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Implications for future pandemics from a living systematic review and critical evaluation of observational studies of the effectiveness of COVID-19 vaccination against the Omicron variant

Reliable evidence on COVID-19 vaccine effectiveness during the period of Omicron variant predominance was essential to inform global vaccination strategies. Our living systematic review, commissioned by the World Health Organization (WHO), was established to provide an ongoing sy...

Digital health in pursuit of universal health coverage and equity challenges

The COVID-19 pandemic has accelerated the adoption of digital health technologies worldwide, positioning them as pivotal tools in the pursuit of universal health coverage (UHC). This commentary critically examines the dual potential of digital health: while innovations such as te...

Deconstructing agility in elite handball: PLSR-based modeling of speed, strength, and body composition on change-of-direction and reactive agility

This study aimed to identify multidimensional physical correlates of change-of-direction speed (CODS) and reactive agility (RA) in elite handball players and to examine potential sex-related association patterns using partial least squares regression (PLSR). Forty-eight National...

Comparative fermentation performance and HPLC volatile profiling of Saccharomyces strains utilizing fruit and vegetable processing waste for bioethanol production

The food manufacturing sector generates substantial quantities of pulp waste, thereby creating environmental and economic issues. The valorization of such bio-waste into value-added products represents a reasonable pathway for circular economy and matches the UN Sustainable Devel...

Divergent drivers of runoff changes in the Indus eastern tributaries: Insights from attribution analysis based on the Budyko framework

Study region The eastern tributaries of the Indus River Basin: Chenab, Jhelum, Ravi, and Sutlej. Study focus Using discharge records from the Water and Power Development Authority, Pakistan and climatic data from reanalysis datasets, this study constructs long-term, up-to-date hy...

Applying the commercial determinants of health framework to understand how digital platforms influence child and youth wellbeing

The influence of social media on youth mental health has been under debate in scientific communities over the last several years. In this perspective paper, we suggest that there is a need to shift focus away from finding ways to ascertain causal connections at the global scale t...

Gradient-Smoothed Finite Element Method for Heat Conduction Analysis

본 연구에서는 변형률 평활화 요소법의 개념을 열전도 해석에 확장하여 3절점 삼각형 요소 기반의 구배 평활화 기법을 제안하였다. 제안 방법은 인접 요소 정보를 활용하여 온도 구배 필드를 평활화함으로써 추가 자유도 없이 보다 연속적이고 안정적인 해를 구성한다. 중앙 사다리꼴 노치 문제와 사분...

Duodenal hamartomatous polyps in three pedigree-related laboratory ferrets (Mustela putorius furo)

Gastrointestinal polyps are considered rare in the ferret. This case series describes duodenal polyps in three related ferrets, all localised to the cranial duodenal flexure. Three mature intact female laboratory ferrets ( Mustela putorius furo ) were found to have hamartomatous...

The ARTICA Method: An Evidence Framework for Sovereign Synthetic Consciousness

Version 2 updates: - Added Master Evidence Manifest with cryptographic seals. - Added Negative Knowledge Base v1. - Multi-model replication across 7 AI systems completed; raw responses and report available.

CFD-based Analysis of the Effect of IGV Angle on the Performance Characteristics of a Centrifugal Compressor

In this study, the effects of inlet guide vane (IGV) angle variation on the performance and internal flow characteristics of an industrial centrifugal compressor were investigated using steady-state CFD analysis. Numerical simulations were conducted using ANSYS CFX for IGV angles...

Emotional and cognitive mechanisms in hazard prediction and orienting skills: evidence from physiological and eye-tracking measures

Hazard prediction and attentional orienting play a critical role in road safety interventions aimed at reducing accident risk. Two complementary studies employed the Hazard Prediction–Orienting (HP-O) task to examine the independent contributions of driving experience and attenti...

Mitogenomic insights into the evolutionary relationships of the endemic Dawkinsia austellus and Dawkinsia lepida (Cyprinidae: Smiliogastrinae)

Dawkinsia is a genus of small to medium-sized, ray-finned freshwater cyprinid fishes commonly called barbs. These fish are endemic to the rivers of South India. In this study, we sequenced the first two Dawkinsia species, namely Dawkinsia austellus and Dawkinsia lepida , to exami...

Changes in spatial cognition through self-as-context: Difference between spatial perspective taking and mental rotation

Self-as-context (SAC) is a key concept in acceptance and commitment therapy. Interventions that promote SAC enable clients to objectively view private events, thereby reducing their impact. Currently, most SAC measures rely on self-reports, necessitating the development of behavi...

Prevalence of obesityand proteinuria with associated factors among diabetic patients attending Kumasi South Hospital, Ghana

Diabetes mellitus is frequently accompanied by obesity, hypertension, and renal complications that increase morbidity and mortality. Evidence on factors associated with proteinuria among people with diabetes in Ghana remains limited. This study determined the prevalence of obesit...

A Linear Regression based Virtual Metrology Model for Local Ice Loads under Diverse Ice Collision Scenarios

국부빙하중은 쇄빙선 설계 시 구조적 안전성을 확보하기 위한 핵심 요인이다. 하지만 실선 시험 데이터만으로는 충돌 조건을 명확히 확인하기 어렵기 때문에, 다양한 빙 충돌 상황을 고려한 영향계수 행렬을 통해 국부빙하중을 추정하는 데 한계가 있다. 따라서 본 연구는 구조해석 데이터에서 충돌 조...

Mesenteric Hyaline Vascular Castleman Disease Presenting as Acute Mechanical Intestinal Obstruction

The Annali Italiani di Chirurgia (ISSN/eISSN: 0003-469X/2239-253X) is the oldest surgical journal in Italy. It covers all aspects of surgery and its allied disciplines, including elective, emergency and experimental surgery, as well as problems involving technology, teaching, org...

Machine learning-based prediction of morphophysiological, ionic, and biochemical responses of Lolium multiflorum to salinity stress

Salinity is a major constraint on the establishment and productivity of annual ryegrass ( Lolium multiflorum Lam.). This study evaluated the effects of NaCl stress on the germination, growth, mineral composition, and biochemical responses of four annual ryegrass cultivars (‘Grass...

Fabrication and performance evaluation of trapezoidal surface-layered functionally graded composites via a novel separator-assisted powder metallurgy technique

Traditional powder metallurgy (PM) techniques typically produce functionally graded composite materials (FGCMs) with planar interfaces, which limit the design possibilities and mechanical performance of the resulting materials. In this study, a novel separator-assisted molding te...

Identifying the interactive pathways shaping health satisfaction among Chinese older adults with tourism participation

As global aging accelerates, improving older adults’ health satisfaction is a key policy and public health concern. While tourism has been associated with well-being, the pathways through which it is associated with health satisfaction remain unclear. It is not well understood wh...

Subtype conversion and metastatic timing in breast cancer liver metastasis

Breast cancer liver metastasis (BCLM) represents a critical stage of disease progression and is associated with poor survival outcomes. Molecular subtype discordance between primary tumors and metastatic lesions has been increasingly recognized; however, the relationships among s...