Research works

Swimming and Electrical Muscle Stimulation Attenuate Early Pulmonary Vascular Remodeling Without Restoring Circulating Irisin in Monocrotaline-Induced Pulmonary Hypertension

Pulmonary arterial hypertension (PAH) is a progressive and life-threatening disease with limited therapeutic options. Exercise exerts beneficial cardiovascular effects partly through myokines such as irisin. This study investigated the preventive/early-intervention effects of swi...

Distinctive subcortical connectivity predicts treatment response in first-episode schizophrenia

Background Subcortical regions are widely implicated in the pathological mechanisms and treatment of schizophrenia, and accumulating evidence, including our prior findings, suggests that subcortical functional dysconnectivity is closely associated with treatment response. Accordi...

Effects of SO(3) Action Representations on Observation-based Imitation Learning for Robotic Manipulation

This study examines how 3D rotation action representations affect observation-based imitation learning for robotic manipulation. In behavioral cloning from observation (BCO), expert actions are unavailable, so an inverse dynamics model (IDM) estimates pseudo-actions from consecut...

Label Refinement for Robot Vision Object Detection via Dynamic Threshold Estimation and Optimal Refinement Model Selection

This study proposes a label refinement method for robot vision object detection utilizing multi-model-based dynamic threshold estimation. The ultimate goal of this research is to improve the recognition accuracy and robustness of intelligent waste-sorting robotic arm vision syste...

Investigating predictive value of Q-waves and inverted T-waves in anterior STEMI patients undergoing primary PCI: a prospective cohort study

This study investigated the prognostic role of pathological Q waves and T-wave inversions (TWI) in patients with anterior ST-elevation myocardial infarction (STEMI). Prospective cohort study of 658 anterior STEMI patients undergoing primary percutaneous coronary intervention (PCI...

Artificial intelligence anxiety: a narrative review of psychiatric conceptualization and clinical management

Artificial intelligence (AI) is gradually permeating every aspect of daily life. AI is now more than a mere tool; it significantly influences individual capabilities, professional values, social status, and our perspectives on the future. Amid these AI-driven changes, the concept...

Milk-derived exosomes (MDEs) as emerging nanotherapeutics in regenerative medicine

Milk-derived exosomes (MDEs) are naturally occurring nanoscale extracellular vesicles with unique biocompatibility, stability, and intrinsic capacity to carry diverse bioactive cargoes such as proteins, lipids, and nucleic acids. Recent studies have underscored their remarkable t...

Culturally adapted wearable mobile health intervention for physical activity and cognitive function in middle-aged Koreans: a pilot feasibility study

BACKGROUND: Middle adulthood (45-64 years) represents a critical window for the primary prevention of cognitive decline and chronic diseases, with physical activity capable of reducing later cognitive decline by 20% to 35%. However, most evidence on mobile health (mHealth) interv...

Technical note: reconstructing dose distributions from manually planned electron boosts in breast radiotherapy

Purpose In breast radiotherapy, delivery of manually-calculated electron boosts limits retrospective dose–response analyses as dose distribution is unavailable. This work evaluates the feasibility of reconstructing dose distributions from manually planned electron boosts in breas...

A Retrospective Clinical Study of 44 Cases of Parapharyngeal Space Tumors

副咽頭間隙腫瘍はまれな疾患であり，治療方針の決定に苦慮することが多い。本検討では，手術適応の決定に関連する臨床因子を探索することを目的として，当院で診療した44例を後方視的に解析した。初回治療方針により手術群16例，経過観察群28例に分類し，性別，年齢，症状，腫瘍体積，腫瘍位置，FNAC施...

Elucidating relationships among upward social comparison on social networking sites (SNSs), depressive symptoms, and SNS addiction in college students: insights from structural equation modeling and network analysis

With the burgeoning prevalence of social networking sites (SNSs), the likelihood of upward social comparison on SNSs has concomitantly escalated, particularly among college students. Notably, upward social comparison on SNSs has been linked to negative emotions and problematic be...

Coronavirus disease 2019 vaccination and reduced severity-related outcomes in high-risk groups in Thailand during the Omicron period

Despite the coronavirus disease 2019 (COVID-19) booster vaccination, individuals with comorbidities continue to experience disproportionately severe COVID-19 disease and adverse outcomes. Evidence on associations between vaccination status and clinical outcomes among high-risk gr...

Viscoelastic testing and blood product utilization: a prospective study on associations and predictors of high transfusion needs in living donor liver transplantation

Background: Anticipation of massive blood transfusion (MBT) can enhance patient care, operating room logistics and planning. Rotational thromboelastometry (ROTEM), evaluates whole blood hemostasis from initiation to hemolysis. This study aimed to determine the role of ROTEM in li...

Is a tracheoesophageal fistula management still a challenge in low resource setting? Case report of rare type D tracheoesophageal fistula and literature review

Management of the common TEF cases have been with low promising outcomes in low resourced countries as compared to developed countries. Type D Tracheoesophageal fistula is a most rare condition whose management experience, challenges and outcomes are not adequately documented esp...

Enterprise Defect Analysis Methodology (EDAM) – Version 2.0 – Phase 2: Enterprise Defect Classification

Enterprise Defect Analysis Methodology (EDAM) is an evidence-first methodology for enterprise software quality engineering. EDAM transforms historical enterprise defect repositories into trustworthy evidence before analysis begins. The methodology establishes a structured, repeat...

HierCache-RAG: Fast Retrieval-Level Caching for GraphRAG

Graph Retrieval-Augmented Generation (GraphRAG) improves multi-hop reasoning in Large Language Models (LLMs) by grounding generation in knowledge-graph structure, but most systems re-traverse the graph on every query, wasting computation whenever queries repeat or overlap semanti...

The Biomass Distribution on Earth

<p>This resource uses an interactive Voronoi diagram to explore global biomass and abundance data across major taxonomic groups, based on Bar-On, Phillips, and Milo (2018). It compares organisms across environments and measurement types, with guided activities for additiona...

Fluid Dynamics of Spacetime: Spacetime Currents as an Alternative to Dark Matter and Galactic Rotation

This paper proposes an alternative theoretical framework for understanding large-scale cosmic dynamics. We postulate that spacetime is not an inert void, but rather a fluid with an intrinsic and constant density (ρ_ST). In this conception, moving mass and energy (described by the...

HEPE: Hardware-Enforced Policy Engine — Formal Specification and Verification

Updated version of EHOX formal verification and engineering artifact. Creator corrected to Gerhard Hirschmann (EHOX Systems, St. Johann in Tirol, Austria). Original record: 21818830. Hardware: AMD Kria KV260, ARM Cortex-R5F, ZynqMP XCZU5EV. Formal verification: CBMC 198/0, Z3 SMT...

EHOX Universal Pitch Deck v3 — Silicon-Level AI Governance for Defence, Aerospace, Medical, Mobility

Updated version of EHOX formal verification and engineering artifact. Creator corrected to Gerhard Hirschmann (EHOX Systems, St. Johann in Tirol, Austria). Original record: 21818828. Hardware: AMD Kria KV260, ARM Cortex-R5F, ZynqMP XCZU5EV. Formal verification: CBMC 198/0, Z3 SMT...