis for ~...

A 400‐Year Antarctic Ice‐Core Perchlorate Record Reveals Variability in Stratospheric Chlorine Chemistry

Abstract Perchlorate (ClO 4 − ) in polar ice preserves past chlorine oxidation chemistry; however, multi‐centennial Antarctic ClO 4 − records and the mechanisms controlling their variability remain poorly constrained. Here, we present the first 400‐year (1616−2016) ClO 4 − record...

Integrated marine spatial planning for Chonburi Province, Thailand: Addressing pollution, blue carbon, and conservation

While Marine Spatial Planning (MSP) is globally recognized as a strategic tool for ocean governance, its implementation in tropical coastal regions faces distinct challenges stemming from fragmented governance and acute conflicts between traditional livelihoods and modern industr...

Breaking the Diffusion–Dispersion Trade‐Off: Subnanometric MoO 3 Clusters in Interzeolite Transformation Intermediates for Oxidative Desulfurization With H 2 O 2

ABSTRACT Overcoming the intractable trade‐off between restricted bulky molecule diffusion in microporous zeolites and poor active‐metal dispersion on mesoporous supports remains a formidable challenge, particularly in the deep oxidative desulfurization of fuel oils. Herein, by st...

Social Functioning Profiles in Children with Autism Spectrum Disorder in China: A Preliminary Identification of Subtypes

Children with autism spectrum disorder (ASD) exhibit considerable heterogeneity in social functioning, suggesting the existence of distinct latent subtypes. A total of 479 Chinese children diagnosed with ASD (Mage = 9.338 years) were assessed using the Mandarin translation of the...

Morphology and Phylogeny of Four Marine Scuticociliates (Protista, Ciliophora), with Descriptions of Two New Species: Pleuronema elegans spec. nov. and Uronema orientalis spec. nov.

This dataset contains the digitized treatments in Plazi based on the original journal article Pan, Xuming, Huang, Jie, Fan, Xinpeng, Ma, Honggang, Al-Rasheid, Khaled A. S., Miao, Miao, Gao, Feng (2015): Morphology and Phylogeny of Four Marine Scuticociliates (Protista, Ciliophora...

Surface Biogeochemical Regimes Shape Microplastic Abundance in the Eastern Indian Ocean

Abstract Open-ocean microplastic (MP) abundance is commonly reported as a contamination metric, but surface concentrations may reflect environmental redistribution, dilution, and retention in addition to source exposure. Here, we investigated surface MPs across 43 stations in the...