Research works

Robotic pancreatoduodenectomy in the high-difficulty tier: a retrospective cohort stratified by PD-ROBOSCORE

As a retrospective feasibility and safety analysis, this study explores the application of robotic pancreatoduodenectomy(RPD) in patients with different PD-ROBOSCORE grades at our center, with a key focus on the safety of RPD for high-difficulty procedures. This study retrospecti...

Serum miR-378d is associated with liver stiffness and fibrosis risk in patients with metabolic dysfunction-associated steatotic liver disease

Tissue biopsy is the gold standard for diagnosing metabolic dysfunction-associated steatohepatitis (MASH), but it is invasive and time-consuming to analyze. This paper aimed to explore the association between serum miR-378d and liver stiffness and fibrosis risk in patients with m...

Effects of Daily Expense Tracking on Impulse Purchasing Tendencies Among College Students

Impulse purchasing among college students is increasingly relevant in consumer environments characterized by digital payments, promotional exposure, and reduced transactional friction. This study examined short-term change in impulse purchasing tendencies during a five-day daily...

Acetylated KLF5 as a therapeutic target mediating the anti-metastatic effects of doxycycline and methacycline in prostate cancer bone metastasis

Bone metastasis is a common and lethal complication of breast, prostate, and lung cancers. TGF-β in the bone microenvironment is pivotal for metastatic progression. We previously demonstrated that TGF-β induces acetylation of KLF5 at K369 and that acetylated KLF5 (Ac-KLF5) drives...

Molecular breeding for resistance against powdery mildew in tomato: an overview

Powdery mildew is a group of plant diseases caused by fungi of the Erysiphaceae family and threatening virtually all important crop plants. The main causative agents of powdery mildew in tomato are the fungi Leveilula taurica and Erysiphe neolycopersici . The genetic basis of tom...

Exploring the survivability of higher-order multiple protostellar systems – The case of VLA1623

Abstract Higher-order protostellar systems (≥3 components) are commonly observed in the early stages of low-mass star formation. A persistent question in star formation and evolution is whether these higher-order protostellar systems survive as gravitationally bound systems or di...

Context-dependent localization and expression of glutamate and GABA and their machinery in microglia

Microglia are central regulators of brain homeostasis and synaptic architecture, but whether they, like astrocytes, act as reservoirs and handlers of glutamate and GABA is unknown. Using post-embedding immunogold electron microscopy, we provide the first ultrastructural evidence...

Application of machine learning to identify predictors of bone health in older male populations in Taiwan

Approximately 1 in 8 men over the age of 50 will experience a fragility fracture. Unlike women, men exhibit a gradual decline in bone mineral density beginning in their 60s. While multiple linear regression (MLR) has been the standard approach in osteoporosis risk modeling, machi...

Thoracolumbar fascia injury and other independent predictors of long-term residual low back pain 3 months after percutaneous kyphoplasty for thoracolumbar osteoporotic vertebral compression fractures

To identify independent risk factors for persistent residual low back pain at 3 months after isolated percutaneous kyphoplasty (PKP), and provide standardized clinical evidence for preoperative high-risk patient screening, standardized intraoperative manipulation, and long-term p...

Implementing milestone-based assessment to document surgical competence progression in an obstetrics and gynecology residency program: a mixed-methods study from Latin America

Competency-based medical education emphasizes outcomes and developmental progression, yet traditional numeric evaluations often fail to capture changes in surgical competence over time. Surgical milestones offer a structured framework for formative assessment, but their adaptatio...

Aerodynamic performance of combined bogie fairings in an 8-car high-speed train

Aerodynamic drag accounts for 75%–80% of the total running resistance of high-speed trains operating above 300 km/h, and the bogie region significantly contributes to this drag due to its complex separated flow structures. This study investigates the aerodynamic performance and d...

The Impact of Short-Form Digital Content on Social Awareness Among Nursing Students in a Private College

Short-form digital content has become an increasingly prominent mode of communication and information sharing among college students, particularly through platforms such as TikTok, Instagram Reels, and YouTube Shorts. This study examined whether exposure to short-form digital con...

Google trends analysis of emerging tobacco and nicotine products in countries with the highest tobacco production and marketing between 2015 and 2024

Tobacco use remains one of the leading global public health threats. In recent years, emerging nicotine products—particularly electronic cigarettes and heated tobacco products—have attracted growing attention. Monitoring online search behaviour provides timely insights into publi...

From Virtual Aggression to School Aggression: A Conceptual Model of Online Gaming, Moral Disengagement, Emotional Dysregulation, and Adolescent Violence

The relationship between violent online gaming and adolescent school-based aggression has generated decades of inconsistent empirical findings, largely because existing research has treated virtual aggression exposure as a direct predictor of behavior rather than specifying the p...

Mitochondria-ER contact sites in neurodegeneration: a homeostatic hub linking metabolic stress, neuroinflammation, and therapeutic opportunities

Neurodegenerative diseases (NDDs) involve self-amplifying interactions among proteotoxic stress, mitochondrial dysfunction, and neuroinflammation. Emerging evidence increasingly implicates mitochondria-endoplasmic reticulum contact sites (MERCs) as dynamic homeostatic hubs that m...

External load profiles across game-based training formats, friendly matches, and official matches in elite professional soccer players

This study compared the per-minute external load profiles of different game-based training formats with those of friendly and official matches in elite professional soccer players. Eighteen elite male professional soccer players competing in the Turkish Super League (age: 26.3 ±...

Comparing 432 Hz And 440 Hz Music In Relation To Emotional Safety Among Hospitality Management Students

Music listening is frequently used to regulate emotions and manage stress, but limited evidence exists regarding whether music tuning frequency is associated with emotional safety among students. This exploratory study compared changes in emotional safety among Hospitality Manage...

Plasmonic-enhanced lanthanide nanotransducers for mid-infrared detection

Advanced mid-infrared (MIR) detection underpins a wide range of applications from chemical sensing to thermal imaging. Conventional MIR photodetectors rely on narrow-bandgap semiconductors that typically require cryogenic cooling, whereas uncooled alternatives suffer from inheren...

Experimental and CFD investigation of heat transfer in high-power avionics equipment

Reliable thermal verification of high-power-density avionics is challenging because densely packed circuit boards and narrow cooling passages complicate detailed modeling and experimental validation. This study evaluates the thermal performance of an avionics enclosure using an i...

Interventions to reduce diabetes-related distress among adults with type 1 and type 2 diabetes: protocol for a systematic review and meta-analysis

Diabetes distress (DD) refers to the emotional and psychological burden experienced by individuals living with diabetes. Randomized controlled trials (RCTs) have investigated the efficacy of interventions on DD among adults with type 1 diabetes or type 2 diabetes. We aimed to sys...