Research works

A Potential Link Between Dyslipidemia and Inflammation in Patients with Schizophrenia: Insights from Sterols and HDL Profile Analysis

Dyslipidemia and inflammation are two hallmarks of schizophrenia (SCZ), but the link between these two conditions remains elusive. We studied 40 SCZ patients and 40 age- and sex-matched healthy controls (CTRL) analyzing serum total, low-density lipoprotein (LDL), and high-density...

Research on Differential Protection Strategy of Transformer Under Extreme Geomagnetically Induced Current

Geomagnetically induced current (GIC) flowing through power transformers causes core saturation, leading to local hot-spot overheating, abnormal vibration, increased noise, and even irreversible transformer damage and forced outage. To prevent catastrophic GIC-induced failures, r...

Biomolecular Pathways Linking Preoperative Chronic Stress to Postoperative Cardiovascular Dysfunction in Noncardiac Surgery

Postoperative cardiovascular complications remain a leading cause of morbidity and mortality after noncardiac surgery, yet current risk models do not incorporate psychosocial stress. With over 300 million noncardiac surgeries performed annually worldwide and a substantial burden...

Phase Transformation Directed Mn 2+ Incorporation and Chiral Self‐Assembly Unlocks Tunable Multicolor and Circularly Polarized Light Emission in Metal Halide Perovskite Nanoparticles

ABSTRACT This study leverages the phase transformation of zero‐dimensional (0D), non‐emissive, cesium lead bromide (Cs 4 PbBr 6 ) nanoparticles (NPs) to introduce controlled manganese (Mn 2+ ), lead (Pb 2+ ), and halide ions (Br − ,Cl − ) to the perovskite matrix in a bid to engi...

Integrating Cosmological Concepts into School Physics: Teaching Dark Energy and the Cosmological Constant through Metaphysical Inquiry

Contemporary cosmology assigns roughly 68.5% of the universe's energy density to dark energy, most simply described by the cosmological constant, Λ — yet this concept is almost entirely absent from secondary-school physics curricula. This paper proposes that carefully structured...

A refined adaptive logistic-trigonometric shear deformation theory for the precise bending analysis of functionally graded plates

This study presents a refined Logistic-Trigonometric Shear Deformation Theory (LTHT) for the bending and interlaminar stress analysis of functionally graded (FG) plates. The proposed theory utilizes a hybrid shape function that incorporates a logistic (sigmoid) component and a tr...

Experimental, finite element and machine learning based investigation of adhesive thickness on tensile strength of 3D printed PLA–CF composite lap joints

Additive manufacturing enables the fabrication of lightweight composite structures with improved mechanical performance and design flexibility. In fused deposition modelling, carbon fibre reinforced polylactic acid (PLA–CF) has attracted attention because of its higher stiffness...

Efficacy of Electroacupuncture Combined With Medication for Postherpetic Neuralgia

Objective To assess the clinical effectiveness of electroacupuncture combined with conventional medication for postherpetic neuralgia (PHN). Methods In this retrospective propensity score-matched study, the initial cohort comprised 146 patients with PHN admitted between January 2...

Acute kidney injury and renal replacement therapy: a critical synthesis of metabolic derangements and nutritional implications

Acute kidney injury (AKI) affects up to 50% of critically ill patients and is frequently complicated by severe metabolic derangements, requiring the initiation of replacement therapy (RRT) in 10–15% of cases. Despite substantial progress in the diagnosis of AKI and optimisation o...

The Wave State Model (WSM): Mathematical Formalization, Sparse Holographic Memory, and Minimum Action Inference in AI

The Wave State Model (WSM): Mathematical Formalization, Sparse Holographic Memory, and Minimum Action Inference in AI Working Paper - Independent Foundational Research Abstract The reliance on extractivist architectures, such as Large Language Models (LLMs) and discrete State Spa...

The Potential of Operando DRIFT Spectroscopy for Studying Degradation Mechanisms of Metal Oxide‐Based Electrochemical Cells

ABSTRACT High‐temperature electrochemical oxide devices are promising for many applications. These devices are known to be prone to degradation, yet the mechanisms remain poorly understood. In this perspective, we summarize the techniques most used to study degradation in metal o...

When to Remember: A Preregistered Study of Failure-Memory Delivery Timing in an LLM Coding Agent

Research on memory for LLM agents has concentrated on what to remember: what to store, how to consolidate it, and what to retrieve. This paper offers preregistered evidence that for failure memories, when and where the memory is delivered can matter more than what it says. On syn...

EuroMillions Breakthrough Mining — 1782 Sources, 13328 Leads Extracted — E8 Intelligence Research

Mined 1782 lottery+quantum breakthroughs. Extracted 13328 leads across 13 categories. 11327 high-value leads found. Categories: {"CORRIDOR": 1110, "FORMULA": 953, "GEOMETRIC": 725, "FORWARD_ATTEMPT": 1163, "QUANTUM": 1378, "TIMING": 208, "CELESTIAL": 1039, "GEMATRIA": 1108, "CONS...

Reduced Serum PON1 Lactonase Activity Is Associated with Mild Cognitive Impairment and Mixed Dementia

High-density lipoprotein (HDL)-associated paraoxonase-1 (PON1) contributes substantially to the antioxidant and anti-inflammatory functions of HDL. Impairment of these protective properties has been associated with Alzheimer’s disease (AD) and other forms of dementia, particularl...

ESG performance and business risk in Iberian companies: exploring gender diversity moderating effect

Purpose This study aims to examine the impact of Environmental, Social and Governance (ESG) performance on business risk and investigates how board gender diversity moderates this relationship. Design/methodology/approach Using panel data from 367 listed firms in Portugal and Spa...

Recent advances in the medical management of thyroid eye disease

Purpose of review Thyroid eye disease (TED) is a debilitating autoimmune disorder that can cause facial disfigurement, impair vision and reduce the quality of life. Novel insights into the pathogenesis of TED in the recent years have stimulated efforts to develop newer targeted m...

Outcome after cataract surgery with IOL implantation in adolescents and adults with juvenile idiopathic arthritis (JIA) associated or ANA-positive anterior uveitis

Purpose Cataract surgery in patients with chronic anterior uveitis may be associated with increased risk for complications and poor outcomes. This study analyses visual outcome, uveitis course and complications after cataract surgery with intraocular lens (IOL) implantation in ad...

Mood shifts and female representation: translating the locution of female demons in the Chinese canon The Journey to the West

The Journey to the West , a canonical work of Chinese mythology, has garnered centuries-long popularity both domestically and internationally. However, the portrayal of female demons in English translations of this novel remains significantly underexplored in academia, despite th...

Accelerating theDiscovery of Deep-Ultraviolet NonlinearOptical Materials by Combining Machine Learning Interatomic Potentialswith First-Principles Calculations: A Case of LiB2O3F

Abstract Discovering deep-ultraviolet (deep-UV) nonlinear optical (NLO) crystals is hampered by the vast structural search space and the cost of first-principles screening. Here, we establish an integrated framework coupling machine learning interatomic potential (MLIP) construct...

Novel Lipoprotein (a) Therapies: A Comprehensive Review

Abstract Purpose of Review Lipoprotein(a) [Lp(a)] is a genetically determined, independent risk factor for atherosclerotic cardiovascular disease and calcific aortic valve stenosis. Plasma Lp(a) levels are 70–90% heritable, largely unresponsive to lifestyle changes, and poorly co...