Research works

Construction of personal health knowledge graphs for clinical data harmonization in breast cancer

Integrating heterogeneous personal health data and maintaining clinical registries for breast cancer management is labor-intensive. This study presents an AI-powered virtual assistant transforming identifiable breast cancer patient data into interoperable personal health knowledg...

Thermoelasticity of mixed-mode cracks in layered transversely isotropic half-spaces

A three-dimensional spectral formulation is developed for steady thermoelastic penny-shaped cracks embedded in layered transversely isotropic half-spaces, with arbitrary stacking sequences and mechanically compliant and thermally resistive interfaces. Its central feature is a com...

Development and validation of the premixing-phase model in the three-dimensional fuel–coolant interaction code SEINA-3D

Premixing during a fuel–coolant interaction determines the three-dimensional melt–water–vapor state available to a subsequent steam explosion. This study develops and validates the premixing-phase model of the three-dimensional fuel–coolant interaction code SEINA-3D. The model ad...

Impulsivity, cognitive inflexibility, and brain network dysregulation in etomidate use disorder: A clinical and EEG microstate study

Etomidate, a short-acting GABA_A receptor modulator and emerging novel psychoactive substance, is increasingly abused non-medically. Despite rising clinical concern, the neuropsychological profiles of etomidate use disorder (EUD) remain poorly characterized, prompting this system...

Experimental study on operating characteristics of titanium-water heat pipe in wide temperature range below 200 C

Heat pipes, with their excellent heat transfer performance and absence of moving parts, are widely applied in the aerospace field for thermal management. The waste heat dissipation system of space high-temperature power operates within the temperature range of 100∼300 °C, which c...

Paired parental and product-of-conception genetic analysis for clinical management of recurrent pregnancy loss associated with chromosomal rearrangements

The etiology of recurrent pregnancy loss (RPL) is complex, with embryonic chromosomal abnormalities being a significant genetic factor. However, genetic testing of miscarriage tissues alone may fail to identify parental carriers, leading to inaccurate recurrence risk assessment....

Retinoid biology from embryonic patterning to adult tissue homeostasis: metabolism, RAR signaling, disease mechanisms, and clinical translation

Vitamin A gives rise to functionally distinct retinoids that regulate vision, embryonic patterning, and adult tissue homeostasis. The principal endogenous transcriptional ligand, all-trans-retinoic acid (ATRA), activates RARα, RARβ, and RARγ within RAR-RXR heterodimers; this mech...

High tacrolimus intrapatient variability is associated with graft loss after kidney transplantation: a systematic review and meta-analysis

Tacrolimus intrapatient variability (IPV) has been proposed as a predictor of adverse outcomes after kidney transplantation, but the magnitude and consistency of this association across IPV measurement methods remain unclear. We conducted a systematic review and meta-analysis of...

Self-reported pain, depressive symptoms and risk for cardiovascular diseases

Previous studies have found that both pain and depressive symptoms are deleteriously associated with cardiovascular diseases (CVD). The aim of current study was to investigate the joint association of pain and depressive symptoms with CVD risk. A total of 13,184 participants aged...

B2B influencer marketing collaborations: A relational governance perspective

Influencer marketing has grown rapidly in business markets, yet existing research remains largely rooted in consumer contexts and organization-centric perspectives. Little is known about how B2B influencers perceive collaborations with companies. Addressing this gap, this study c...

Lending in Need: Natural Disaster Shocks and Online Borrowing in Indonesia

Natural disasters can generate urgent household liquidity needs, yet little is known about how borrowing through digital lending platforms responds to disaster exposure. Using approved-loan records from a major FinTech platform in Indonesia, this study examines the relationship b...

Accurately Probing [Fe(CN)6] Defects in Prussian Blue Analogues

Abstract Prussian blue analogues AxM[Fe(CN)6]1–y·zH2O (A = Na, K, M = Fe, Mn) possess a rich crystal chemistry that allows their use as insertion materials for batteries, water treatment, and smart windows, among others, applications. Despite being simple in appearance, their syn...

Toward a Student-Centered Classification of Inquiry-Based Learning: Evidence of Validity and Differential Effects on Chinese Writing Outcomes

In mainland China, a teacher-centered tradition has produced a rigid curriculum that marginalizes student-centeredness. Despite its pedagogical potential, inquiry-based learning (IBL) remains largely confined to limited implementations and theoretical discourse, while existing cl...

TriAlign UDA for hybrid domain adaptation of frozen histopathology foundation model representations

Code release corresponding to the Scientific Reports manuscript TriAlign UDA for hybrid domain adaptation of frozen histopathology foundation model representations

Connectivity‐Dependent Mechanics of Main‐Chain Oligomers in Side‐Chain Liquid‐Crystalline Polyacrylate Networks

ABSTRACT Liquid‐crystalline elastomers (LCEs) combine orientational order with polymer‐network elasticity, yet the influence of molecular connectivity on their mechanics across different timescales remains poorly understood. Side‐chain polyacrylate LCEs containing main‐chain liqu...

Non‐Markovian Entanglement via Parametrically Mediated Molecular Cavity Optomechanics

ABSTRACT Quantum entanglement in molecular cavity optomechanical (COM) systems serves as a fundamental resource to explore quantum‐enhanced sensing, coherent molecular dynamics, and quantum information processing, which has been studied under Markovian approximation but not yet e...

Organizational Zemblanity: How Organizational Learning Can Reinforce Rigidity, Error, and Misalignment

Organizational learning can help organizations improve and adapt, but it can also reinforce error and misalignment. These negative outcomes are often interpreted as implementation problems or as signs of incomplete learning. We instead examine the possibility that dysfunction can...

A literature-weighted composite index for integrating reproductive dysfunction and cancer-associated molecular features: a reproducible computational pipeline

Abstract Objective: To construct a literature-weighted composite Disease Activity Index (DAI) integrating gene-expression and DNA-methylation features associated with reproductive dysfunction and cancer, and to establish a reproducible computational pipeline for calculating the i...

An evaluated gait-driven finite element framework for transfemoral limb–socket interface biomechanics and socket design evaluation

Abstract Background Residual limb–socket interface mechanics are central to transfemoral prosthetic comfort and stability, but their dependence on socket material, regional pressure loading, interfacial slip ( δ slip ), and interfacial friction ( µ ) remains insufficiently quanti...

Barriers Faced by EFL Students for Accessing Cyber Learning in Rural School

This study aims to identify the obstacles faced by EFL students in accessing cyber-based learning in rural schools. Using a qualitative approach, data were collected through interviews with twelve students in grades VII to IX. The findings reveal several interconnected challenges...