Centre National de la Recherche Scientifique

Unraveling HBV Life Cycle by Fluorescent Microscopy Imaging

The hepatitis B virus (HBV) is a worldwide hepatotropic virus despite the availability of a highly effective vaccine. Currently, the most efficacious treatment against HBV infection is the use of interferon and nucleos(t)ide analogs, which effectively suppress viral replication b...

Electrospun Nanofibers Loaded with Verbena officinalis Extract as Multifunctional Bioactive Wound Dressings

Background/Objectives: Verbena officinalis has long been used in traditional medicine for treating skin disorders, yet its potential in advanced wound-dressing systems remains insufficiently explored. This study aimed to characterize V. officinalis extracts obtained using differe...

Conserved dimerization architecture in C‐type lectins from virus‐vector mosquitoes

Abstract C-type lectins (CTLs) play key roles in innate immunity and microbial carbohydrate recognition. In the disease vector mosquito Aedes aegypti , the CTLD-S family comprises 34 soluble CTLs whose members are implicated in flavivirus dissemination and microbial homeostasis,...

Measuring Ocean Surface Waves

Abstract Propagating waves on the ocean surface can be represented as a stochastic process whose statistics are characterized by a spectrum. This paper reviews methods for measuring the wave spectrum and related quantities. Observations begin by sensing fluid dynamical properties...

Macroevolutionary dynamics of Androsace s.l . (Primulaceae) across the Northern Hemisphere

Abstract Mountain regions of the Northern Hemisphere harbor exceptional biodiversity, yet the processes underlying species diversification and migration among these regions remain poorly understood. This study investigates the macroevolutionary dynamics of Androsace s.l ., a genu...

Seed-based functional connectivity of the anterior cingulate cortex and the posterior insula predicts placebo analgesia in Parkinson’s disease

Chronic pain affects up to 80% of people with Parkinson’s disease (PD) and remains difficult to treat. Functional brain connectivity can predict analgesic response in other conditions, but has not been explored in PD. To assess whether baseline resting-state functional connectivi...

An airborne in-situ dataset of cloud microphysical properties in supercooled large droplet icing conditions

Abstract. Detailed and comprehensive data sets on microphysical cloud properties in icing conditions are rare. In April 2023, fifteen research flights were performed with the SAFIRE ATR 42 research aircraft during the SENS4ICE-EU airborne measurement campaign over France and adja...

Genetic distance and pollinator sharing shape divergence in floral volatiles in closely related dioecious Ficus species

Abstract Premise Floral scent is central to host recognition in the fig–fig wasp mutualism, yet how scent divergence relates to pollinator sharing among closely related dioecious Ficus species remains unclear. Methods We analyzed volatile organic compounds (VOCs) from four pairs...

Agreement of Hematologic Measurements Between Jugular and Coccygeal Puncture Sites in Cattle

ABSTRACT Background In bovine medicine, venipuncture is commonly performed at either the jugular or coccygeal vein. Although the coccygeal site is often preferred for practical reasons, sampling sites are inconsistently standardized in scientific studies. It is therefore importan...

A framework to compare the performance of spatial disaggregation methods of statistical climate downscaling in South America

Study region Chile and South America. Study focus Climate change is simulated at a coarse scale with General Circulation Models. Impact and regional studies require downscaling to increase spatial resolution. Several downscaling methods exist, but most studies do not analyze or c...

Atmospheric forcing and ocean preconditioning for dense shelf water cascading in the northwestern Mediterranean

<title>Abstract</title> Dense shelf water cascading (DSWC) in the northwestern Mediterranean Sea occurs due to the densification and overflow of shelf water in winter. This process ventilates the deep basin with waters that can be denser than those generated by open-ocean convect...

Accelerating charging dynamics of electric double-layer capacitors

Electric double-layer capacitors (EDLCs), consisting of an ionic fluid between two metallic electrodes, are electrochemical energy storage devices complementary to batteries, allowing for a faster charge/discharge. The charging dynamics in response to a voltage step features a va...

Tailoring Liquid Crystalline Self‐Assembly and Photophysical Properties of Unsymmetrical Fluorenones via Polar Terminal Groups

ABSTRACT In this work, a series of novel unsymmetrical fluorenone derivatives bearing various head groups (H, Br, NO 2 , NH 2 , and CN) was synthesized and investigated with respect to their mesomorphic and photophysical properties. Depending on the head group, SmA, N, or SmC pha...

Gluon production in the color glass condensate from BCFW recursion

A bstract In the Color Glass Condensate framework, the colliding projectiles are described as classical color currents. Gluon production at leading order in the coupling is obtained from the retarded solution of the classical Yang-Mills equations, with these currents acting as so...

Evaluating urban heat adaptation strategies for extreme heatwaves in complex terrain: A case study of Grenoble, France

Urban heat adaptation strategies are critical for mitigating the impacts of ex- treme heat events in cities, particularly as climate change exacerbates their intensity and frequency. This study evaluates a set of adaptation strategies during the 2023 heatwave in Grenoble, France,...

Development of antibacterial wipes coated with nanofibers made from nisin and polyvinyl alcohol

Nosocomial infections caused by Staphylococcus aureus ( S. aureus ), a major pathogen that colonizes human skin, are a significant cause of morbidity and mortality. Effective management of S. aureus is essential, especially given the rising threat of antibiotic resistance. Innova...

Macrophage heterogeneity in human secondary lymphoid organs

Abstract Macrophages play a major role in immune responses and in the maintenance of tissue homeostasis. Most of our knowledge of macrophage biology comes from mouse studies, which have revealed the existence of distinct subpopulations differing in origin, life cycle and tissue-s...

Hydroelastic slamming of tubular structures: Experimental and theoretical studies

Hydroelastic slamming loads are of primary importance for the design of marine and offshore structures involving slender flexible structures. In this study, a combined experimental and theoretical investigation of the water impact of tubular structures is carried out. First, a de...

Thermodynamic characterization of Lewis acid–base interactions on carbon nanomaterials: Validation and Universality of the Hamieh five-parameter model

Understanding the Lewis acid–base properties of carbon materials is essential for predicting adsorption behavior, catalytic performance, and interfacial interactions. In this work, eight carbon materials—graphene, graphene oxide, reduced graphene oxide, untreated carbon fiber, ox...

Visible-Light-DrivenPorphyrin/ZnO Nanohybrids forUltrasensitive Room-Temperature Triethylamine Sensing

Abstract Real-time monitoring of toxic triethylamine (TEA) at room temperature remains a significant challenge for metal oxide chemiresistors due to their typically high-power consumption and thermal requirements. This work presents a highly responsive, visible-light-activated ga...