Research works

UV Inactivation of Bacteria and Viruses on Surfaces: Mechanistic Insights and Testing Method Comparisons

Abstract Accurate evaluation of UV surface disinfection requires understanding of the impacts of testing methods and microbial characteristics on observed inactivation performance. This study evaluated the surface inactivation kinetics of two bacteria and two bacteriophages using...

APOE Genotype–specific Cognitive Response to Aerobic Exercise in Postmenopausal Women with Breast Cancer

Cognitive symptoms are common in postmenopausal women treated for breast cancer (BC). In general and in BC, the Apolipoprotein E 4 allele ( APOE4) is linked to lower cognition and accelerated cognitive decline, but exercise generally benefits cognition. The purpose of this study...

Dupilumab as Add‐On Therapy for JAK Inhibitor‐Relapsed Pediatric Alopecia Areata: A Case Series

ABSTRACT A retrospective case series evaluated dupilumab as add‐on therapy in 15 children with severe alopecia areata who relapsed after achieving SALT80 with Janus kinase inhibitors. At Week 12, the median improvement in SALT score from baseline was 59.0%. Among the 13 patients...

Representation of ethnic minorities: visual rhetoric on the covers of Nationality Pictorial (1955–2024)

This article examines the visual representation of ethnic minorities on the covers of Nationality Pictorial (1955–2024), a state-level pictorial in China devoted to minority affairs. Drawing on a longitudinal dataset of 735 covers and a multimodal discourse analysis framework, th...

Skin tear prevention and management among frail older adults in a Taiwanese long-term care facility: a best practice implementation project.

INTRODUCTION: Skin tears are common among frail older adults in long-term care and remain inconsistently managed despite international guidance. OBJECTIVES: This evidence implementation project aimed to enhance compliance with evidence-based skin tear prevention and management pr...

Muscle synergy characteristics during hands-and-knees crawling in children aged 4–6 years

Hands-and-knees crawling requires complex multi-joint coordination, managed by the central nervous system (CNS) via muscle synergies. While infant crawling is well-studied, neuromotor control in 4–6-year-olds remains under-investigated. This study examined the spatiotemporal cons...

Aerodynamic and surface pressure characteristics of quasi two-dimensional wings featuring leading-edge flags: An experimental and statistical approach

The present study explores a passive flow control technique utilizing leading-edge flags (with and without serrations) over the airfoil to improve the performance of the airfoil. These flags are attached to the leading-edge of the airfoil that oscillates naturally in response to...

Suppression of PKM2 by Leonurine Attenuates Alcoholic Hepatitis Through Regulating Glycolytic Reprogramming

Alcoholic hepatitis (AH) is a liver disease caused by long-term heavy drinking. In the early stages, it usually manifests as fatty liver, which can then develop into liver fibrosis and cirrhosis. Kupffer cells are liver resident macrophages and the effect of glycolytic reprogramm...

Data Physics & Cyber-Physical Systems - Part VI: Thermo-Algorithmic Determinism and Logical Cavitation: A New Data Physics Paradigm for Frontier AI Clusters

Abstract. As artificial intelligence clusters reach gigawatt-scale, conventional facility engineering encounters hard physical barriers. The IT industry, which traditionally treats software as abstract logic, must confront the reality that code is energy shaped into information....

Effect of the Aggregate Composition of the Arable Layer on Winter Wheat Yield Under Micro-Plot Experiment Conditions

This study focuses on the physical modelling of the aggregate composition of the arable soil horizon in order to evaluate its effect on the yield of winter wheat. It is hypothesised that the maximum possible yield can be achieved under the soil and climatic conditions of southern...

Dual targeting of EGFR signaling and microtubule dynamics enhances replication-associated cellular stress and suppresses tumor growth in gefitinib-resistant non-small cell lung cancer

Acquired resistance to epidermal growth factor receptor (EGFR)-targeted therapy remains a major obstacle in the treatment of EGFR-mutant non-small cell lung cancer (NSCLC). This study investigated whether repurposing mebendazole (MBZ), a microtubule-disrupting agent, could restor...

EDN1 GENE POLYMORPHISM AS A GENETIC PREDISPOSING FACTOR FOR UNSTABLE ANGINA

Unstable angina is one of the most clinically significant manifestations of ischemic heart disease, the devel­opment of which is determined by the interaction of endothelial dysfunction and genetic predisposition. The aim of the study was to investigate the association between th...

Autoimmune and inflammatory diseases associated with T-cell clonal expansion

Autoimmune and inflammatory diseases (AID) result from a breakdown of immune tolerance, often driven by T-cell dysregulation and sometimes associated with clonal T-cell expansion. While T-cell large granular lymphocyte leukemia (LGL-L) is a well-defined clonal disorder commonly a...

A Homozygous ALCAM–CBLB Deletion at 3q13.11‐q13.12 Defines a Candidate Novel Oculo‐Skeletal‐Immune Contiguous Gene Deletion Syndrome

ABSTRACT To our knowledge, we report the first combined homozygous deletion of ALCAM and CBLB at 3q13.11‐q13.12. The patient, a 14‐year‐old boy born to consanguineous parents, had a multisystem phenotype with severe congenital ocular and craniofacial anomalies, early‐onset osteop...

Clinical Factors Associated with Diagnostic Delay in Axial Spondyloarthritis in Saudi Arabia: A Retrospective Cohort Study

Background/Objectives: Diagnostic delay remains a major challenge in axial spondyloarthritis (axSpA), yet factors associated with delay in Saudi Arabia and the Arabian Gulf remain poorly characterized. We examined clinical factors associated with diagnostic delay in a single-cent...

Sputum eosinophil and neutrophil activation biomarkers in severe asthma

Background Asthma is characterized by different inflammatory phenotypes. We hypothesized that sputum eosinophil-derived neurotoxin (EDN), and myeloperoxidase (MPO) or interleukin-8 (IL-8) levels improves the granulocytic characterization of asthma compared to sputum granulocyte c...

High‐Purity Hydrogen Production From Water–Gas Shift Reaction in a High‐Temperature Polymer Electrolyte Membrane Electrolyzer

ABSTRACT The water–gas shift reaction (WGSR) is a critical pathway for hydrogen production, yet current methods face trade‐offs between purity and scale. Thermocatalytic WGSR achieves high product purity but requires energy‐intensive gas separation, while room‐temperature electro...

Impact of Digital Place-Based Policies on the Inclusive Green Growth: Evidence from National Digital Economy Innovation and Development Pilot Zone in China

The National Digital Economy Innovation and Development Pilot Zone (NDEIDPZ) policy, as a form of digital place-based policy, can strongly promote the high-quality development of the digital economy in China, generating broad-based benefits across economic, social, and environmen...

Ultrarobust, Rapidly Recoverable Superhydrophobic Coatings with Self-Similar Micro/Nanostructures and Reinforced Interface for Aluminum Alloy Protection

Abstract In the field of aluminum alloy protection, constructing durable superhydrophobic coatings through a simple strategy is always a great challenge. Here, we report a functional coating with high mechanical robustness and superhydrophobic recoverability, composed of 1H, 1H,...

Demographic “doomsday” misses the mark

A dire prediction published in Science in 1960 anticipated a population singularity in 2026—we are not even close