Research works

Assessing diabetes risk factors using explainable AI and SMOTEENN: a nutrition-based analysis in South Korea

The coronavirus disease (COVID-19) pandemic has influenced diabetes risk and management at the population level, underscoring the need for interpretable and data-driven risk assessment approaches. We developed an explainable machine learning framework integrating the KNHANES and...

Exosomes improved oxidative stress and apoptosis in BPA-induced nephrotoxicity in kidney cells through modulation of Nrf2/Keap1 signaling pathway

Bisphenol A (BPA) is an environmental toxicant known to induce nephrotoxicity primarily through oxidative stress–mediated inflammation and apoptosis. Mesenchymal stem cell-derived exosomes have recently emerged as promising cell-free therapeutic agents with antioxidant and anti-a...

The Carlo Temporal Engine V2

The Carlo Temporal Engine: A Reconstruction of Time A systems-theory framework that reconstructs time not as a fundamental dimension, but as an emergent behaviour of recursive systems. Across seven "unfolding passes," the paper develops time as a stability artefact generated to p...

Uniqueness of the averaging measure in the three-matrix Sutter--Berta--Tomamichel trace inequality

Sutter, Berta, and Tomamichel asked whether the averaging density \(\beta_0\) in their three-matrix trace inequality could be replaced by another probability distribution independent of the matrices. We show that it cannot. In every fixed dimension \(d\geq2\), if a Borel probabil...

Global Acoustic Geometry of Michel Flow in Painlevé-Gullstrand Coordinates

The acoustic metric of spherical accretion onto a Schwarzschild black hole (the Michel flow) in standard coordinates is singular at the gravitational horizon, and inside the acoustic horizon, the coordinate time loses its evolutionary meaning, which hinders the analysis of the su...

Self-Representation and the Emergence of Distinguishable States

This paper develops a minimal conceptual framework for examining how distinguishable states may emerge from a primitive condition of complete non-distinction. We denote this primitive condition by 0, not as the ordinary integer zero or the empty set, but as a state in which no in...

CAA-X V2.1: Cognitive Physicalism

V2.1 is a significant revision of V2 (Cognitive Physicalism), incorporating theoretical refinements, expanded mathematical formalization, and critical responses to feedback received since the original release. It preserves the core thesis of V2 — the rigorous isomorphism between...

Topological Condensed-Matter and Solid-State Physics: A Three-Axiom Reconstruction of Many-Body Matter, Crystals, Collective Excitations, Correlations, Topological Phases, and Transport

We develop a conditionally closed theoretical architecture for condensed-matter and solid-state physics from three physical axioms: microscopic ontic definiteness and finite localization, the physical reality of the spacetime-vacuum substrate, and persistent causal source–respons...

Topological–Historical Wave Dynamics: A Complete Global-Realist Theory of Physical Waves, Memory, Spectra, Conservation Laws, Computation, and Experimental Tests

We establish a logically closed, mathematically formulated, computationally executable, and experimentally falsifiable theory of wave dynamics within the global-realist framework. The construction inherits exactly three physical axioms: microscopic ontic definiteness and finite l...

Word-Level Bulk Marking for GPU Verification of Goldbach's Conjecture beyond 4x10^18

The exhaustive verification of Goldbach's conjecture has stood at 4x10^18 since 2014, established by Oliveira e Silva, Herzog and Pardi using roughly 770 one-core CPU years on distributed clusters. Recent GPU frameworks have improved throughput substantially but have not extended...

A Statistical Thermodynamic Lattice Model for Cu–In Coupled Substitution in Sphalerite

Version 2.0. This version corrects the equilibration argument of Section 4.7. Replica-exchange sampling reaches a state 3.1 eV over the box below anything the version 1 annealing protocol attained, showing that the two-trajectory test reported there was not a sufficient test of e...

Algorithmic imaginaries: Definition and critical questions

Algorithmic systems play an increasingly central role across a variety of social domains. Over the last few years, various concepts have been developed in the interdisciplinary field of algorithm studies to understand how people make sense of these systems and interact with them...

SCIENTIFIC-RESEARCH STUDY ONEARTHQUAKE FORECASTING

This scientific paper provides an extensive review and alternative theoretical paradigm regarding the genesis of tectonic earthquakes, challenging the traditional elastic rebound theory. Utilizing long-term observation data from the historical Niigata Experiment (Japan, 1964), vo...

SPROUT: AI-based Seedling emergence PRedictiOn and trait extraction Using RGB Time-series

Article and Images used in the ML pipeline for the publication funded by TANGENC.

A Comparative Floquet–Lyapunov Study of Perturbation-Induced Halo Orbit Instability in the Earth–Moon System

Halo orbits around the Earth–Moon L1–L3 underpin near-term cislunar infrastructure, from the Artemis Lunar Gateway to lunar communication relays, yet their operational viability depends on how strongly non-idealized forces reshape their intrinsic instability. While the linear sta...

The Idea of the Female Club: The Case of An Account of the Fair Intellectual-Club (Edinburgh, 1719)

Associational culture in the eighteenth century has been the subject of sustained attention in modern scholarship of the period, but relatively little attention has been paid to female clubs and associations. Usually this is because of the lack of evidence that female-only societ...

Above Room Temperature Ferroelectricity in Epitaxially Strained KTaO 3

ABSTRACT Epitaxial strain is a powerful means to engineer emergent phenomena in thin films and heterostructures. Here, we demonstrate that , a cubic perovskite in bulk form, can be epitaxially strained into a highly tunable ferroelectric. films grown commensurate to (001) substra...

The Smithian Fold Theory V3 Theory of Everything

The Smithian Fold Theory V3 Theory of Everything, version 0.3.0, integrates the newly admitted Smithian Fold Theory Foundation result that the structural One is pure consciousness: complete undivided presentation before observer, observed, content, succession, report or substrate...

Perturbation Spectrum of Michel Flow: Acoustic, Vortical, and Entropy Modes

The spectrum of linear perturbations of relativistic spherical accretion onto a Schwarzschild black hole (Michel flow) is studied, carrying the Newtonian analysis of the spatial stability of Bondi accretion over to full general relativity. Small perturbations of a perfect fluid s...

Controlled Partial Reconstruction Width (CPR-WIDTH-V2.0)

Controlled Partial Reconstruction Width (CPR-Width) is a reconstruction-oriented structural parameter for finite combinatorial problems. Instead of measuring the complete candidate space, CPR-Width measures the maximum number of task-relevant components that must remain simultane...