Research works

Epidural 0.125% ropivacaine is safe but insufficient for induced tibiotarsal joint pain

Abstract Background Epidural injection of a low concentration of the local anaesthetic ropivacaine produces analgesia without neurological deficits or ileus in people. Objective To determine if epidural 0.125% ropivacaine mitigates induced hindlimb lameness in horses while preser...

Autoantibodies neutralizing type I interferons underlie a third of cases of Chikungunya virus encephalitis or myelitis

Abstract Chikungunya virus (CHIKV) infection is typically not life-threatening but may, in rare cases, affect the central nervous system (CNS). In three cohorts of confirmed CHIKV cases from Martinique (French overseas territory) and Brazil (patients aged 0–89 years, n = 245), 20...

Modelling Tetralogy of Fallot: insights and limitations of animal models

Tetralogy of Fallot (TOF) is the commonest cyanotic congenital heart disease, arising from antero-cephalad deviation of the outlet septum during outflow tract (OFT) morphogenesis, producing a ventricular septal defect, overriding aorta, pulmonary stenosis, and right ventricular h...

Mechanical Properties of New Bamboo and Bamboo–Timber Hybrid Composites for Sustainable Construction: Experimental Investigation

This article presents an experimental investigation into the mechanical properties of new laminated bamboo and bamboo–timber hybrid composite materials for construction. A total of thirty-six bamboo and bamboo–timber hybrid composite specimens were manufactured, which include a n...

Imprecise Probabilistic Programming, Precisely: Credal Sets via Graded Monads, BDDs, and Semiring-Parametric Inference (Functional Pearl)

Imprecise probability generalizes standard probability theory by replacing a single distribution with a convex set of possible distributions. We show that this generalization requires no change to the standard BDD compilation and weighted model counting pipeline used by discrete...

A Generalized Shape Function Approach for Multimaterial Topology Optimization

ABSTRACT This paper presents a generalized shape function (gSF) approach for multi‐material topology optimization that utilizes a compact design space to produce optimized configurations featuring a large number of materials. Building upon 1D (linear), 2D (bilinear), and 3D (tril...

Conditions for Valid Offshore Methane Quantification

Methane emission estimates from offshore facilities are increasingly used for regulatory reporting and climate assessment, yet it remains unclear under what atmospheric conditions such estimates are physically meaningful. This study defines three necessary conditions for valid of...

Functional, Radiographic, and Patient-Reported Outcomes of Hybrid Fixation Versus Posterior Long Fusion for Double-Major Adolescent Idiopathic Scoliosis

Background: Posterior spinal fusion (PSF) provides reliable deformity correction for adolescent idiopathic scoliosis (AIS); however, it reduces lumbar mobility because of the fusion of motion segments. Hybrid fixation, which combines thoracic PSF with thoracolumbar/lumbar vertebr...

Large Schneiderian Membrane Perforation Repair During Sinus Lift Surgery: A Case Report

Background: Maxillary sinus floor elevation is a predictable procedure for implant rehabilitation in the posterior maxilla with reduced residual bone height. Schneiderian membrane perforation is the most frequent intraoperative complication during sinus lift surgery and may compr...

Cooperation, Defection, and Collapse: A Multiscale Game Theory Framework for Emphysema Progression

In the current paper, pulmonary emphysema is hypothesized to emerge from a nonlinear breakdown of cooperation across two tightly coupled systems: the extracellular matrix (ECM) crosslink network and the cellular populations responsible for its maintenance. To formalize this conce...

Spider–Geometry Engine: A Radial Tension, Phase-State & Observer-Coherence Subsystem for Carlo Collapse Theory v2 (With Visualiser)

Version 2 (PDF Included): Expanded framework complete with an interactive WebGL 3D geometric visualizer demonstrating the field equations running in real time. A fully structured Carlo Field Operator subsystem built from the intersection of mythic multi-limb symmetry, spider-web...

Flexural Response of Dense Polymeric BCC Lattice Beams: Experimental Benchmark and Limits of Homogenized Beam Descriptions

The flexural behaviour of body-centred cubic (BCC) lattice beams fabricated by stereolithography remains supported by limited experimental evidence, and available homogenized beam models are rarely confronted with data in the combined regime of high relative density, non-slender...

Delayed Feedback and Asymptotic Decay for a Time-Fractional Equation with the Spectral Fractional Laplacian

We study a delayed time-fractional semilinear evolution equation driven by the spectral fractional Laplacian. The model combines a Caputo time derivative, a source evaluated at the past state u(t−τ), and an absorption term evaluated at the present state u(t). The fractional struc...

AJOP-T: A High-Order Hardening Law for Continuous Teardrop Bounding Surface Plasticity

Soft-ground finite-element analyses commonly reduce curved Oedometer compression to one constant slope, obscuring where stress-level curvature affects boundary-value predictions. AJOP-T embeds the differentiable Arc Joint via Optimum Parameters map in continuous teardrop bounding...

Measuring Perceived Social Support After Disaster: Development and Validation of the Perceived Social Support in Disasters Scale (PSSDS-28)

Background/Objectives: Measuring perceived social support after disaster remains an unresolved psychometric problem: most instruments do not jointly capture the source of support (from whom it comes) and its function (how it operates), and none has been validated in a disaster-su...

Task-irrelevant stimuli robustly drive phasic pupil-linked arousal but only weakly affect memory formation

Abstract Brainstem arousal systems including the locus coeruleus noradrenaline system, respond transiently to behaviorally relevant events. This also drives dilations of the pupil, which are often observed during cognitive tasks. The strength of pupil responses during encoding of...

Flux, Banter, and ABBA Collapse v2 (With Visualiser)

Flux, Banter, and ABBA Collapse presents a formalisation of the Banternator Engine V‑Ω‑RAVE, a semantic‑flux reactor designed to translate human banter, emotional tone, and chaotic narrative energy into structured auxiliary fields within the Carlo ecosystem. This work establishes...

The Disco Collapse Engine (V‑Ω‑DISCO): A Collapse‑Reactive Auxiliary Carlo Engine v2 (With Visualiser)

Carlo Field Mechanics v2 — Interactive Geometric Visualizer This document details version 2 (v2) of the Carlo Field Mechanics Interactive Visualizer, a standalone WebGL/Three.js simulation environment designed to model dynamic quantum-like vector field dynamics and multi-manifold...

Excitonic Structure in CsPbBr3 Nanocubes,Nanorods, and Nanoplatelets: The Effect of Dimensionality

Abstract We present a theoretical study comparing the excitonic ground-state properties of CsPbBr3 nanocrystals with different dimensionality: nanorods (quasi-1D), nanoplatelets (quasi-2D), and nanocubes (quasi-3D). All three systems are described on an equal footing, by means of...

The Behavioral Architecture of Dietary Salt Reduction Among Hypertensive Population in Sabah, Malaysia: A Descriptive Qualitative Inquiry

Dietary patterns, not medical adherence, make it dif8icult to reduce salt in the population. This is due to the complex structure of the house. Hypertensive residents living in communities in Sabah, Malaysia, have dif8iculty adhering to a low-salt diet due to factors such as fami...