Research works

A values-illustration definition of art, scored against a verbatim-grounded corpus

This is a short record, not a full paper. It states a definition of art, gives its provenance, and reports how well it fits a corpus of cases taken verbatim from the literature. The definition. “An object, action or product created or chosen deliberately to illustrate values.” Tw...

HYDROXYUREA-INDUCED PERSISTENT LEG ULCERATION: A CASE REPORT

Hydroxyurea is a first-line cytoreductive agent for high-risk essential thrombocythemia (ET) due to its efficacy in reducing thrombotic events. Although generally well tolerated, long-term use may lead to rare cutaneous complications, notably non-healing leg ulcers. We report the...

A liquid chromatography-tandem mass spectrometry-based candidate reference measurement procedure for the quantification of vancomycin in human serum and plasma

OBJECTIVES: Vancomycin is a glycopeptide antibiotic used to treat severe Gram-positive infections; its narrow therapeutic window makes therapeutic drug monitoring (TDM) critical. We report the development of a liquid chromatography-tandem mass spectrometry (LC-MS/MS) candidate re...

Masterbatch-enabled acceleration of polyolefin biodegradation under open air terrestrial environmental conditions

Abstract Polyolefins, commonly used in packaging and single-use products, are notoriously persistent in the environment, contributing significantly to environmental pollution. In scientific literature to date, polyolefins have not been reported to fully biodegrade. This study exa...

Run-Level Fault Detection and SHAP-Based Diagnosis of Persistent Classification Difficulty in the Tennessee Eastman Process

Reliable fault detection in nonlinear process systems requires both accurate classification and interpretable analysis of faults with weak or near-normal signatures. This study develops an explainable, data-driven, and temporally informed multiclass framework for the Tennessee Ea...

A missing continental impact melt sheet signal in the early Earth detrital zircon record

Abstract Impact-derived melting has been proposed as a significant process in the formation of Earth’s early crust which could mean that impact melts are a source for Earth’s oldest minerals including ancient zircons. However, the source lithology of many Archean and Hadean zirco...

The impact of hospital environment on patient behavior: the case of Ankara Bilkent city hospital

PURPOSE: This study aims to investigate how hospital environmental stimuli influence inpatients' pleasure, trust in physicians and behavioral intentions (revisit and recommendation) in a large public-private partnership (PPP) city hospital in Türkiye. Drawing on the stimulus-orga...

The heritage dilemma: balancing commercial viability with cultural integrity

Purpose This study aims to address a critical challenge in safeguarding intangible cultural heritage by examining how meaningful experiences stimulate word-of-mouth (WOM) storytelling in the context of Cantonese Opera. Moving beyond traditional outcome measures such as satisfacti...

A systematic review of clinical patterns and outcomes of acute organophosphate poisoning in Nigeria

Organophosphate (OP) poisoning is a major public health concern in Nigeria, driven by the widespread availability of pesticides such as Sniper (dichlorvos) and Otapiapia. Despite its high morbidity and mortality, local evidence remains fragmented across isolated case reports and...

Calibrating Mathematics Vocabulary Self-Efficacy: Domain-Specific Accuracy by Mathematics-Difficulty Risk Status

Knowledge of mathematics vocabulary is important for conceptual understanding, yet little is known about how students’ vocabulary self-efficacy corresponds to their performance or how accurately they judge their competence. This study examined relations between mathematics vocabu...

NanomedicineStrategies to Ameliorate Neuroinflammationand Prevent Secondary Neural Tissue Damage

Abstract The burden of neurological disease remains a global issue, continually rising, requiring the need for effective therapeutics to disrupt disease progression. Across neurological diseases, neuroinflammation presents as a shared pathophysiological hallmark, presenting a com...

Mechanisms underpinning the progression of nondysplastic Barrett's oesophagus to cancer

Barrett's oesophagus is the metaplastic precursor to oesophageal adenocarcinoma; it is initiated by exposure of the squamous oesophageal epithelium to acid reflux. Wound repair mechanisms lead to the migration of columnar cells into the denuded lower oesophageal niche. These colu...

Multimodal BERT exploration of uncertain project resilience evolution via textual and log data joint modeling

To address the need for dynamic project resilience evaluation under uncertainty and the difficulty of jointly modeling risk texts and execution logs, this study proposes a Multimodal-BERT joint modeling framework for analyzing project resilience evolution. The framework combines...

Guest-DrivenFlexibility in a Hydrogen-Bonded OrganicFramework for NH3 Capture

Abstract Ammonia (NH3) capture and low-energy release remain a critical challenge in adsorptive separation. Herein, we report a guest-driven flexible hydrogen-bonded organic framework (HOF), designated FDU-HOF-7, constructed from 1,3,5-benzenetricarboxylic acid. The as-synthesize...

Wheat Flour Substitution with Sacha Inchi Tea Leaf Powder: Effects on Physicochemical Properties, Starch Digestibility, and Sensory Attributes of Cookies

Sacha inchi (Plukenetia volubilis L.) leaves are an underutilized by-product of an expanding oilseed crop, yet their use as a food ingredient remains limited. This study evaluated sacha inchi tea leaf powder (STLP) as a partial replacement for wheat flour in cookies at 0%, 2.5%,...

TargetingArginine Metabolism via ArcR: BlestriareneB Suppresses Staphylococcus aureus BiofilmFormation and Cellular ATP Production

Abstract Blestriarene B (BB), a biphenanthrene compound isolated from the medicinal plant Bletilla striata, possesses antibacterial properties against Staphylococcus aureus; however, its molecular target and underlying mechanisms remain unclear. Arginine metabolism plays a pivota...

Multifactorial ecological framework for intestinal-type gastric cancer

Gastric cancer (GC) remains one of the leading causes of cancer-related mortality worldwide, with projections indicating increasing incidence and marked geographic variability across populations. Although multiple hypotheses have been proposed to explain this heterogeneity, inclu...

A Dynamic Epistemic Logic with Lying and Theory of Mind Limitations

Abstract Theory of mind (ToM) is the ability to attribute and reason about unobservable mental states of others, such as knowledge, beliefs, and intentions. ToM is needed in social interactions, negotiations, cooperation, and deception, but there is a limit to the recursive depth...

Early Clinical Safety and Performance of a Novel Paclitaxel-Coated Balloon Catheter in Superficial Femoral and Popliteal Arteries

Abstract This study aimed to assess the clinical safety and performance of the novel paclitaxel-coated balloon (PCB) catheter in the superficial femoral artery (SFA) and/or the popliteal artery (PA) in patients with de novo or non-stented restenotic lesions during routine clinica...

Step-brothers in arms, SAGA and ATAC co-activator complexes, use different strategies

Abstract Transcriptional co-activator complexes play essential roles in regulating gene transcription by integrating signals from transcription factors and chromatin. Among these, the SAGA (Spt-Ada-Gcn5 acetyltransferase) and ATAC (Ada Two-A Containing) complexes represent relate...