Aarhus University

Energy and spatial spillovers: How renewable and non-renewable energy impact the environment?

Atmospheric emissions in one location can significantly affect adjacent regions, creating spatial dependencies. If ignored, it may biased empirical estimates of environmental degradation. This study employs spatial econometric techniques to measure the indirect (spillover) effect...

Global analysis of thermal and chemical denaturation using CheMelt : Thermodynamic dissection of highly thermostable de novo designed proteins

ABSTRACT De novo protein design often produces thermostable proteins that denature above 100 °C, which complicates the analysis of their stability. Thermostable proteins can be unfolded by combined chemical and thermal denaturation followed by global analysis of multiple melting...

Design of Experiments for Diverse Carbon Isotope Labeling with Aryl Thianthrenium Salts

Abstract A method for accessing structurally diverse carbon-isotope-labeled products from aryl thianthrenium salts has been established. The use of near-stoichiometric amounts of ex situ-generated carbon monoxide along with simple, air-stable palladium catalysts allows for the sy...

Biochar and compost application synergistically enhance soil microbial activity in coastal savanna Acrisol

The use of organic fertilizers such as compost and biochar have received much research attention but their potential synergistic effects on soil biological properties have not been sufficiently investigated. This study investigated the effects of combined application of empty fru...

Can they agree on what to disagree about? Patterns of issue agenda setting in the 2020 US presidential election

American voters, politicians, and media are increasingly hostile toward out-partisans and frequently disagree about the content of policies. This development raises an even more fundamental question about the nature of politics in highly polarized societies: Can the political act...

Nurses' Perspectives on a Communication Model Between Providers and Mechanically Ventilated Patients in the Intensive Care Unit

ABSTRACT Background Communication with mechanically ventilated patients in intensive care is complex. Decades of research demonstrate that communication barriers are commonly experienced and one of the most challenging experiences during an intensive care stay. Support for the he...

An Arctic climatology of particle number size distributions and cloud condensation nuclei during warm and moist intrusions

Abstract Recent studies indicate that warm and moist intrusions are significant sources of aerosols in the Arctic. Yet their contribution to different aerosol particle size modes, cloud condensation nuclei (CCN), and droplet number concentrations ( N d ) remains largely unconstra...

Metformin Pharmacogenetics in Heart Failure Patients with Reduced Ejection Fraction: Impact on Metformin and Growth Differentiation Factor-15 Plasma Levels

This study assessed plasma metformin trough steady-state concentrations and plasma growth differentiation factor-15 (GDF-15) in patients with heart failure with reduced ejection fraction (HFrEF), and evaluated the effect of genetic variations in OCT1, OCT2, MATE1, and MATE2-K on...

Repeated exposure to viral and bacterial danger signals in Parkin deficient mice induces inflammation but fails to trigger parkinsonism

Experimental models of Parkinson's disease (PD) traditionally involve direct perturbations of the functioning of dopamine (DA) neurons. However, PD is increasingly recognized as multifactorial in origin and involving both cell-autonomous vulnerability factors and non-cell-autonom...

Persisting perceptual abnormalities in psychedelic users are associated with conditioned hallucinations and impaired sensory processing

Abstract Serotonergic psychedelics (SP) are increasingly used in clinical research and naturalistic settings, but their psychotic-like side effects, including persisting perceptual abnormalities (PPAs), are poorly understood. Psychosis-associated hallucinations are associated wit...

Müllerian Duct Aplasia in a Girl With SMARCB1 ‐Related Coffin–Siris Syndrome: A Rare Co‐Occurring Anomaly

ABSTRACT Genetic etiologies of Müllerian aplasia (Mayer–Rokitansky–Küster–Hauser syndrome) remain poorly understood. Identification of patients with monogenic syndromes presenting with Müllerian aplasia may help improve our knowledge of the underlying biology. We investigated a 1...

Exploring the Feasibility and Acceptability of Compassion and Mindfulness Training for Adolescents With Type 1 Diabetes and Their Caregivers

AIM: To examine the feasibility and acceptability of mindfulness training for adolescents with Type 1 diabetes (T1D) and compassion training for caregivers. METHODS: Adolescents aged 12-17 years with T1D, and their caregivers were recruited from two diabetes centres between 2022...

Percolation‐Driven β ‐Relaxation Enables Resonant Acceleration of Crystallization in Amorphous Phase‐Change Materials

ABSTRACT Amorphous phase‐change materials enable fast and reversible switching in optical and electronic devices, yet crystallization kinetics are still controlled primarily through empirical thermal protocols. Here we identify a microscopic picture governing crystallization in t...

Long-term Trends in Upper Gastrointestinal Bleeding and Ischemic Outcomes after Myocardial Infarction

Abstract Aims Invasive management and intensive antithrombotic regimens have decreased ischemic risk after myocardial infarction (MI) at the cost of more bleeding. Of particular concern is upper gastrointestinal bleeding (UGIB), which is both common and preventable, yet not well...

Major adverse cardiac events and mortality associated with ADHD and its treatment in adults with type 2 diabetes: a multi-national cohort study

Abstract Background Attention-deficit/hyperactivity disorder (ADHD) has been linked to elevated risk of type 2 diabetes (T2D). However, the impact of ADHD and ADHD medication use on prognosis and health outcomes in T2D remains unclear. This study investigates the associations of...

Genetic and pharmacologic inhibition of Keap1 dampens the pro-fibrotic program in human hepatic stellate cells

Abstract The increasing prevalence of chronic liver diseases (CLDs) is a global health concern. CLDs can cause fibrosis, and there is an urgent need for antifibrotic agents. The primary driver of fibrogenesis, transforming growth factor beta 1 (TGF-β1), activates hepatic stellate...

Functional central limit theorem for topological functionals of Gaussian critical points

We consider Betti numbers of the excursion of a smooth Euclidean Gaussian field restricted to a rectangular window, in the asymptotics where the window grows to Rd. With motivations coming from topological data analysis, we derive a functional central limit theorem where the vary...

Using the Danish Administrative Registers to Define Mental Disorders: Potential and Limitations of Using Different Data Sources

BACKGROUND: Although the Danish health registers provide rich data for epidemiological mental health research, the comparability of findings is hindered by different definitions of mental disorders across studies. We aimed to describe different approaches taken by researchers to...

Potentially inappropriate prescribing in individuals with type 2 diabetes mellitus: a Danish nationwide study

Abstract Aim We aim to describe the prevalence of potentially inappropriate prescribing (PIP) in individuals with type 2 diabetes mellitus. Furthermore, we aim to explore associations between PIP and different individual-level factors. Subject and methods This was a nationwide re...

Unpacking Roman trade: a quantitative study of amphora circulation in the Western provinces

Ceramic amphorae provide clues to the movement of foodstuffs within the Roman Empire and can therefore act as a useful proxy for economic productivity. Here, the authors present the results of a large-scale quantitative analysis of amphora frequency data from 254 excavations cond...