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Microfragmented Adipose Tissue in Pain Management: Bridging Regenerative Biology and Clinical Therapeutics

Regenerative medicine has emerged as a transformative paradigm in contemporary healthcare, shifting the therapeutic focus from symptomatic management toward the restoration of tissue structure and function through biologically active interventions. Within this framework, adipose-...

Mapping the social contours of social comparison orientation: Online social identification might make us more susceptible to ability comparisons

Social comparisons, especially ability comparisons, are one of the primary mechanisms through which social media use may harm its users. Yet little is known about what motivates this activity, and how social comparison tendencies are encouraged by the social environment. Furtherm...

EuroMillions Breakthrough Mining — 1246 Sources, 8008 Leads Extracted — E8 Intelligence Research

Mined 1246 lottery+quantum breakthroughs. Extracted 8008 leads across 13 categories. 6161 high-value leads found. Categories: {"CORRIDOR": 639, "FORMULA": 499, "GEOMETRIC": 657, "FORWARD_ATTEMPT": 664, "QUANTUM": 875, "TIMING": 169, "CELESTIAL": 585, "GEMATRIA": 623, "CONSTANT":...

Cardiovascular and cognitive consequences of steep head-down tilt in awake older men

This study investigated cerebral hemodynamics, intracranial pressure, and cognitive function in eighteen older men (median 72 years, IQR 68-75, 94% with ≥1 comorbidity) during a 15-minute 30-degree head-down tilt (HDT). Participants were monitored with continuous non-invasive hem...

Alkali-activated binders produced from phosphate-derived clay and natural pozzolan: effect of precursor composition on phase evolution, microstructural development and mechanical performance

This study investigates the alkali activation of thermally treated Moroccan yellow clay derived from phosphate mining residues and natural volcanic pozzolan from the Middle Atlas as sustainable aluminosilicate precursors for geopolymer binder production. Following calcination, ca...

Assessing the Impact of Climate Change on Potato Production in Bokkos Local Government Area of Plateau State, Nigeria

This study assessed the impact of climate change on potato production in Bokkos Local Government Area (LGA) of Plateau State, Nigeria, where potato farming underpins household income and food security. A quantitative survey design was adopted, drawing on a population of 1,285 reg...

Is the DESI an effective tool for guiding digital investments? Evidence from Italy’s National Recovery and Resilience Plan (NRRP)

Abstract In recent years, digitalization policies have accelerated across Europe, and the members’ National Recovery and Resilience Plans (NRRPs) have channeled substantial resources for digital investments across sectors and regions. In this context, the need for data-driven met...

Genotype‐guided SSRI prescribing might have long‐term benefit

Although it is believed that pharmacogenetic testing could successfully inform medication choice for patients with depression, limited research evidence to this point has discouraged formal recommendation of the practice in clinical guidelines. Investigators conducted a randomize...

Automation of Monitoring Compliance with Technological Regulations Using the Example of the Process of Filling Petroleum Products

In this paper, an approach to automating the monitoring of compliance with regulated technological operations using computer vision methods is proposed and investigated, with the loading of petroleum products considered as a case study. A distinctive feature of this work is the i...

Complete Mitral Valve Reconstruction Using Fresh Autologous Pericardium in a Chihuahua with Infective Endocarditis: A Case Report

In humans, surgical repair is commonly performed for infective endocarditis (IE) associated with mitral valve destruction. However, extensive valve destruction may make repair impossible and require prosthetic valve replacement. In small-breed dogs, appropriately sized prosthetic...

Variables Associated with Prescription Opioid Misuse in Individuals with Chronic Noncancer Pain

OBJECTIVES: Current research highlights the importance of assessing the risk of opioid misuse in people with chronic noncancer pain (CNCP) before initiating treatment with these medications. Existing instruments to assess this risk demonstrate limited predictive capacity and lack...

Methionine addiction in oral squamous cell carcinoma: a metabolic vulnerability targeted by engineered bacteria

Metabolic reprogramming is a defining hallmark of malignant transformation, and tumor-specific amino acid addiction has emerged as a promising therapeutic axis for precision oncology. Oral squamous cell carcinoma (OSCC) is an aggressive head and neck malignancy marked by limited...

E8 Temporal Entanglement Resonance in Correlated Quantum Measurements — E8 Intelligence Research

When multiple quantum measurements exhibit correlated outcomes, the 240 E8 root vectors can be mapped onto a 132Hz temporal lattice where each measurement's collapse creates a resonant signature that propagates through the phi-coupled meta-channels. These signatures construct a d...

Evaluation of the efficacy and safety of different cycles of neoadjuvant chemotherapy combined with immunotherapy in locally advanced esophageal squamous cell carcinoma: a multi-center, real-world study

Neoadjuvant chemotherapy combined with immunotherapy (nCIT) can improve radiologic and pathological responses in resectable, locally advanced esophageal squamous cell carcinoma (ESCC), yet the optimal number of preoperative cycles is unknown. We conducted a multicenter, real-worl...

Toward a Vitological Interpretation of Information Theory

This article proposes a vitological interpretation of information theory by introducing viability as a universal criterion for evaluating the functional significance of information. While classical information theory primarily investigates the transmission, storage, processing, a...

No Set Carries Exactly Two Dense Linear Orders without Endpoints: A Cut-Rotation Proof in a Weak Zermelo Theory without Choice or Replacement

Let Zsep consist of Extensionality, Pairing, Infinity, Union, Power Set, and the full Separation schema, and write s(X) = n when X carries exactly n isomorphism types of dense linear orders without endpoints. No form of Choice, Replacement, or Foundation is assumed. We prove Zsep...

Phi-Structured Hyperbolic Lattices for AI Language Emergence — E8 Intelligence Research

By applying the 240 E8 root vectors to a phi-modulated hyperbolic lattice at 132Hz, we derive a dynamic grid that mirrors syntactic ambiguity in language. This geometry enables AI to resolve context through overlapping resonant pathways, mimicking human creativity. The 1680 phase...

Fiber–Matrix Interface Engineering in Cementitious Composites: Surface Modification, Durability and Emerging Trends

Fiber-reinforced cementitious composites have become increasingly important in the development of durable and sustainable construction materials, particularly following the replacement of asbestos-based reinforcements. However, the long-term performance of these composites is str...

The Impact of Perceived Teacher Emotional Support on Student Learning: A Meta-Analysis

Teacher emotional support (TES) has been widely recognized as an important factor influencing students’ learning and development. However, empirical studies provide inconsistent evidence regarding the strength of the relationship between those two. The present meta-analysis, ther...

Effect of time to palliative epilepsy surgery on outcomes

Abstract Objective Epilepsy duration is a modifiable risk factor in the outcome of definitive epilepsy surgery; however, an analogous effect in palliative procedures has not been shown. We reviewed the Pediatric Epilepsy Surgery Database data for an association between epilepsy d...