Research works

A new framework for non-stationary spatio-temporal data fusion of multi-fidelity models

We propose a new scalable framework for spatio-temporal data fusion with multi-fidelity Gaussian processes (MFGPs) that enables fully likelihood-based inference for both stationary and non-stationary fidelity integration. The framework is designed for environmental applications,...

Service evaluation project: a journey through dementia distress management

Purpose Care home (CH) residents with dementia may exhibit distressed behaviours due to unmet needs, with non-pharmacological interventions being the first line intervention. This study aims to evaluate the efficiency of the Distressed Behaviour Pathway (DBP), delivered to care h...

The Untested Organisation: A Case for Examining Organisational Capability Before Failure

Modern organisations test the products, systems, controls and people they depend on before relying on them. Failure, when it occurs, is investigated afterwards: inquiries and reviews reconstruct the governance, incentives, culture and decision-making that made it possible, and co...

Hepatocyte OTUD1 promotes hepatic stellate cell activation and liver fibrosis by stabilizing HSP90β

Crosstalk between parenchymal and nonparenchymal cells of the liver mediates the activation of hepatic stellate cells (HSCs). Activated HSCs transform into myofibroblasts and produce the extracellular matrix (ECM), and massive ECM accumulation can affect liver function and eventu...

Deterministic modelling of end-milled sidewall topography with tool runout, tooth-radius difference and stationary cutter deflection

End milling is widely used to manufacture ribs, pockets, frames, and other structural features in mechanical and aerospace components. The resulting sidewall topography can affect dimensional accuracy, functional performance, and fatigue behaviour, so its prediction is relevant d...

Does pre-operative neutrophil–lymphocyte ratio predict patient-reported pain and functional outcomes at 12 months after anterior cervical discectomy and fusion?

INTRODUCTION: Preoperative neutrophil-lymphocyte ratio (NLR) has been found in various fields to be a predictor of post-operative pain and functional outcomes. To date no studies have looked at NLR in relation to patient outcomes after anterior cervical discectomy and fusion (ACD...

Exploring the supply chain resilience of food banks: a dynamic capabilities perspective

Purpose While supply chain resilience (SCR) has been extensively studied in for-profit contexts, nonprofit supply chains (NPSCs) remain underexplored. Drawing on dynamic capabilities theory (DCT), this study aims to investigate how food banks enact and integrate resilience capabi...

A Case of Acute Myeloid Leukemia, Myelodysplasia-Related (AML-MR) with Immunophenotypic Features Suggestive of B/Myeloid Mixed-Phenotype Acute Leukemia (MPAL), Harboring Multiple KMT2A Gene Amplifications

The amplification of KMT2A, a gene involved in hematopoietic stem cell function, is extremely rare in acute leukemias, especially in mixed-phenotype acute leukemia. We present the case of a 62-year-old patient diagnosed with acute myeloid leukemia, myelodysplasia-related (AML-MR)...

Head–Body–Tail Segmentation of Poultry 3D Point Clouds Under Different Annotation Budgets: A Comparison of PCA-Based Rules and PointNet++-Based Methods

Head–body–tail segmentation of poultry 3D point clouds is an underexplored task in precision poultry phenotyping. This study constructs a segmentation-oriented evaluation setting to examine how supervision source and annotation budget affect the relative performance of a principa...

Optimizing Public Service to Enhance Community Satisfaction: A CIPP Model Policy Evaluation at the Regional Secretariat of Merauke Regency, Indonesia

This study evaluates public service policy under Regional Regulation of Merauke Regency Number 10 of 2018 on Public Services at the Regional Secretariat of Merauke Regency, examined through the context, input, process, and product (CIPP) dimensions, and formulates improvement str...

Adapting in-cell ELISA to investigate the localization of hepatitis C virus envelope glycoproteins

The development of hepatitis C virus (HCV) vaccines remains challenging due to extensive viral genetic diversity and the complex biology of the envelope glycoproteins E1 and E2, which are major targets of broadly neutralizing antibodies and are associated with spontaneous viral c...

SIMULTANEOUS ESTIMATION OF CLIDINIUM BROMIDE AND CHLORDIAZEPOXIDE IN COMBINED DOSAGE FORM BY RP-HPLC

AbstractAnalytical chemistry is moreover engrossed on enhancements in experimental design, chemo - metricsand the making of novel measurement tools to offer improved chemical information. Analyticalchemistry has applications in forensics, bio - analysis, environmental analysis an...

Experiencing Tourism in Cruise Destinations: How Place Attachment and Quality of Life Shape Resident Attitudes

Cruise tourism is one of the fastest-growing segments of the global tourism industry, generating significant economic benefits while also creating challenges related to overtourism, congestion, environmental pressure, and residents’ quality of life. Understanding residents’ attit...

A Reproducible Workflow for AIS-Based ETA Forecasting: Evaluating the Influence of Data Preprocessing and Machine Learning Model Selection

Accurate Estimated Time of Arrival (ETA) forecasting is essential for improving operational planning and decision-making in modern ports. While machine learning has significantly enhanced ETA prediction using Automatic Identification System data, the impact of data preprocessing...

Clinical Features, Management, and Long-Term Outcomes of Chikungunya in Adult Populations: A Scoping Review

Chikungunya poses a major clinical and public health challenge due to its wide range of manifestations and, consequently, frequent misdiagnoses. This pitfall may lead to compromised long-term outcomes when treatment is inadequate. This scoping review aims to summarize the clinica...

A quality improvement initiative to optimize diagnostic and antimicrobial stewardship of ventilator-associated tracheitis in the pediatric intensive care unit

OBJECTIVE: To reduce frequency of endotracheal aspirate culture (EAC) collection and decrease antibiotic days of therapy (DOT) for ventilator-associated tracheitis (VAT). DESIGN: Quality improvement intervention. SETTING: Tertiary-care pediatric intensive care unit (PICU). PATIEN...

Universalism and its Others: Transcultural psychiatry and Swedish exceptionalism after 1945

This article traces the historical development of transcultural psychiatry in Sweden from the post-Second World War period to the early 21st century. It argues that the field emerged at the intersection of welfare universalism, humanitarian internationalism, and clinical encounte...

Easily Accessible and Highly Active Heterogeneous Nickel Catalyst Supported by Covalent Organic Framework for In Situ Ethylene Polymerization

ABSTRACT The heterogenization of homogeneous transition‐metal catalysts is a well‐established strategy for enabling oriented synthesis and precise morphological control of high‐molecular‐weight polyolefins. To date, however, the development of covalent organic framework (COF)‐sup...

Qalb: Largest State-of-the-Art Urdu Large Language Model for 230M Speakers with Systematic Continued Pre-Training

Despite remarkable progress in large language models, Urdua language spoken by over 230 million people remains critically underrepresented in modern NLP systems. Existing multilingual models demonstrate poor performance on Urdu-specific tasks, struggling with the language’s compl...

Quantifying and Counteracting the Impact of Erroneous and/or Incomplete Information via High-Order Predictive Modeling: Methodology and Illustrative Applications to Nuclear Reactor Models

This work highlights the major benefits of applying the “Fourth-Order Best-Estimate Predicted Results with Reduced Uncertainties Predictive Modeling” (4th-BERRU-PM) methodology to quantify and remedy the impact of possibly faulty computational or experimental information. After d...